[English] 日本語
Yorodumi
- PDB-3znj: Crystal structure of unliganded ClcF from R.opacus 1CP in crystal... -

+
Open data


ID or keywords:

Loading...

-
Basic information

Entry
Database: PDB / ID: 3znj
TitleCrystal structure of unliganded ClcF from R.opacus 1CP in crystal form 1.
Components5-CHLOROMUCONOLACTONE DEHALOGENASE
KeywordsLYASE / FERREDOXIN FOLD / DEHALOGENATION / 3-CHLOROCATECHOL PATHWAY
Function / homology
Function and homology information


muconolactone Delta-isomerase / muconolactone delta-isomerase activity / beta-ketoadipate pathway
Similarity search - Function
Muconolactone delta-isomerase / Muconolactone isomerase domain / Muconolactone delta-isomerase / Dimeric alpha+beta barrel / Dimeric alpha-beta barrel / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta
Similarity search - Domain/homology
Muconolactone Delta-isomerase
Similarity search - Component
Biological speciesRHODOCOCCUS OPACUS (bacteria)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.1 Å
AuthorsRoth, C. / Groening, J.A.D. / Kaschabek, S.R. / Schloemann, M. / Straeter, N.
Citation
Journal: Mol.Microbiol. / Year: 2013
Title: Crystal Structure and Catalytic Mechanism of Chloromuconolactone Dehalogenase Clcf from Rhodococcus Opacus 1Cp.
Authors: Roth, C. / Janosch, A.D. / Kaschabek, S.R. / Schloemann, M. / Straeter, N.
#1: Journal: Acta Crystallogr.,Sect.F / Year: 2012
Title: Crystallization and Preliminary Characterization of Chloromuconolactone Dehalogenase from Rhodococcus Opacus 1Cp.
Authors: Roth, C. / Kaschabek, S.R. / Groning, J.A.D. / Handrek, T. / Schlomann, M. / Strater, N.
History
DepositionFeb 14, 2013Deposition site: PDBE / Processing site: PDBE
Revision 1.0Mar 6, 2013Provider: repository / Type: Initial release
Revision 1.1Mar 20, 2013Group: Atomic model / Other
Revision 1.2Apr 24, 2013Group: Database references
Revision 1.3Dec 20, 2023Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Refinement description
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
Remark 700 SHEET DETERMINATION METHOD: DSSP THE SHEETS PRESENTED AS "1A" IN EACH CHAIN ON SHEET RECORDS BELOW ... SHEET DETERMINATION METHOD: DSSP THE SHEETS PRESENTED AS "1A" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "2A" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "4A" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "6A" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "8A" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "CA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "EA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "GA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "IA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "KA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "MA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "OA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "RA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "TA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "VA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "XA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "AA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "CA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL. THE SHEETS PRESENTED AS "EA" IN EACH CHAIN ON SHEET RECORDS BELOW IS ACTUALLY AN 8-STRANDED BARREL THIS IS REPRESENTED BY A 9-STRANDED SHEET IN WHICH THE FIRST AND LAST STRANDS ARE IDENTICAL.

-
Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

Downloads & links

-
Assembly

Deposited unit
1: 5-CHLOROMUCONOLACTONE DEHALOGENASE
2: 5-CHLOROMUCONOLACTONE DEHALOGENASE
3: 5-CHLOROMUCONOLACTONE DEHALOGENASE
4: 5-CHLOROMUCONOLACTONE DEHALOGENASE
5: 5-CHLOROMUCONOLACTONE DEHALOGENASE
6: 5-CHLOROMUCONOLACTONE DEHALOGENASE
7: 5-CHLOROMUCONOLACTONE DEHALOGENASE
8: 5-CHLOROMUCONOLACTONE DEHALOGENASE
9: 5-CHLOROMUCONOLACTONE DEHALOGENASE
A: 5-CHLOROMUCONOLACTONE DEHALOGENASE
B: 5-CHLOROMUCONOLACTONE DEHALOGENASE
C: 5-CHLOROMUCONOLACTONE DEHALOGENASE
D: 5-CHLOROMUCONOLACTONE DEHALOGENASE
E: 5-CHLOROMUCONOLACTONE DEHALOGENASE
F: 5-CHLOROMUCONOLACTONE DEHALOGENASE
G: 5-CHLOROMUCONOLACTONE DEHALOGENASE
H: 5-CHLOROMUCONOLACTONE DEHALOGENASE
I: 5-CHLOROMUCONOLACTONE DEHALOGENASE
J: 5-CHLOROMUCONOLACTONE DEHALOGENASE
K: 5-CHLOROMUCONOLACTONE DEHALOGENASE
L: 5-CHLOROMUCONOLACTONE DEHALOGENASE
M: 5-CHLOROMUCONOLACTONE DEHALOGENASE
N: 5-CHLOROMUCONOLACTONE DEHALOGENASE
O: 5-CHLOROMUCONOLACTONE DEHALOGENASE
P: 5-CHLOROMUCONOLACTONE DEHALOGENASE
R: 5-CHLOROMUCONOLACTONE DEHALOGENASE
S: 5-CHLOROMUCONOLACTONE DEHALOGENASE
T: 5-CHLOROMUCONOLACTONE DEHALOGENASE
U: 5-CHLOROMUCONOLACTONE DEHALOGENASE
V: 5-CHLOROMUCONOLACTONE DEHALOGENASE
W: 5-CHLOROMUCONOLACTONE DEHALOGENASE
X: 5-CHLOROMUCONOLACTONE DEHALOGENASE
Y: 5-CHLOROMUCONOLACTONE DEHALOGENASE
Z: 5-CHLOROMUCONOLACTONE DEHALOGENASE
a: 5-CHLOROMUCONOLACTONE DEHALOGENASE
b: 5-CHLOROMUCONOLACTONE DEHALOGENASE
c: 5-CHLOROMUCONOLACTONE DEHALOGENASE
d: 5-CHLOROMUCONOLACTONE DEHALOGENASE
e: 5-CHLOROMUCONOLACTONE DEHALOGENASE
f: 5-CHLOROMUCONOLACTONE DEHALOGENASE
hetero molecules


Theoretical massNumber of molelcules
Total (without water)454,688158
Polymers448,42940
Non-polymers6,259118
Water49,6312755
1
1: 5-CHLOROMUCONOLACTONE DEHALOGENASE
2: 5-CHLOROMUCONOLACTONE DEHALOGENASE
3: 5-CHLOROMUCONOLACTONE DEHALOGENASE
4: 5-CHLOROMUCONOLACTONE DEHALOGENASE
5: 5-CHLOROMUCONOLACTONE DEHALOGENASE
V: 5-CHLOROMUCONOLACTONE DEHALOGENASE
W: 5-CHLOROMUCONOLACTONE DEHALOGENASE
X: 5-CHLOROMUCONOLACTONE DEHALOGENASE
Y: 5-CHLOROMUCONOLACTONE DEHALOGENASE
Z: 5-CHLOROMUCONOLACTONE DEHALOGENASE
hetero molecules


Theoretical massNumber of molelcules
Total (without water)113,64139
Polymers112,10710
Non-polymers1,53429
Water18010
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Buried area32060 Å2
ΔGint-124.5 kcal/mol
Surface area40130 Å2
MethodPISA
2
A: 5-CHLOROMUCONOLACTONE DEHALOGENASE
B: 5-CHLOROMUCONOLACTONE DEHALOGENASE
C: 5-CHLOROMUCONOLACTONE DEHALOGENASE
D: 5-CHLOROMUCONOLACTONE DEHALOGENASE
E: 5-CHLOROMUCONOLACTONE DEHALOGENASE
F: 5-CHLOROMUCONOLACTONE DEHALOGENASE
G: 5-CHLOROMUCONOLACTONE DEHALOGENASE
H: 5-CHLOROMUCONOLACTONE DEHALOGENASE
I: 5-CHLOROMUCONOLACTONE DEHALOGENASE
J: 5-CHLOROMUCONOLACTONE DEHALOGENASE
hetero molecules


Theoretical massNumber of molelcules
Total (without water)113,70340
Polymers112,10710
Non-polymers1,59630
Water18010
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Buried area32340 Å2
ΔGint-114.5 kcal/mol
Surface area40380 Å2
MethodPISA
3
6: 5-CHLOROMUCONOLACTONE DEHALOGENASE
7: 5-CHLOROMUCONOLACTONE DEHALOGENASE
8: 5-CHLOROMUCONOLACTONE DEHALOGENASE
9: 5-CHLOROMUCONOLACTONE DEHALOGENASE
a: 5-CHLOROMUCONOLACTONE DEHALOGENASE
b: 5-CHLOROMUCONOLACTONE DEHALOGENASE
c: 5-CHLOROMUCONOLACTONE DEHALOGENASE
d: 5-CHLOROMUCONOLACTONE DEHALOGENASE
e: 5-CHLOROMUCONOLACTONE DEHALOGENASE
f: 5-CHLOROMUCONOLACTONE DEHALOGENASE
hetero molecules


