Entry Database : PDB / ID : 4ajt Structure visualization Downloads & linksTitle The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI) ComponentsPROTEIN Z-DEPENDENT PROTEASE INHIBITOR Details Keywords BLOOD CLOTTING / ZPIFunction / homology Function and homology informationFunction Domain/homology Component
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) / Post-translational protein phosphorylation / negative regulation of endopeptidase activity / serine-type endopeptidase inhibitor activity / blood coagulation / heparin binding / extracellular space Similarity search - Function Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily / Serpin superfamily, domain 1 / Serpin (serine protease inhibitor) ... Antithrombin; Chain I, domain 2 / Antithrombin, subunit I, domain 2 / Alpha-1-antitrypsin; domain 1 / Alpha-1-antitrypsin, domain 1 / Serpin superfamily, domain 2 / Serpin family / Serpin domain / Serpin superfamily / Serpin superfamily, domain 1 / Serpin (serine protease inhibitor) / SERine Proteinase INhibitors / Roll / 2-Layer Sandwich / Mainly Beta / Alpha Beta Similarity search - Domain/homologyBiological species MUS MUSCULUS (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.5 Å DetailsAuthors Yan, Y. / Zhou, A. CitationJournal : Blood / Year : 2012Title : Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.Authors : Huang, X. / Yan, Y. / Tu, Y. / Gatti, J. / Broze, G.J.J. / Zhou, A. / Olson, S.T. History Deposition Feb 19, 2012 Deposition site : PDBE / Processing site : PDBERevision 1.0 Dec 5, 2012 Provider : repository / Type : Initial releaseRevision 1.1 Dec 26, 2012 Group : Database referencesRevision 1.2 Apr 24, 2013 Group : Structure summaryRevision 1.3 Jun 12, 2019 Group : Data collection / Database references / OtherCategory : citation_author / pdbx_database_proc / pdbx_database_statusItem : _citation_author.name / _pdbx_database_status.recvd_author_approvalRevision 1.4 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf
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