Entry Database : PDB / ID : 4aea Structure visualization Downloads & linksTitle Dimeric alpha-cobratoxin X-ray structure: Localization of intermolecular disulfides and possible mode of binding to nicotinic acetylcholine receptors ComponentsLONG NEUROTOXIN 1 Details Keywords TOXIN / THREE-FINGER TOXIN / NICOTINIC ACETYLCHOLINE RECEPTORFunction / homology Function and homology informationFunction Domain/homology Component
acetylcholine receptor inhibitor activity / ion channel regulator activity / toxin activity / extracellular region Similarity search - Function Snake three-finger toxin / Snake toxins signature. / Snake toxin, conserved site / CD59 / CD59 / Snake toxin-like superfamily / Ribbon / Mainly Beta Similarity search - Domain/homologyBiological species NAJA KAOUTHIA (monocled cobra)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.94 Å DetailsAuthors Rucktooa, P. / Osipov, A.V. / Kasheverov, I.E. / Filkin, S.Y. / Starkov, V.G. / Andreeva, T.V. / Bertrand, D. / Utkin, Y.N. / Tsetlin, V.I. / Sixma, T.K. CitationJournal : J.Biol.Chem. / Year : 2012Title : Dimeric Alpha-Cobratoxin X-Ray Structure: Localization of Intermolecular Disulfides and Possible Mode of Binding to Nicotinic Acetylcholine Receptors.Authors : Osipov, A.V. / Rucktooa, P. / Kasheverov, I.E. / Filkin, S.Y. / Starkov, V.G. / Andreeva, T.V. / Sixma, T.K. / Bertrand, D. / Utkin, Y.N. / Tsetlin, V.I. History Deposition Jan 9, 2012 Deposition site : PDBE / Processing site : PDBERevision 1.0 Jan 25, 2012 Provider : repository / Type : Initial releaseRevision 1.1 Aug 15, 2012 Group : Database referencesRevision 1.2 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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