Theoretical massNumber of molelcules
Total (without water)113,70340
Polymers112,10710
Non-polymers1,59630
Water724
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Buried area31920 Å2
ΔGint-125.4 kcal/mol
Surface area40460 Å2
MethodPISA
4
K: 5-CHLOROMUCONOLACTONE DEHALOGENASE
L: 5-CHLOROMUCONOLACTONE DEHALOGENASE
M: 5-CHLOROMUCONOLACTONE DEHALOGENASE
N: 5-CHLOROMUCONOLACTONE DEHALOGENASE
O: 5-CHLOROMUCONOLACTONE DEHALOGENASE
P: 5-CHLOROMUCONOLACTONE DEHALOGENASE
R: 5-CHLOROMUCONOLACTONE DEHALOGENASE
S: 5-CHLOROMUCONOLACTONE DEHALOGENASE
T: 5-CHLOROMUCONOLACTONE DEHALOGENASE
U: 5-CHLOROMUCONOLACTONE DEHALOGENASE
hetero molecules


Theoretical massNumber of molelcules
Total (without water)113,64139
Polymers112,10710
Non-polymers1,53429
Water18010
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Buried area32080 Å2
ΔGint-118.5 kcal/mol
Surface area40610 Å2
MethodPISA
Unit cell
Length a, b, c (Å)151.140, 79.430, 198.970
Angle α, β, γ (deg.)90.00, 93.41, 90.00
Int Tables number4
Space group name H-MP1211
Noncrystallographic symmetry (NCS)NCS oper: (Code: given / Matrix: (1), (1), (1))

-
Components

#1: Protein ...
5-CHLOROMUCONOLACTONE DEHALOGENASE / CLCF


Mass: 11210.717 Da / Num. of mol.: 40
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) RHODOCOCCUS OPACUS (bacteria) / Strain: 1CP / Plasmid: PETROCLCF / Production host: ESCHERICHIA COLI (E. coli) / References: UniProt: Q8G9L0
#2: Chemical...
ChemComp-CL / CHLORIDE ION


Mass: 35.453 Da / Num. of mol.: 40 / Source method: obtained synthetically / Formula: Cl
#3: Chemical...
ChemComp-EDO / 1,2-ETHANEDIOL / ETHYLENE GLYCOL


Mass: 62.068 Da / Num. of mol.: 78 / Source method: obtained synthetically / Formula: C2H6O2
#4: Water ChemComp-HOH / water


Mass: 18.015 Da / Num. of mol.: 2755 / Source method: isolated from a natural source / Formula: H2O

-
Experimental details

-
Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

-
Sample preparation

CrystalDensity Matthews: 2.88 Å3/Da / Density % sol: 57.4 % / Description: NONE

-
Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: BESSY / Beamline: 14.2 / Wavelength: 0.91841
DetectorType: MARRESEARCH / Detector: CCD / Details: MIRRORS
RadiationMonochromator: DOUBLE CRYSTAL MONOCHROMATOR / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthWavelength: 0.91841 Å / Relative weight: 1
ReflectionResolution: 2.1→20 Å / Num. obs: 261677 / % possible obs: 95.3 % / Observed criterion σ(I): 3.3 / Redundancy: 3.3 % / Biso Wilson estimate: 25.74 Å2 / Rmerge(I) obs: 0.04 / Net I/σ(I): 18.2
Reflection shellResolution: 2.1→2.21 Å / Redundancy: 3.3 % / Rmerge(I) obs: 0.18 / Mean I/σ(I) obs: 6.7 / % possible all: 90

-
Processing

Software
NameVersionClassification
PHENIX(PHENIX.REFINE: DEV_1172)refinement
MOSFLMdata reduction
SCALAdata scaling
MOLREPphasing
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: PDB ENTRY 1MLI

