登録情報 | データベース: PDB / ID: 4l8r |
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タイトル | Structure of mrna stem-loop, human stem-loop binding protein and 3'hexo ternary complex |
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要素 | - 3'-5' exoribonuclease 1
- HISTONE MRNA STEM-LOOP
- Histone RNA hairpin-binding protein
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キーワード | RNA/RNA BINDING PROTEIN/HYDROLASE / RNA-RNA BINDING PROTEIN-HYDROLASE COMPLEX / HISTONE MRNA 3'-END PROCESSING / HISTONE MRNA TRANSLATION / MICRORNA HOMEOSTASIS / 5.8S RRNA 3 -END MATURATION / ZFP100 / LSM11 / NUCLEUS |
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機能・相同性 | 機能・相同性情報
histone mRNA stem-loop binding complex / histone pre-mRNA stem-loop binding / rRNA 3'-end processing / mRNA 3'-end processing by stem-loop binding and cleavage / cap-dependent translational initiation / exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / histone pre-mRNA DCP binding / histone pre-mRNA 3'end processing complex / SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs / Transport of the SLBP Dependant Mature mRNA ...histone mRNA stem-loop binding complex / histone pre-mRNA stem-loop binding / rRNA 3'-end processing / mRNA 3'-end processing by stem-loop binding and cleavage / cap-dependent translational initiation / exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) / histone pre-mRNA DCP binding / histone pre-mRNA 3'end processing complex / SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs / Transport of the SLBP Dependant Mature mRNA / regulatory ncRNA-mediated gene silencing / RNA Polymerase II Transcription Termination / maturation of 5.8S rRNA / mRNA transport / Major pathway of rRNA processing in the nucleolus and cytosol / 3'-5' exonuclease activity / ribosome binding / 3'-5'-RNA exonuclease activity / 加水分解酵素; エステル加水分解酵素 / rRNA binding / ribonucleoprotein complex / mRNA binding / nucleolus / RNA binding / nucleoplasm / identical protein binding / nucleus / metal ion binding / cytoplasm / cytosol類似検索 - 分子機能 Histone RNA hairpin-binding protein RNA-binding domain / Histone RNA stem-loop-binding protein SLBP1/SLBP2 / Histone RNA hairpin-binding protein, RNA-binding domain / SLBP, RNA-binding domain superfamily / Histone RNA hairpin-binding protein RNA-binding domain / : / : / SAP domain / Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 / SAP domain superfamily ...Histone RNA hairpin-binding protein RNA-binding domain / Histone RNA stem-loop-binding protein SLBP1/SLBP2 / Histone RNA hairpin-binding protein, RNA-binding domain / SLBP, RNA-binding domain superfamily / Histone RNA hairpin-binding protein RNA-binding domain / : / : / SAP domain / Transcription Termination Factor Rho, Rna-binding Domain; Chain A, Domain 1 / SAP domain superfamily / Exonuclease / Exonuclease, RNase T/DNA polymerase III / EXOIII / SAP domain / SAP motif profile. / Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation / SAP domain / Helicase, Ruva Protein; domain 3 / Ribonuclease H-like superfamily/Ribonuclease H / Nucleotidyltransferase; domain 5 / Ribonuclease H superfamily / Ribonuclease H-like superfamily / 2-Layer Sandwich / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 RNA / RNA (> 10) / Histone RNA hairpin-binding protein / 3'-5' exoribonuclease 1類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.6 Å |
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データ登録者 | Tan, D. / Tong, L. |
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引用 | ジャーナル: Science / 年: 2013 タイトル: Structure of Histone Mrna Stem-Loop, Human Stem-Loop Binding Protein, and 3'Hexo Ternary Complex. 著者: Tan, D. / Marzluff, W.F. / Dominski, Z. / Tong, L. |
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履歴 | 登録 | 2013年6月17日 | 登録サイト: RCSB / 処理サイト: RCSB |
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置き換え | 2013年7月10日 | ID: 4HXH |
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改定 1.0 | 2013年7月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年11月15日 | Group: Refinement description / カテゴリ: software |
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