Entry | Database: PDB / ID: 4cyj |
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Title | Chaetomium thermophilum Pan2:Pan3 complex |
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Components | - PAB-DEPENDENT POLY(A)-SPECIFIC RIBONUCLEASE SUBUNIT PAN3-LIKE PROTEIN
- PAN2
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Keywords | TRANSFERASE / DEADENYLATION |
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Function / homology | Function and homology information
PAN complex / poly(A)-specific ribonuclease / poly(A)-specific ribonuclease activity / nuclear-transcribed mRNA poly(A) tail shortening / poly(A) binding / P-body / mRNA processing / nucleic acid binding / protein kinase activity / ATP binding / metal ion bindingSimilarity search - Function Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #5160 / Helix Hairpins - #3700 / PAN2-PAN3 deadenylation complex subunit PAN3 / Pan3 pseudokinase domain / Pan3 Pseudokinase domain / PAN2, UCH domain / PAN2-PAN3 deadenylation complex catalytic subunit PAN2 / : / Ubiquitin carboxyl-terminal hydrolase / PAN2 N-terminal ...Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #5160 / Helix Hairpins - #3700 / PAN2-PAN3 deadenylation complex subunit PAN3 / Pan3 pseudokinase domain / Pan3 Pseudokinase domain / PAN2, UCH domain / PAN2-PAN3 deadenylation complex catalytic subunit PAN2 / : / Ubiquitin carboxyl-terminal hydrolase / PAN2 N-terminal / Exonuclease / Exonuclease, RNase T/DNA polymerase III / EXOIII / Zinc finger, CCCH-type / Zinc finger C3H1-type profile. / Ubiquitin specific protease domain / Ubiquitin specific protease (USP) domain profile. / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Papain-like cysteine peptidase superfamily / Helix Hairpins / Ribonuclease H superfamily / Ribonuclease H-like superfamily / WD40-repeat-containing domain superfamily / Transferase(Phosphotransferase) domain 1 / Transferase(Phosphotransferase); domain 1 / WD40/YVTN repeat-like-containing domain superfamily / Serine/Threonine protein kinases, catalytic domain / Protein kinase domain profile. / Protein kinase domain / Protein kinase-like domain superfamily / Up-down Bundle / Orthogonal Bundle / Mainly AlphaSimilarity search - Domain/homology ADENOSINE-5'-TRIPHOSPHATE / PAN2-PAN3 deadenylation complex subunit PAN3 / PAN2-PAN3 deadenylation complex catalytic subunit PAN2Similarity search - Component |
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Biological species | CHAETOMIUM THERMOPHILUM (fungus) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.59 Å |
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Authors | Wolf, J. / Valkov, E. / Allen, M.D. / Meineke, B. / Gordiyenko, Y. / McLaughlin, S.H. / Olsen, T.M. / Robinson, C.V. / Bycroft, M. / Stewart, M. / Passmore, L.A. |
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Citation | Journal: Embo J. / Year: 2014 Title: Structural Basis for Pan3 Binding to Pan2 and its Function in Mrna Recruitment and Deadenylation Authors: Wolf, J. / Valkov, E. / Allen, M.D. / Meineke, B. / Gordiyenko, Y. / Mclaughlin, S.H. / Olsen, T.M. / Robinson, C.V. / Bycroft, M. / Stewart, M. / Passmore, L.A. |
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History | Deposition | Apr 11, 2014 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Jun 11, 2014 | Provider: repository / Type: Initial release |
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Revision 1.1 | Jun 25, 2014 | Group: Atomic model / Database references / Other |
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Revision 1.2 | Jul 30, 2014 | Group: Database references |
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