1mli


Resolution: 2.1→19.898 Å / SU ML: 0.2 / σ(F): 0 / Phase error: 21.88 / Stereochemistry target values: ML
RfactorNum. reflection% reflection
Rfree0.2235 1340 0.5 %
Rwork0.1641 --
obs0.1644 261632 95.28 %
Solvent computationShrinkage radii: 0.8 Å / VDW probe radii: 1.1 Å / Solvent model: FLAT BULK SOLVENT MODEL
Refinement stepCycle: LAST / Resolution: 2.1→19.898 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms31551 0 352 2755 34658
Refine LS restraints
Refine-IDTypeDev idealNumber
X-RAY DIFFRACTIONf_bond_d0.00332683
X-RAY DIFFRACTIONf_angle_d0.80744207
X-RAY DIFFRACTIONf_dihedral_angle_d14.51412390
X-RAY DIFFRACTIONf_chiral_restr0.0484629
X-RAY DIFFRACTIONf_plane_restr0.0035692
LS refinement shell
Resolution (Å)Rfactor RfreeNum. reflection RfreeRfactor RworkNum. reflection RworkRefine-ID% reflection obs (%)
2.1-2.1750.25481340.184224325X-RAY DIFFRACTION90
2.175-2.26190.27411340.177624629X-RAY DIFFRACTION90
2.2619-2.36470.22041340.181424901X-RAY DIFFRACTION92
2.3647-2.48920.21251340.170125325X-RAY DIFFRACTION93
2.4892-2.64480.24121340.170225814X-RAY DIFFRACTION95
2.6448-2.84850.24391340.181326478X-RAY DIFFRACTION97
2.8485-3.13410.27051340.186126830X-RAY DIFFRACTION99
3.1341-3.58530.25851340.170527135X-RAY DIFFRACTION99
3.5853-4.50850.20391340.144927225X-RAY DIFFRACTION99
4.5085-19.89860.15681340.143927630X-RAY DIFFRACTION99
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL11 (°2)L12 (°2)L13 (°2)L22 (°2)L23 (°2)L33 (°2)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T11 (Å2)T12 (Å2)T13 (Å2)T22 (Å2)T23 (Å2)T33 (Å2)Origin x (Å)Origin y (Å)Origin z (Å)
10.04390.0525-0.00850.0428-0.00410.0402-0.14140.1901-0.0365-0.00220.1012-0.1161-0.0063-0.11960.04370.1576-0.0590.01490.2064-0.04370.103747.5522-14.066-15.9187
20.00230.00470.0035-0.00020.01130.00260.0212-0.0031-0.0156-0.04830.0236-0.05610.0429-0.1220.02690.1684-0.03990.02530.1533-0.07340.233348.9543-20.2105-6.9106
30.03840.0018-0.04480.2453-0.22050.4133-0.12080.0664-0.1221-0.06510.1749-0.0576-0.0649-0.03760.09860.136-0.02220.03690.1144-0.02810.148256.9957-12.7684-10.268
40.0033-0.003-0.00080.00370.00020.00240.01030.00270.0202-0.0087-0.0244-0.0171-0.03020.0346-0.00350.14830.03530.0993-0.08760.09330.371663.7739-28.09744.7515
50.0122-0.001-0.01010.0037-0.00890.0108-0.0042-0.02460.04540.1495-0.0181-0.0983-0.0023-0.0366-0.01670.16730.0205-0.0557-0.24440.01410.242255.9356-19.536316.2402
60.00260.0053-0.00560.014-0.00550.0045-0.2004-0.1415-0.0649-0.01920.0253-0.14040.0639-0.0041-0.09810.0730.14270.0095-0.24610.02140.229159.23-30.020514.9766
70.0021-0.00110.0002-0.0015-0.0010.00030.00870.01230.0180.00240.00160.0077-0.0253-0.0063-00.11490.00950.02080.1205-0.01330.283863.3877-16.97169.5171
80.01440.00140.01240.0640.00880.0101-0.1499-0.0591-0.0809-0.01750.069-0.0910.0274-0.017-0.03030.13560.01090.02150.07870.00030.195648.5793-24.519613.1741
90.0011-0.001-0.0003-0.0002-0.00040.0021-0.05710.0008-0.0353-0.01430.0182-0.02140.0389-0.0116-0.01590.2972-0.2310.07350.1129-0.17250.232345.9268-26.3215-9.3083
100.018-0.0158-0.00630.0347-0.00840.0153-0.00890.01280.0330.05630.02610.0195-0.0161-0.06670.02950.1113-0.0359-0.02440.12170.01230.142457.89566.7529-9.2159
110.00330.01380.01040.06480.03590.0294-0.02740.07910.0297-0.1916-0.1022-0.1359-0.0530.0089-0.10310.18280.0024-0.00280.10970.0080.096263.49469.4875-20.2
12-0.00190.0126-0.00730.0830.06150.0593-0.02680.08510.0791-0.0197-0.08760.02470.0515-0.117-0.06490.1327-0.11360.0046-0.2291-0.0190.160168.17934.5792-7.1486
130.00020.0021-00.00080.0005-0.0007-0.00980.09570.0303-0.0309-0.0323-0.0317-0.0013-0.0192-0.03060.1502-0.0235-0.0190.05490.01090.113563.873716.7036-7.5301
140.0581-0.04210.02970.02440.03430.06210.03980.0076-0.0532-0.0138-0.0105-0.08350.0165-0.02680.02210.12-0-0.00510.0794-0.00330.165869.51766.73990.9351
150.0873-0.0059-0.00360.0613-0.01880.0053-0.117-0.0356-0.06070.05820.09240.05620.0349-0.01510.00770.12160.0487-0.00310.0876-0.01230.093869.5405-5.515414.0216
160.0080.01040.00530.0156-0.00430.0034-0.0296-0.0998-0.00940.0626-0.0324-0.13220.00670.0266-0.01390.12620.0452-0.0670.06730.03260.205881.8305-7.237516.3984
170.0467-0.01330.04030.0202-0.02480.0371-0.0274-0.0943-0.08710.0141-0.0894-0.032-0.0083-0.0035-0.03450.12720.09250.0235-0.6611-0.11470.157674.178-3.06924.7231
18-0.00190.00570.0010.0054-0.0004-0.00130.0196-0.0385-0.01320.00460.02640.00780.07050.00130.00930.08290.1041-0.0407-0.14130.00450.177672.6377-14.94498.193
19-0.00280.01030.00770.0003-0.00260.00550.0096-0.0517-0.01930.01450.0025-0.0417-0.016-0.03950.00540.17010.03990.0116-0.1032-0.06710.083766.6733-8.43768.997
200.00340.00050.00180.0024-0.0050.00080.0505-0.02410.0027-0.01930.02-0.0957-0.0148-0.0152-00.1650.00420.03030.1022-0.0280.177671.3108-1.3042-13.8306
210.0204-0.01320.00060.0073-0.0020.0015-0.0184-0.0478-0.0019-0.01040.0426-0.0287-0.0045-0.03980.00410.16170.0008-0.0020.0692-0.00550.116249.303821.06529.837
22-0.00090.0004-0.00060.00330.00160.0016-0.05680.0049-0.0132-0.0202-0.0480.0134-0.0252-0.016400.41530.0884-0.08480.4692-0.0670.160144.630617.6669-12.673
230.0389-0.024-0.00270.00770.00690.0083-0.01450.2550.13140.0311-0.0198-0.0563-0.0585-0.0879-0.01820.13570.06-0.03390.0090.15860.266347.692231.214-4.8048
240.08420.02480.05880.04120.04640.0538-0.2096-0.0540.2250.0111-0.0742-0.09690.0002-0.0828-0.08960.1003-0.076-0.0099-0.4634-0.02010.17755.30424.17334.8152
250.01420.00510.0030.0328-0.03790.0335-0.0094-0.0120.08-0.040.075-0.0512-0.0601-0.03140.07530.1132-0.0163-0.00730.074-0.0140.167544.222923.67277.8805
260.0038-0.0043-0.00410.00610.00540.0092-0.04840.00710.06830.0019-0.01950.00770.0183-0.0356-0.02240.107-0.0264-0.06820.1423-0.23720.339659.602926.041323.8205
270.05430.00450.00010.0429-0.03980.0481-0.118-0.2590.15060.00150.1061-0.05030.05330.0739-0.03890.10410.0207-0.09650.1523-0.08060.122766.22714.28327.1409
280.01090.00020.00820.01820.01530.01690.0241-0.07210.147-0.00460.031-0.09290.0740.04420.12720.10520.0052-0.03140.0832-0.04460.177865.664515.349517.4546
290.0042-0.0009-0.00120.0039-0.00280.0027-0.02290.00380.03430.0306-0.0281-0.06760.03280.0077-0.00760.02-0.1260.0817-0.30990.30090.425559.695629.0432.922
300.02230.02480.00540.0680.00810.00080.07130.0626-0.0847-0.0021-0.05340.03490.03960.0362-0.00010.12880.030.00860.15030.01690.126230.303310.42285.572
