登録情報 データベース : PDB / ID : 4apj 構造の表示 ダウンロードとリンクタイトル Human angiotensin-converting enzyme in complex with BPPb 要素ANGIOTENSIN-CONVERTING ENZYME BRADYKININ-POTENTIATING PEPTIDE B 詳細キーワード HYDROLASE/HORMONE / HYDROLASE-HORMONE COMPLEX / ZINC METALLOPROTEASE / METALLOPEPTIDASE機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
mononuclear cell proliferation / cell proliferation in bone marrow / bradykinin receptor binding / regulation of angiotensin metabolic process / exopeptidase activity / substance P catabolic process / peptidyl-dipeptidase A / metalloendopeptidase inhibitor activity / tripeptidyl-peptidase activity / regulation of renal output by angiotensin ... mononuclear cell proliferation / cell proliferation in bone marrow / bradykinin receptor binding / regulation of angiotensin metabolic process / exopeptidase activity / substance P catabolic process / peptidyl-dipeptidase A / metalloendopeptidase inhibitor activity / tripeptidyl-peptidase activity / regulation of renal output by angiotensin / negative regulation of calcium ion import / positive regulation of peptidyl-cysteine S-nitrosylation / response to laminar fluid shear stress / negative regulation of gap junction assembly / metallodipeptidase activity / positive regulation of systemic arterial blood pressure / cellular response to aldosterone / hormone catabolic process / bradykinin catabolic process / angiogenesis involved in coronary vascular morphogenesis / response to thyroid hormone / antigen processing and presentation of peptide antigen via MHC class I / negative regulation of glucose import / vasoconstriction / hormone metabolic process / neutrophil mediated immunity / regulation of smooth muscle cell migration / regulation of hematopoietic stem cell proliferation / mitogen-activated protein kinase binding / embryo development ending in birth or egg hatching / chloride ion binding / mitogen-activated protein kinase kinase binding / positive regulation of neurogenesis / arachidonic acid secretion / eating behavior / post-transcriptional regulation of gene expression / heterocyclic compound binding / lung alveolus development / heart contraction / peptide catabolic process / response to dexamethasone / regulation of heart rate by cardiac conduction / regulation of systemic arterial blood pressure by renin-angiotensin / regulation of vasoconstriction / hematopoietic stem cell differentiation / peptidyl-dipeptidase activity / blood vessel remodeling / amyloid-beta metabolic process / angiotensin maturation / animal organ regeneration / Metabolism of Angiotensinogen to Angiotensins / positive regulation of vasoconstriction / carboxypeptidase activity / sperm midpiece / blood vessel diameter maintenance / response to nutrient levels / basal plasma membrane / kidney development / angiotensin-activated signaling pathway / female pregnancy / cellular response to glucose stimulus / brush border membrane / regulation of synaptic plasticity / hormone activity / metalloendopeptidase activity / regulation of blood pressure / vasodilation / metallopeptidase activity / male gonad development / peptidase activity / actin binding / toxin activity / spermatogenesis / endopeptidase activity / response to lipopolysaccharide / lysosome / calmodulin binding / response to hypoxia / endosome / response to xenobiotic stimulus / positive regulation of apoptotic process / external side of plasma membrane / negative regulation of gene expression / proteolysis / extracellular space / zinc ion binding / extracellular exosome / extracellular region / plasma membrane 類似検索 - 分子機能 Natriuretic peptide, conserved site / Atrial natriuretic peptide / Natriuretic peptides signature. / Natriuretic peptide / Natriuretic peptide / Peptidase family M2 domain profile. / Peptidase M2, peptidyl-dipeptidase A / Angiotensin-converting enzyme / Neutral zinc metallopeptidases, zinc-binding region signature. 類似検索 - ドメイン・相同性 ACETATE ION / Bradykinin-potentiating and C-type natriuretic peptides / Angiotensin-converting enzyme 類似検索 - 構成要素生物種 HOMO SAPIENS (ヒト)GLOYDIUS BLOMHOFFI (ニホンマムシ)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.6 Å 詳細データ登録者 Masuyer, G. / Schwager, S.L.U. / Sturrock, E.D. / Isaac, R.E. / Acharya, K.R. 引用ジャーナル : Sci.Rep. / 年 : 2012タイトル : Molecular Recognition and Regulation of Human Angiotensin-I Converting Enzyme (Ace) Activity by Natural Inhibitory Peptides.著者 : Masuyer, G. / Schwager, S.L.U. / Sturrock, E.D. / Isaac, R.E. / Acharya, K.R. 履歴 登録 2012年4月3日 登録サイト : PDBE / 処理サイト : PDBE改定 1.0 2012年10月17日 Provider : repository / タイプ : Initial release改定 1.1 2012年10月24日 Group : Database references改定 2.0 2020年3月11日 Group : Data collection / Derived calculations ... Data collection / Derived calculations / Other / Polymer sequence カテゴリ : chem_comp / entity_poly ... chem_comp / entity_poly / pdbx_database_status / struct_conn Item : _chem_comp.type / _entity_poly.pdbx_seq_one_letter_code_can ... _chem_comp.type / _entity_poly.pdbx_seq_one_letter_code_can / _pdbx_database_status.status_code_sf / _struct_conn.pdbx_leaving_atom_flag 改定 3.0 2020年7月29日 Group : Advisory / Atomic model ... Advisory / Atomic model / Data collection / Derived calculations / Structure summary カテゴリ : atom_site / atom_site_anisotrop ... atom_site / atom_site_anisotrop / chem_comp / entity / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / pdbx_unobs_or_zero_occ_atoms / struct_asym / struct_conn / struct_site / struct_site_gen Item : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _atom_site_anisotrop.pdbx_label_asym_id / _chem_comp.name / _pdbx_struct_assembly_gen.asym_id_list / _pdbx_unobs_or_zero_occ_atoms.label_asym_id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id 解説 : Carbohydrate remediation / Provider : repository / タイプ : Remediation改定 3.1 2023年12月20日 Group : Data collection / Database references ... Data collection / Database references / Refinement description / Structure summary カテゴリ : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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