登録情報 | データベース: PDB / ID: 4iqp |
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タイトル | Crystal Structure of HCRA-W1266A |
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要素 | Botulinum neurotoxin type A |
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キーワード | TOXIN / Botulinum Neurotoxin / receptor binding domain / Ganglioside binding loop |
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機能・相同性 | 機能・相同性情報
host cell junction / negative regulation of neurotransmitter secretion / bontoxilysin / host cell presynaptic membrane / host cell cytoplasmic vesicle / host cell cytosol / protein transmembrane transporter activity / metalloendopeptidase activity / toxin activity / membrane => GO:0016020 ...host cell junction / negative regulation of neurotransmitter secretion / bontoxilysin / host cell presynaptic membrane / host cell cytoplasmic vesicle / host cell cytosol / protein transmembrane transporter activity / metalloendopeptidase activity / toxin activity / membrane => GO:0016020 / host cell plasma membrane / proteolysis / zinc ion binding / extracellular region / membrane類似検索 - 分子機能 Clostridium neurotoxin, translocation / Clostridium neurotoxin, Translocation domain / Clostridium neurotoxin, translocation domain / Clostridial neurotoxin zinc protease / Botulinum/Tetanus toxin, catalytic chain / Clostridium neurotoxin, receptor binding N-terminal / Clostridium neurotoxin, receptor-binding C-terminal / Clostridium neurotoxin, C-terminal receptor binding / Clostridium neurotoxin, N-terminal receptor binding / Kunitz inhibitor STI-like superfamily ...Clostridium neurotoxin, translocation / Clostridium neurotoxin, Translocation domain / Clostridium neurotoxin, translocation domain / Clostridial neurotoxin zinc protease / Botulinum/Tetanus toxin, catalytic chain / Clostridium neurotoxin, receptor binding N-terminal / Clostridium neurotoxin, receptor-binding C-terminal / Clostridium neurotoxin, C-terminal receptor binding / Clostridium neurotoxin, N-terminal receptor binding / Kunitz inhibitor STI-like superfamily / Trefoil (Acidic Fibroblast Growth Factor, subunit A) - #50 / Trefoil (Acidic Fibroblast Growth Factor, subunit A) / Trefoil / Jelly Rolls - #200 / Neutral zinc metallopeptidases, zinc-binding region signature. / Concanavalin A-like lectin/glucanase domain superfamily / Jelly Rolls / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 Botulinum neurotoxin type A / Botulinum neurotoxin type A類似検索 - 構成要素 |
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生物種 | ![](img/tx_bacteria.gif) Clostridium botulinum (ボツリヌス菌) |
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手法 | X線回折 / 分子置換 / 解像度: 2.3 Å |
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データ登録者 | Fu, Z. / Kroken, A.R. / Barbieri, J.T. / Kim, J.-J.P. |
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引用 | ジャーナル: Infect.Immun. / 年: 2013 タイトル: Enhancing the Protective Immune Response against Botulism. 著者: Przedpelski, A. / Tepp, W.H. / Kroken, A.R. / Fu, Z. / Kim, J.J. / Johnson, E.A. / Barbieri, J.T. |
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履歴 | 登録 | 2013年1月12日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2013年5月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2013年7月10日 | Group: Database references |
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改定 1.2 | 2023年9月20日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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