310.00750.00520.00320.0036-0.00050.0165-0.0221-0.01890.0478-0.069-0.03330.1012-0.0413-0.0132-0.00180.16810.0227-0.0190.15310.02680.12620.218517.88093.8959
320.0421-0.00330.0410.09160.00230.0398-0.0429-0.06150.0014-0.0981-0.0023-0.06870.0295-0.0724-0.02650.0992-0.01810.00130.11060.01250.125527.756813.28515.5351
330.0022-0.005-0.00580.0154-0.00250.00050.0169-0.03790.0093-0.02920.02790.02350.0177-0.04060.02350.12330.0184-0.05670.17320.0050.13520.8994.46019.2488
340.0188-0.00280.0225-0.003-0.00810.0067-0.0088-0.07970.0341-0.0571-0.06330.03710.0143-0.040800.14090.00270.00460.15450.00690.112829.62076.677320.5728
350.0081-0.0001-0.009200.00050.0131-0.09550.00030.0286-0.0241-0.0403-0.02150.0169-0.0045-0.00080.1281-0.0039-0.01810.1222-0.01850.108340.623812.820824.3037
360.01870.0032-0.01010.0022-0.00940.00850.0909-0.22420.00140.0594-0.0715-0.01760.0710.0374-0.04760.19760.0022-0.05170.30010.04020.120643.56835.858740.7142
370.01720.00090.00970.0009-0.00510.016-0.0691-0.00940.02410.0066-0.025-0.0748-0.0594-0.0392-0.00260.1238-0.0066-0.00420.15190.00860.114934.94588.622829.0187
380.1907-0.04520.11270.0788-0.01470.32480.0758-0.20040.0070.00790.0185-0.0362-0.03160.02050.08980.10410.0104-0.01150.1665-0.03820.115544.776415.060628.233
39-0.00080.0002-0.0015-0.00250.00030.0007-0.0784-0.03690.01580.01670.00190.0265-0.0006-0.0389-00.1622-0.0122-0.02810.1310.00040.19827.336622.760415.8721
400.00260.00160.00710.0010.00830.0107-0.04940.0497-0.05040.00420.01740.00340.01360.109-0.00010.1299-0.0074-0.00860.1081-0.01130.143233.0485-14.76445.5977
410.00240.0047-0.00020.0004-0.00230.00090.0312-0.005-0.0045-0.0199-0.0012-0.0253-0.0359-0.003700.47650.01840.00480.24680.10030.311128.24771.8701-10.3303
420.03480.0202-0.00850.0293-0.00950.01590.07140.10530.0311-0.0628-0.060.02690.0202-0.10440.03180.13520.0326-0.06660.17670.00570.163920.0347-11.4856-6.0815
430.02310.00830.0165-0.00080.0101-0.00710.0156-0.0008-0.0764-0.00580.0083-0.1008-0.0277-0.095800.128-0.00650.01040.1208-0.01040.156927.1343-14.25836.4204
440.0354-0.00870.00550.0214-0.0290.07420.03440.0867-0.0574-0.0263-0.04680.0198-0.0337-0.0188-0.00550.1482-0.0102-0.00560.107-0.03240.11533.8617-15.7181-2.0512
450.0004-0.0003-0.00220.0013-0.00060.00140.0207-0.0025-0.00620.00390.0363-0.02350.047-0.0287-00.20510.01690.00360.15380.0330.23231.6284-25.258720.6931
460.07080.0229-0.02490.0271-0.03290.0630.0652-0.0723-0.0140.06110.0249-0.0332-0.08370.0710.07940.15110.0276-0.00910.15180.02730.170940.502-12.708825.6954
470.05490.0090.00710.03740.0083-0.0021-0.0589-0.0703-0.17120.0857-0.0113-0.10960.0086-0.0617-0.01040.14910.04560.01220.12830.07810.225435.0073-20.05428.56
480.13160.07720.06780.06450.04980.04930.01820.0077-0.07010.1414-0.00170.0061-0.0186-0.05270.03080.12810.0198-0.00120.12630.02510.090932.3447-8.616426.1157
490.0001-0.0006-0.0020.0020.00050.0008-0.05140.0009-0.0460.05750.0060.0284-0.03770.029500.15970.0120.03520.15430.00190.196918.319-11.35348.4756
500.01210.0033-0.01250.0058-0.00490.0111-0.01850.04260.02090.01050.1010.12460.0164-0.02820.00390.1337-0.03-0.02580.1870.02590.1456-8.332211.627822.3686
510.0019-0.01390.00890.0076-0.0053-0.0005-0.02380.14470.0025-0.02160.0304-0.0582-0.068-0.0746-00.18190.0009-0.00580.21340.01620.1435-4.307518.982712.7741
52-0.00160.0048-0.02670.0046-0.00020.0011-0.01440.0274-0.0380.0138-0.0492-0.0421-0.03770.0132-00.1326-0.0013-0.00870.14430.0010.10441.021614.838426.2579
530.00560.0072-0.00690.01080.00930.0090.04210.04450.05270.10910.04160.00980.0355-0.1301-00.16710.03040.00280.19020.02540.154-9.204718.789827.1778
540.00180.001700.00010.00210.0009-0.0352-0.0179-0.00250.00210.0419-0.0063-0.0162-0.008300.1793-0.0154-0.01260.2438-0.04030.195510.847218.025241.9492
550.0048-0.0037-00.0057-0.00420.00070.1054-0.1233-0.0382-0.05840.02170.04370.05850.035800.1457-0.0003-0.00720.2044-0.00020.12436.51784.478536.2699
560.0033-0.00060.00160.0023-0.00230.0021-0.02290.0060.00110.01250.01050.03410.0087-0.0027-0.00040.4798-0.15890.08040.45070.07050.19854.70551.3859.8354
57-0.00340.00950.00040.0746-0.01170.03610.04150.0144-0.01250.14850.0974-0.11710.03820.07360.03560.1979-0.0109-0.04460.2814-0.01290.129316.49987.760750.868
580.00310.0147-0.00350.0379-0.00780.0027-0.0959-0.0625-0.05990.0596-0.0477-0.05620.0381-0.0003-0.00440.140.00470.0120.1708-0.01590.12789.02519.523838.2804
590.02210.00480.0019-0.00030.0024-0.00020.0043-0.0439-0.08190.0394-0.0412-0.09390.01450.0128-0.01520.13850.022-0.04140.21850.02850.133514.485-1.924839.6884
60-0.00510.0003-0.00070.00810.00580.00260.0899-0.0056-0.0366-0.0546-0.0124-0.0551-0.001-0.045900.1761-0.0216-0.00770.21210.02790.16095.51130.190940.4433
610.0017-0.00010.00190.0027-0.00070.00010.03130.02310.0087-0.0226-0.0264-0.0341-0.00090.0424-00.1679-0.0061-0.00180.18390.01240.16727.472112.837119.8004
620.0072-0.00680.00470.0085-0.00640.00250.029-0.0270.0252-0.0131-0.02290.072-0.0172-0.026-00.17450.0482-0.00530.24640.00370.1534-25.329515.551140.9797
63-0.0001-0.00050.00250.00110.00030.0025-0.00460.0271-0.0322-0.0354-0.0343-0.0002-0.01490.0019-00.4004-0.0036-0.10290.53330.06330.199-24.702612.987417.8884
640.0085-0.0028-0.00520.01930.00450.00820.06730.05970.1237-0.1151-0.00820.16020.00550.00390.01440.21930.1077-0.05940.27830.11890.2402-30.041924.779426.2354
650.0036-0.0089-0.00170.0004-0.00990.0022-0.01810.05890.0414-0.01680.03850.0279-0.01890.014200.14250.05280.00720.1530.00520.1606-22.603822.635937.4907
660.02270.0066-0.00120.0137-0.00340.0145-0.0133-0.01430.1763-0.0188-0.03460.16950.05090.0408-0.00210.1650.0472-0.01890.2066-0.03680.1718-30.652115.23138.2653
67-00.00160.0023-0.00020.00040.00290.0111-0.0130.0416-0.007-0.0060.0098-0.0091-0.02-0.00020.1254-0.0110.0180.2902-0.15110.2704-21.193623.226956.7827
680.0406-0.00070.0090.00640.01440.0077-0.0242-0.08540.00560.0150.0151-0.0304-0.07780.03690.00550.1839-0.0092-0.010.201-0.01840.1219-10.125511.576455.4104
690.0102-0.0034-0.00230.0071-0.01670.01450.025-0.1250.0789-0.05890.0070.0308-0.09540.05380.0024-0.0407-0.2718-0.26680.2494-0.3506-0.1334-9.289219.849264.7444
700.0968-0.04860.0790.0194-0.03910.06690.0261-0.11670.0178-0.0480.0279-0.0302-0.0673-0.08430.03530.1724-0.01440.01970.2416-0.07790.1631-17.163618.861253.0716
710.0258-0.0021-0.00110.00890.00540.0019-0.0792-0.04040.05550.01960.0101-0.0278-0.0148-0.0589-0.02660.1090.00650.00440.1318-0.05430.1328-10.682822.416948.0284
