Entry | Database: PDB / ID: 4dhx |
---|
Title | ENY2:GANP complex |
---|
Components | - 80 kDa MCM3-associated protein
- Enhancer of yellow 2 transcription factor homolog
|
---|
Keywords | TRANSPORT PROTEIN/DNA binding Protein / mRNA export / TRANSPORT PROTEIN-DNA binding Protein complex |
---|
Function / homology | Function and homology information
: / DUBm complex / transcription export complex 2 / nuclear pore nuclear basket / nucleosome organization / histone H3 acetyltransferase activity / negative regulation of insulin secretion involved in cellular response to glucose stimulus / SAGA complex / poly(A)+ mRNA export from nucleus / somatic hypermutation of immunoglobulin genes ...: / DUBm complex / transcription export complex 2 / nuclear pore nuclear basket / nucleosome organization / histone H3 acetyltransferase activity / negative regulation of insulin secretion involved in cellular response to glucose stimulus / SAGA complex / poly(A)+ mRNA export from nucleus / somatic hypermutation of immunoglobulin genes / mRNA export from nucleus / histone acetyltransferase activity / histone acetyltransferase / Transferases; Acyltransferases; Transferring groups other than aminoacyl groups / nuclear receptor coactivator activity / transcription elongation by RNA polymerase II / chromosome / HATs acetylate histones / histone binding / nuclear membrane / transcription coactivator activity / nucleic acid binding / chromatin binding / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / mitochondrion / nucleoplasm / nucleus / cytoplasm / cytosolSimilarity search - Function Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #1340 / Germinal-centre associated nuclear protein, MCM3AP domain / Germinal-centre associated nuclear protein, nucleoporin homology domain / Germinal-centre associated nuclear protein, CID domain / MCM3AP, RNA recognition motif / Binding region of GANP to ENY2 / Nucleoporin homology of Germinal-centre associated nuclear protein / MCM3AP domain of GANP / SAC3/GANP/THP3, conserved domain / SAC3/GANP family ...Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #1340 / Germinal-centre associated nuclear protein, MCM3AP domain / Germinal-centre associated nuclear protein, nucleoporin homology domain / Germinal-centre associated nuclear protein, CID domain / MCM3AP, RNA recognition motif / Binding region of GANP to ENY2 / Nucleoporin homology of Germinal-centre associated nuclear protein / MCM3AP domain of GANP / SAC3/GANP/THP3, conserved domain / SAC3/GANP family / ENY2/SUS1 / Transcription factor, enhancer of yellow 2 / Transcription factor EnY2 superfamily / Transcription factor e(y)2 / Serum Albumin; Chain A, Domain 1 / Proteasome component (PCI) domain / PCI domain profile. / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Helix non-globular / RNA-binding domain superfamily / Special / Orthogonal Bundle / Mainly AlphaSimilarity search - Domain/homology |
---|
Biological species | Homo sapiens (human) |
---|
Method | X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution: 2.1 Å |
---|
Authors | Stewart, M. / Jani, D. |
---|
Citation | Journal: Nucleic Acids Res. / Year: 2012 Title: Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export. Authors: Jani, D. / Lutz, S. / Hurt, E. / Laskey, R.A. / Stewart, M. / Wickramasinghe, V.O. |
---|
History | Deposition | Jan 30, 2012 | Deposition site: RCSB / Processing site: RCSB |
---|
Revision 1.0 | Jun 13, 2012 | Provider: repository / Type: Initial release |
---|
Revision 1.1 | Feb 28, 2024 | Group: Data collection / Database references Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
---|
|
---|