720.0009-00.00020.0013-0.00060.00140.0507-0.0317-0.0145-0.00090.0234-0.03860.03640.04210.00890.1679-0.021-0.02610.2591-0.07240.1688-1.975419.276351.8057
730.01590.03350.01160.0167-0.0060.00420.1525-0.10970.1674-0.0739-0.00030.0759-0.00690.03860.00020.20110.0294-00.1797-0.01380.2222-13.614420.329943.5531
740.0431-0.00780.00250.02170.01990.00980.05310.03630.0667-0.0616-0.0421-0.03490.0185-0.05120.02170.15990.0251-0.01650.15630.0120.105-34.577-2.768332.2003
750.0086-0.00040.00010.0441-0.01460.01110.10520.07070.0767-0.1789-0.12390.075-0.0496-0.07960.00770.06650.1848-0.24360.306-0.04990.2634-46.8379-1.78629.4908
760.01940.00250.0122-0.00050.0020.00260.0346-0.0215-0.0543-0.0486-0.0084-0.0003-0.00150.005500.15120.0071-0.03020.1914-0.03370.1584-39.1797-3.650341.7566
77-0.0014-0.00130.00270.00180.00240.00250.01370.0415-0.0364-0.0267-0.02620.04760.0327-0.057300.182-0.0096-0.04350.2044-0.01950.1834-38.7692-15.977534.9636
780.00530.00260.00040.00520.0020.00050.0996-0.05760.0701-0.0413-0.0336-0.01330.00570.0196-00.20770.04140.00610.19860.00650.1523-34.1421-6.996532.9723
79-0.0002-0.0014-0.0005-0.0012-0.00120.01140.0564-0.0237-0.00110.0168-0.08390.07060.04520.0202-0.0160.199-0.1158-0.00050.2733-0.156-0.0436-36.4561-9.868158.6007
800.00120.0017-0.00290.00430.00570.00450.0295-0.03730.01540.0440.0201-0.00520.00660.002400.17370.011800.2213-0.01720.1493-29.38081.629952.5759
810.00740.00490.00720.00390.00730.00970.0050.0047-0.0016-0.0111-0.0075-0.0389-0.0105-0.0065-0.00190.42080.148-0.22540.45120.07430.4311-12.6559-8.529865.977
820.0566-0.01340.01610.0311-0.02740.0405-0.072-0.1258-0.01550.1587-0.19660.0190.02590.0051-0.10980.0153-0.2445-0.25810.3667-0.1934-0.1997-27.9279-4.018469.6148
830.00060.0011-0.0012-0.00060.0006-0.0005-0.014-0.03070.035-0.0093-0.08510.02170.02110.0306-00.1551-0.0286-0.00890.2985-0.05380.1761-36.7616-1.183557.0131
840.0009-0.0005-0.0005-0.00070.00220.00910.0246-0.03980.03390.00250.0061-0.026-0.0142-0.0011-00.2006-0.0016-0.01240.3356-0.02660.1881-25.5884-11.877354.4314
850.00730.0046-0.00270.0058-0.01040.00770.0303-0.03510.0429-0.0179-0.02050.0457-0.0584-0.01820.00660.1535-0.03180.00250.3282-0.09870.162-33.61463.286455.3186
860.0642-0.00560.04980.0066-0.01090.0430.0813-0.1099-0.01790.0156-0.15660.0326-0.11990.1037-0.03030.1868-0.0329-0.01560.2887-0.04250.1458-25.40935.485358.2002
870.0004-0.0015-0.00060.0062-0.00410.0071-0.0125-0.0311-0.01160.0147-0.00870.0604-0.03140.0427-0.00010.14550.0178-0.03920.266-0.08720.3601-45.03653.578442.8395
880.04510.0597-0.00750.08730.02480.03010.020.011-0.0351-0.0379-0.0382-0.057-0.0916-0.0345-0.01270.21410.0389-0.00690.1255-0.02630.106-23.098-16.302824.576
890.0299-0.0097-0.02810.015-0.00530.0127-0.00510.1408-0.0408-0.0031-0.01890.05670.0834-0.14040.02460.198-0.0223-0.00690.1939-0.06160.1176-29.971-24.045817.0768
900.01260.01750.01250.00750.02190.0261-0.0405-0.05420.0606-0.1027-0.0066-0.07220.0935-0.1347-0.00180.16710.00940.0130.16840.00420.1658-23.1853-25.700830.144
910.0188-0.00060.00610.020.01350.00940.00520.0243-0.0145-0.0687-0.0005-0.0703-0.02260.003-0.00260.2182-0.00780.03190.1432-0.04220.1074-13.6847-24.791620.8264
920.01070.0079-0.0050.0033-0.01180.00230.0321-0.0514-0.0483-0.0101-0.0021-0.0352-0.0695-0.002-00.1817-0.0137-0.02540.15320.00220.1545-18.7196-18.04625.392
930.00540.00060.00080.0009-0.0009-0.0005-0.0076-0.0120.0030.0109-0.0772-0.03320.0248-0.0003-0.01720.2458-0.0259-0.00190.14620.07980.2388-15.8282-34.34843.7417
940.0337-0.0437-0.03310.05650.04460.0304-0.00020.0411-0.01870.0498-0.0682-0.0659-0.08660.0062-0.04240.154-0.0604-0.04110.16590.04380.1251-14.8648-20.065551.4751
950.0404-0.00710.02890.03970.01740.01630.0082-0.06730.01190.06580.09830.03980.11980.00840.05290.1030.0367-0.10750.23960.21650.1008-14.5456-30.60158.3568
960.0420.00750.00420.01520.03330.092-0.0582-0.031-0.00350.0228-0.0163-0.08910.0053-0.0886-0.01940.1175-0.0304-0.01150.17760.04790.1856-20.8249-27.035745.61
970.0050.00590.00030.03030.00210.00040.0062-0.05760.0070.0141-0.06840.0473-0.0770.03-0.01020.1118-0.0018-0.0110.28940.00990.1125-25.8236-21.10355.4509
980.01860.0174-0.00520.04670.03350.0478-0.1226-0.0440.0079-0.0656-0.0287-0.02410.0301-0.0107-0.08710.1425-0.0295-0.02160.1608-0.01440.1307-25.5949-22.554441.1955
990.0047-0.0032-0.0012-0.00080.00030.00340.0018-0.0062-0.02360.00640.0164-0.085-0.0708-0.0024-00.16170.00510.00060.1965-0.00230.11151.2978-8.735324.0749
1000.00370.0026-0.00280.0261-0.01640.01080.0049-0.0340.00990.03450.0280.0221-0.00720.00060.00780.14760.0347-0.13670.30930.04090.304-17.8579-6.478710.1222
1010.1188-0.0050.04470.1867-0.19410.3599-0.13580.0274-0.0331-0.1291-0.15890.0738-0.0361-0.0204-0.1550.1882-0.0354-0.00960.1965-0.11580.1768-2.9828-11.98076.9475
102-0.00020.0066-0.0005-0.00080.0077-0.002-0.01630.0163-0.0097-0.07710.0090.08420.03410.0194-00.169-0.02410.01250.1784-0.01550.1754-0.8445-16.026620.4069
1030.0043-0.0060.00060.01070.00240.00120.0407-0.00390.0218-0.0374-0.0046-0.04910.03380.0872-00.12580.01130.04330.12370.01070.13945.7431-9.975121.5094
104-0.0015-0.00260.00210.00520.0036-0.0013-0.03610.02420.01-0.0190.0122-0.0370.0049-0.0224-0.0060.20870.00360.00210.1510.02180.10883.0832-2.015715.8761
1050.09070.0394-0.03280.27940.11480.2184-0.0539-0.026-0.1261-0.0682-0.0489-0.0620.07260.0489-0.17810.1366-0.01520.01510.1690.03880.16975.4343-10.218427.4872
1060.00430.0021-0.00710.0014-0.00280.00510.05690.0215-0.0495-0.03580.04370.01780.0494-0.017600.16690.00190.02320.15850.03810.2241-0.2362-19.228735.1636
1070.0017-0.0019-0.00140.00030.00010.00130.0170.0090.02960.0068-0.00720.02950.01910.00400.4519-0.144-0.05280.62010.01940.25746.8058-11.969556.2483
1080.0634-0.02560.01020.2145-0.00450.03360.0262-0.1969-0.12480.1161-0.121-0.15440.05160.0906-0.04630.1767-0.0216-0.01230.34620.16610.297413.0951-22.866446.6399
1090.0138-0.0063-0.00190.00210.00540.0014-0.0569-0.0202-0.03940.0128-0.1170.0014-0.01660.0819-0.04890.17090.0078-0.00150.15340.08180.26377.7626-16.368735.2319
1100.01070.01140.00230.0014-0.01480.02830.0815-0.1598-0.2414-0.0628-0.12410.0183-0.010.0285-0.03040.14140.01970.01520.19430.08010.2102-0.4346-23.620839.4824
1110.00080.0015-0.00030.0034-0.00680.0142-0.0078-0.01590.0147-0.00560.0004-0.0060.0440.0443-0.00440.3045-0.00940.0830.1127-0.01850.21470.3862-22.104316.7811
1120.00320.02840.02210.03590.00810.0105-0.0752-0.0352-0.05370.2140.2062-0.4244-0.05650.04280.03730.0334-0.2183-0.3720.0072-0.48720.1575-38.122135.877268.6357
1130.0125-0.00570.02290.04020.00390.0195-0.0286-0.0020.0054-0.0232-0.0045-0.0186-0.00190.0785-0.03670.1369-0.0226-0.00490.2882-0.21960.3434-42.412135.016660.9538
1140.0106-0.00630.01130.0018-0.00780.0022-0.12660.0032-0.00140.0844-0.0001-0.1489-0.03310.0049-0.03290.20270.042-0.13140.3611-0.20680.2329-44.281527.645266.6704
1150.0218-0.02510.02030.0781-0.04950.0340.0659-0.02330.0002-0.04460.02190.04020.0207-0.02750.01360.2761-0.03450.08770.3349-0.1180.2168-41.235130.817342.312
1160.0957-0.054-0.05290.121-0.09820.18510.2824-0.07720.1282-0.1710.12890.011-0.04460.07440.15090.3163-0.11630.06310.2609-0.12890.1369-55.790437.703842.4729
1170.02620.0009-0.01230.0013-0.00180.00970.08820.01470.0172-0.15190.01870.031-0.07310.04020.06230.4582-0.13030.36980.1714-0.202-0.1421-49.257936.859531.8029
1180.0941-0.03970.040.0149-0.01640.02710.1001-0.02090.1089-0.03360.1379-0.0625-0.25380.10890.06250.2348-0.10020.1010.2528-0.09230.2473-45.579937.655745.9135
1190.00010.0027-0.00220.00460.00960.00850.1-0.06950.0839-0.0711-0.00530.0199-0.04380.05270.01750.6769-0.19530.244-0.052-0.07030.2418-50.870648.268640.7363
1200-0.0037-0.0010.0015-0.00070.00210.1018-0.13070.0639-0.08760.0035-0.0174-0.03910.0578-00.3293-0.07490.03860.229-0.04890.1953-54.725642.51146.5743
1210.003-0.00310.00020.0204-0.01010.0252-0.04860.01930.011-0.0013-0.0646-0.0113-0.0164-0.0039-0.02020.0844-0.0425-0.00760.4418-0.35360.7614-33.85241.809359.5962
1220.00830.0219-0.00390.0176-0.02290.0366-0.149-0.1328-0.05070.05480.13720.02810.02190.0756-0.01160.25470.12460.01150.29590.03650.2294-55.06717.669578.8175
1230.00630.0007-0.00110.00020.00330.0034-0.0268-0.04930.00790.0279-0.0210.0535-0.02850.0344-00.22360.0560.0290.3612-0.0130.2458-54.818715.025268.2796
1240.0059-0.0010.00540.01660.01160.0027-0.1124-0.0608-0.104-0.03390.2260.0170.05140.005400.27440.08080.04690.28710.04810.2633-64.786716.179873.6502
125-0.00030.00220.00130.00780.00380.0030.0052-0.0054-0.02920.0480.0107-0.00960.0230.01230.00160.29610.02630.25590.1394-0.17260.5467-65.00286.175153.6579
1260.01380.0041-0.03450.0120.00760.024-0.09990.0089-0.16010.0175-0.05950.2924-0.03640.1176-0.01750.16330.0564-0.04370.1589-0.16840.4045-64.630215.454242.7879
1270.00270.00460.00390.0148-0.00480.0055-0.0090.03330.03140.03130.04020.08520.09280.0650.00160.21340.01410.08110.2392-0.07820.417-62.267812.341853.1465
1280.0011-0.00660.00520.0161-0.0048-0.00060.02530.0159-0.1162-0.07390.09020.1242-0.01780.09470.00020.21680.01220.03140.2593-0.06740.243-53.603917.554147.5415
1290.07430.05980.11520.11050.13010.1853-0.1913-0.0312-0.0642-0.09-0.1240.0963-0.00760.0988-0.02660.190.1020.0540.35920.0220.2696-55.208418.876257.3463
130-0.0030.01030.00520.0269-0.00450.00370.021-0.04160.0163-0.0299-0.01430.0202-0.03040.0409-00.1979-0.00550.00980.34610.00090.1648-74.519231.376780.5288
1310.0058-0.0166-0.00790.11440.06040.0414-0.0875-0.0291-0.08150.1693-0.09640.0919-0.00030.0037-0.02590.23930.02460.030.26370.08360.1915-81.180125.730687.0001
132-0.00010.0008-00.0013-0.0004-0.0003-0.005-0.05190.04470.00290.01760.0097-0.00360.009-00.29060.08830.05480.32710.09330.2921-70.622122.63876.363
1330.0110.0142-0.00380.0172-0.0051-0.0011-0.02670.0172-0.00850.0082-0.04090.0291-0.0196-0.025300.2070.02510.0370.23490.010.2042-85.349234.370980.2947
1340.00330.0014-0.00080.0024-0.00340.0019-0.01190.00640.00230.00650.00960.00550.0116-0.0107-00.17660.02610.00460.2957-0.01980.2472-78.141334.918276.6729
1350.00070.00090.00140.0019-0.0003-0.0007-0.03450.03720.00160.02220.00110.00040.01360.0059-00.151-0.03470.04330.3573-0.07840.3324-95.359324.471163.0814
1360.0174-0.01970.0070.02790.01880.0777-0.05080.1289-0.1321-0.0294-0.08520.10810.0123-0.1109-0.11290.19210.0047-0.02940.2556-0.11430.2399-88.137722.021751.4008
1370.00860.00590.00440.0017-0.00050.0003-0.0780.0677-0.04330.0016-0.12320.0076-0.0087-0.0928-0.00020.1914-0.00730.03050.2558-0.03730.3269-88.147524.454862.1982
1380.0139-0.0016-0.00120.0058-0.00930.0018-0.06470.0801-0.23570.1025-0.0685-0.00910.0642-0.006300.2454-0.00520.05430.2459-0.04340.2592-80.001717.442857.8507
1390.0027-0.00160.00090.0025-0.00190.0029-0.0170.00750.00060.01320.007-0.02450.01760.00900.28890.11380.13310.24270.09670.3093-82.194117.046280.5425
1400.0149-0.00510.00970.01440.00480.0121-0.0457-0.00480.033-0.05030.0168-0.0067-0.08350.0416-0.00820.2757-0.03110.0470.2383-0.02180.1263-76.077454.67170.0338
1410.0023-0.00070.00010.0012-00.0002-0.02710.025-0.0214-0.0072-0.0092-0.0086-0.0036-0.005300.57460.0263-0.10890.50860.00660.4843-66.087645.225889.1325
142-0.0010.01240.01250.01960.01870.0113-0.0174-0.10020.02540.02390.01790.0538-0.02180.0633-0.01080.3367-0.01770.0910.3332-0.03090.1691-76.40757.206187.8328
1430.020.00460.0010.00540.00840.0068-0.0621-0.09420.0107-0.061-0.08620.0261-0.09250.0435-0.0010.2277-0.01810.04570.2791-0.00990.159-81.837751.903275.6383
1440.0006-0.01330.0020.015-0.00580.00390.0439-0.1432-0.0851-0.0570.11050.0287-0.14480.0716-00.2461-0.04050.02910.2483-0.04960.1844-72.397458.529673.1775
1450.0030.00120.00060.00040.00180.00010.00140.0114-0.0139-0.01020.0033-0.0074-0.02850.0136-00.27450.0194-0.02610.3101-0.0050.3112-89.526759.371357.5213
1460.00610.00020.00290.0004-0.00070.00260.1046-0.0067-0.0346-0.04970.037-0.02330.0399-0.02580.00010.21330.00230.0190.28370.03280.1457-86.031245.376862.7881
1470.00090.00090.00160.00160.00290.0024-0.01280.00930.0038-0.0007-0.017-0.0198-0.01320.018900.3685-0.08460.12650.543-0.16040.378-83.927745.595739.1037
1480.00670.00140.0026-0.0003-0.00330.0047-0.0118-0.00150.04-0.08220.07270.0424-0.0136-0.030500.2580.0185-0.01270.34990.01510.1872-94.924450.577148.9924
149-0.0001-0.0061-0.00320.0064-0.0008-0.0017-0.07020.0052-0.022-0.05660.0365-0.0312-0.0719-0.0181-00.2601-0.00490.01470.31280.02340.2014-87.62652.81759.4155
1500.0176-0.006-0.00150.0304-0.01740.00990.1359-0.0914-0.0845-0.18250.03250.1541-0.0587-0.034-00.23070.0042-0.00310.2880.00860.2617-90.086342.139759.6977
151-0.0001-0.0005-0.00040.0021-0.00070.00230.0554-0.02950.0172-0.04370.00770.02840.0271-0.0275-00.2163-0.02730.0550.3077-0.02350.2212-87.729452.642279.679
152-0.00070.00560.00160.04350.00280.0011-0.0044-0.0891-0.0576-0.01640.0403-0.141-0.01110.03920.00620.2781-0.24250.04160.2813-0.4373-0.0341-54.146853.14670.9102
1530.0158-0.0079-0.00990.0144-0.00920.02190.0424-0.04730.00150.0934-0.0028-0.0419-0.00620.0270.01830.3364-0.17160.01840.2907-0.19040.2097-48.68662.866776.8806
1540.002-0.0041-0.00130.0046-0.00160.0089-0.0183-0.05840.01640.00210.0533-0.0085-0.04530.0751-00.2294-0.08370.06130.3171-0.10290.2425-51.359264.354461.3922
1550.0020.0017-0.00050.00020.00170.0002-0.0523-0.028-0.0365-0.0054-0.05450.003-0.01280.0324-00.2947-0.11080.15090.3544-0.10430.2844-63.342257.892570.549
1560.0010.00240.00130.00690.00270.0012-0.03370.02030.00370.00760.0557-0.0686-0.05570.0136-00.2033-0.08360.07680.2238-0.08090.2129-50.069258.744660.0936
1570.01170.01010.00140.00460.0010.00320.010.0201-0.00810.01140.0022-0.06470.01920.0004-0.0050.1599-0.28430.0150.3557-0.36120.2963-42.550953.337264.1401
1580.00910.00090.00570.01880.00150.0398-0.00980.00680.0171-0.02330.0589-0.0824-0.0046-0.01210.00390.3458-0.12650.0330.2729-0.08510.2025-51.711851.589766.9331
1590.00050.0002-0.0043-0.00060.00040.00140.0041-0.012-0.00970.01920.01790.028-0.01750.036900.4728-0.1210.13970.2745-0.06210.3284-55.825963.135144.6013
1600.02770.0155-0.01140.0125-0.01440.01130.0213-0.0120.0795-0.0450.0788-0.02320.043-0.0610.03160.4049-0.06980.03890.1574-0.05210.0877-68.33152.304646.2568
1610.01440.0023-0.01150.00070.01570.01530.0280.11070.02590.0087-0.012-0.0094-0.0638-0.0217-0.00180.433-0.00660.04870.2516-0.00150.1449-68.36660.82337.0659
1620.01360.00510.00090.0028-0.00760.0096-0.01520.0006-0.0216-0.0222-0.0264-0.0166-0.0158-0.0089-0.02230.5047-0.05630.19520.0796-0.16950.1424-60.569759.194448.6631
1630.01270.0034-0.00620.00930.00170.01060.1329-0.04940.0528-0.06370.0095-0.0043-0.0057-0.0982-00.2762-0.03330.03870.2104-0.0240.1844-71.810559.181851.1914
1640.00780.00190.00040.00670.00840.01030.0090.00620.0010.0020.03090.01590.01450.02170.01010.3237-0.08440.10960.2817-0.15630.3524-57.705667.497767.9982
1650.00590.0089-0.00960.00170.00010.00840.04080.0376-0.044-0.00780.0263-0.0994-0.00420.03030.00820.20760.01340.04780.07490.00480.3417-137.468222.591478.4305
1660.0659-0.011-0.03540.00680.00850.0183-0.06210.1185-0.03770.06870.04280.01960.1265-0.0335-0.00050.237-0.03360.0570.1939-0.07220.5557-143.171512.04174.5926
1670.00110.00110.00290.00110.00010.00220.0442-0.022-0.03380.0128-0.0169-0.03520.00640.01110.00470.2867-0.02580.093-0.01040.04730.4387-138.467813.451388.6047
168-0-0.0001-0.00130.00080.00380.01150.02260.0068-0.01410.0076-0.0342-0.02580.01140.00930.00010.2485-0.00210.04460.2816-0.01290.267-145.170326.123184.4947
1690.00080.00720.01540.0198-0.02270.0136-0.19760.0751-0.18830.09940.0513-0.0036-0.03540.0143-0.04880.2383-0.0090.120.031-0.08990.4275-130.766816.846481.4645
1700.0063-0.00140.00210.00670.00040.0026-0.0003-0.0076-0.0292-0.02440.0255-0.0084-0.0150.03310.00810.43430.10440.12720.13840.13550.3543-129.302613.4838103.7662
1710.00650.0058-0.00990.0225-0.01350.0196-0.0248-0.0432-0.00620.0106-0.00210.0713-0.0124-0.0128-0.00910.1965-0.00070.03010.14930.0710.1737-137.817225.568199.7615
172-00.0005-0.00050.0028-0.00060.00730.02280.02860.0115-0.0045-0.0015-0.0024-0.0019-0.010900.5871-0.0766-0.05450.4346-0.020.3046-121.560835.1763112.9533
1730.01220.0081-0.00350.00450.00570.0024-0.0864-0.109-0.06570.11070.1020.0210.0077-0.01560.01040.27350.1891-0.00170.2830.46460.1552-130.702622.1509115.6368
174-0.0013-0.0007-0.00060.00380.00040.0017-0.0071-0.0066-0.01840.0391-0.003-0.00920.0338-0.0105-0.00160.3110.09050.1140.17820.15510.3706-137.59416.9613102.6674
1750.00020.0001-0.0017-0.00090.00080.00130.0064-0.0409-0.0016-0.0084-0.00270.0071-0.0187-0.009800.26940.02430.04890.27620.0670.2998-124.077623.7744100.3132
1760.0131-0.00830.00750.0123-0.00320.0035-0.2113-0.1596-0.10870.06460.17330.055-0.03730.019500.27280.040.0270.23630.07120.2328-139.968527.6057105.1502
1770.00030.0005-0.00150.00040.0015-0.00160.01620.0083-0.01540.00740.00140.02050.0339-0.0144-0.00070.3276-0.10240.20260.1384-0.11110.5123-146.297613.862787.3369
178-0.002-0.0051-0.005-0.00060.01180.0170.01380.0321-0.008-0.04220.06550.07-0.01750.021800.2107-0.04070.01630.2913-0.05760.2358-121.972228.73769.3605
1790.0285-0.00740.0160.0368-0.01180.012-0.01730.0364-0.0491-0.1776-0.01610.00950.05320.01720.02810.3318-0.1640.14260.209-0.510.2576-117.006121.463761.247
1800.00060.00910.0010.00420.00290.0026-0.01830.0388-0.0005-0.0220.0315-0.0120.05820.03800.2265-0.06030.07620.2707-0.06650.3447-114.15322.90374.5712
1810.0043-0.0011-0.00370.005-0.0086-0.001-0.00160.0825-0.0801-0.1045-0.0246-0.0078-0.08910.047700.2491-0.0250.05930.2455-0.04620.2265-110.840832.480169.2792
1820.00960.0129-0.0117-0.001-0.02060.0137-0.1861-0.0037-0.0556-0.0515-0.0695-0.04240.05640.0014-0.00020.2125-0.01530.03510.20920.00820.2285-109.64431.169580.0245
1830.00670.0139-0.01030.0019-0.00590.0066-0.0008-0.0203-0.18380.0702-0.03710.0903-0.0769-0.0056-00.2783-0.0160.01610.1933-0.00460.1954-113.267129.622895.8944
1840.0148-0.0063-0.0087-0.0020.00460.0039-0.0171-0.0409-0.21420.1205-0.1685-0.0175-0.09410.0967-00.2683-0.00420.01810.31370.06570.2638-103.632525.584398.857
1850.0009-0.00010.0002-0.00020.00060.0001-0.00450.0057-0.0018-0.0156-0.0140.0254-0.0006-0.0096-00.2186-0.0544-0.02970.25970.03280.3288-107.961937.01490.5586
1860.01320.0187-0.00110.00970.0043-0.0013-0.0597-0.1053-0.2974-0.0009-0.10290.04250.02210.144700.2320.0390.04460.2270.04140.2642-115.279422.695895.8415
1870.00080.00180.00110.01990.01110.0061-0.0060.00420.00130.0405-0.016-0.01020.0318-0.0176-0.00740.22580.01920.16950.1998-0.12560.3764-113.476916.241973.77
1880.0148-0.02660.01840.0255-0.02930.0225-0.01130.14950.0297-0.0296-0.03040.02490.0139-0.0953-0.02240.2008-0.0353-0.0250.3347-0.01840.1283-122.405950.127160.818
1890.0054-0.0003-0.01130.00090.0049-0.0011-0.0920.09720.0272-0.0043-0.07690.02590.0160.0462-0.00010.2738-0.0013-0.01530.2539-0.01220.1783-114.652551.547668.4179
1900.0019-0.0052-0.00410.00010.00010.00150.03660.15790.0254-0.04860.03980.0249-0.06760.000300.19090.0098-0.01680.22960.03070.1863-124.071957.4869.8038
1910.0015-0.0021-0.00160.00170.0023-0.0005-0.05450.00890.01160.0098-0.03240.0065-0.0176-0.00600.2021-0.03720.0340.2492-0.00950.3189-107.029463.031983.6364
1920.01520.0057-0.0085-0.00220.0036-0.00030.1198-0.0838-0.01290.035-0.0046-0.00640.01850.00300.2176-0.05870.02750.2871-0.07370.1858-110.726949.938892.7942
1930.0140.0019-0.0230.0361-0.02490.04360.1426-0.02820.04460.1303-0.0234-0.04710.03490.04830.00380.1725-0.0481-0.01670.3185-0.03080.1771-100.558356.902595.5159
194-0.0039-0.0025-0.00580.0019-0.00090.0044-0.11160.01790.070.064-0.02060.0528-0.04830.0395-00.2237-0.00080.01920.2428-0.0430.2114-109.65656.349784.3909
1950.0037-0.0026-0.00910.01470.00110.00550.0055-0.0202-0.07590.011-0.1071-0.0521-0.07750.083700.21430.00240.03240.22590.00190.2099-103.161445.992785.8347
196-0.00510.00460.0069-0.0045-0.00060.00580.02930.0375-0.01490.0025-0.10070.07840.05530.009700.2021-0.0080.02210.2597-0.00910.1834-109.782747.5577.4286
1970.02390.00860.03260.01340.01340.0177-0.14520.17080.1806-0.00520.16770.07090.02970.03150.0190.16460.0941-0.2190.08510.2636-0.0972-145.697157.422869.6514
1980.00380.0014-0.00440.0026-0.00870.0012-0.12320.05630.01830.02940.02910.0034-0.0833-0.009600.19590.0058-0.00450.17310.03930.2271-139.413862.852577.1951
1990.0176-0.0378-0.00740.05810.02050.0075-0.03430.02810.11060.0320.093-0.00240.0051-0.07450.02340.21090.027-0.0460.18980.040.1482-148.180456.171380.415
2000.0102-0.0045-0.00740.00760.00470.0063-0.0693-0.01940.05820.0119-0.02340.03650.0341-0.016-0.00850.2257-0.0039-0.00450.1746-0.08850.4279-139.906470.418795.2583
2010.0459-0.01270.0306-0.0013-0.00390.03860.0403-0.10470.18460.02340.0123-0.02310.02980.01340.0310.2904-0.0269-0.0310.2166-0.08960.2418-128.011366.009101.3859
2020.0026-0.001-0.00290.0033-0.0023-0.0015-0.0099-0.0378-0.00270.0452-0.0583-0.0498-0.0080.007700.25770.01060.0050.2145-0.01070.252-135.488365.420493.2637
2030.009-0.00890.00570.0295-0.00810.030.0468-0.04820.0890.0390.09040.0452-0.01290.09910.05890.2029-0.0113-0.03370.1497-0.04460.2189-124.318964.385490.77
2040.0057-0.004-0.00080.00420.00250.0029-0.01090.02460.02280.0056-0.01290.0002-0.01190.03240.00740.27420.0143-0.08040.19860.09380.3537-138.525368.979174.3695
2050.039-0.0461-0.02410.0470.04250.0156-0.06860.078-0.0331-0.0194-0.00240.04880.0930.0421-0.00530.1911-0.0541-0.02760.20240.00510.1471-157.464636.149278.6675
206-0.0019-0.0043-0.00390.0003-0.0027-0.0023-0.0783-0.07270.0711-0.0449-0.1497-0.01040.0354-0.0525-0.00040.22280.0026-0.0260.15340.02160.197-155.813742.003788.2991
2070.0155-0.01010.00030.0094-0.00370.00590.0056-0.0057-0.1353-0.0293-0.01280.02670.00070.035300.2136-0.01450.02620.1657-0.00720.2028-152.424531.041487.276
2080.0019-0.00250.00070.00280.00220.002-0.00960.004-0.01160.0151-0.03050.04760.03440.012300.26150.03760.01970.20750.00310.147-152.897239.7544109.0799
2090.02710.0365-0.00080.0157-0.00480.0078-0.0856-0.07250.0014-0.0640.0263-0.0318-0.02750.112-0.02190.20020.0812-0.02480.26220.00060.1506-139.924746.8444105.6499
2100.0166-0.00530.01830.0252-0.0230.0464-0.0508-0.0965-0.0240.0479-0.09960.0647-0.01680.0762-0.09680.25190.0831-0.05310.3053-0.01040.1172-145.806248.5122116.843
211-0.0007-0.00070.00090.0018-0.00860.0053-0.0905-0.0113-0.00090.0708-0.074-0.0606-0.0427-0.0711-00.24050.0462-0.03640.17470.0090.1585-150.149543.4597104.374
2120.00760.008-0.00270.0088-0.00060.0049-0.028-0.0471-0.0561-0.0268-0.0249-0.0358-0.04180.0106-00.19890.0274-0.01530.19340.00940.1271-151.364150.5108100.2513
2130.0123-0.0050.00120.0365-0.00830.00670.054-0.00110.0145-0.11450.0250.0135-0.08470.08060.0170.19870.0303-0.04550.1496-0.03760.1248-143.464354.1299102.5865
2140.00110.00070.0020.0008-0.00180.0026-0.0833-0.00330.01060.0325-0.07540.04420.01140.0277-00.1648-0.0092-0.04810.21110.00960.3436-161.691945.275388.7028
Refinement TLS group
IDRefine-IDRefine TLS-IDSelection details
1X-RAY DIFFRACTION1CHAIN A AND (RESSEQ 1:37)
2X-RAY DIFFRACTION2CHAIN A AND (RESSEQ 38:50)
3X-RAY DIFFRACTION3CHAIN A AND (RESSEQ 51:84)
4X-RAY DIFFRACTION4CHAIN A AND (RESSEQ 85:94)
5X-RAY DIFFRACTION5CHAIN B AND (RESSEQ 1:16)
6X-RAY DIFFRACTION6CHAIN B AND (RESSEQ 17:44)
7X-RAY DIFFRACTION7CHAIN B AND (RESSEQ 45:51)
8X-RAY DIFFRACTION8CHAIN B AND (RESSEQ 52:84)
9X-RAY DIFFRACTION9CHAIN B AND (RESSEQ 85:94)
10X-RAY DIFFRACTION10CHAIN C AND (RESSEQ 1:16)
11X-RAY DIFFRACTION11CHAIN C AND (RESSEQ 17:37)
12X-RAY DIFFRACTION12CHAIN C AND (RESSEQ 38:60)
13X-RAY DIFFRACTION13CHAIN C AND (RESSEQ 61:73)
14X-RAY DIFFRACTION14CHAIN C AND (RESSEQ 74:94)
15X-RAY DIFFRACTION15CHAIN D AND (RESSEQ 1:16)
16X-RAY DIFFRACTION16CHAIN D AND (RESSEQ 17:37)
17X-RAY DIFFRACTION17CHAIN D AND (RESSEQ 38:60)
18X-RAY DIFFRACTION18CHAIN D AND (RESSEQ 61:73)
19X-RAY DIFFRACTION19CHAIN D AND (RESSEQ 74:84)
20X-RAY DIFFRACTION20CHAIN D AND (RESSEQ 85:94)
21X-RAY DIFFRACTION21CHAIN E AND (RESSEQ 1:9)
22X-RAY DIFFRACTION22CHAIN E AND (RESSEQ 10:16)
23X-RAY DIFFRACTION23CHAIN E AND (RESSEQ 17:37)
24X-RAY DIFFRACTION24CHAIN E AND (RESSEQ 38:50)
25X-RAY DIFFRACTION25CHAIN E AND (RESSEQ 51:84)
26X-RAY DIFFRACTION26CHAIN E AND (RESSEQ 85:94)
27X-RAY DIFFRACTION27CHAIN F AND (RESSEQ 1:37)
28X-RAY DIFFRACTION28CHAIN F AND (RESSEQ 38:84)
29X-RAY DIFFRACTION29CHAIN F AND (RESSEQ 85:94)
30X-RAY DIFFRACTION30CHAIN G AND (RESSEQ 1:16)
31X-RAY DIFFRACTION31CHAIN G AND (RESSEQ 17:37)
32X-RAY DIFFRACTION32CHAIN G AND (RESSEQ 38:60)
33X-RAY DIFFRACTION33CHAIN G AND (RESSEQ 61:73)
34X-RAY DIFFRACTION34CHAIN G AND (RESSEQ 74:94)
35X-RAY DIFFRACTION35CHAIN H AND (RESSEQ 1:9)
36X-RAY DIFFRACTION36CHAIN H AND (RESSEQ 10:37)
37X-RAY DIFFRACTION37CHAIN H AND (RESSEQ 38:51)
38X-RAY DIFFRACTION38CHAIN H AND (RESSEQ 52:84)
39X-RAY DIFFRACTION39CHAIN H AND (RESSEQ 85:94)
40X-RAY DIFFRACTION40CHAIN I AND (RESSEQ 1:9)
41X-RAY DIFFRACTION41CHAIN I AND (RESSEQ 10:16)
42X-RAY DIFFRACTION42CHAIN I AND (RESSEQ 17:37)
43X-RAY DIFFRACTION43CHAIN I AND (RESSEQ 38:60)
44X-RAY DIFFRACTION44CHAIN I AND (RESSEQ 61:84)
45X-RAY DIFFRACTION45CHAIN I AND (RESSEQ 85:94)
46X-RAY DIFFRACTION46CHAIN J AND (RESSEQ 1:16)
47X-RAY DIFFRACTION47CHAIN J AND (RESSEQ 17:50)
48X-RAY DIFFRACTION48CHAIN J AND (RESSEQ 51:84)
49X-RAY DIFFRACTION49CHAIN J AND (RESSEQ 85:94)
50X-RAY DIFFRACTION50CHAIN K AND (RESSEQ 1:16)
51X-RAY DIFFRACTION51CHAIN K AND (RESSEQ 17:37)
52X-RAY DIFFRACTION52CHAIN K AND (RESSEQ 38:60)
53X-RAY DIFFRACTION53CHAIN K AND (RESSEQ 61:84)
54X-RAY DIFFRACTION54CHAIN K AND (RESSEQ 85:94)
55X-RAY DIFFRACTION55CHAIN L AND (RESSEQ 1:9)
56X-RAY DIFFRACTION56CHAIN L AND (RESSEQ 10:16)
57X-RAY DIFFRACTION57CHAIN L AND (RESSEQ 17:37)
58X-RAY DIFFRACTION58CHAIN L AND (RESSEQ 38:60)
59X-RAY DIFFRACTION59CHAIN L AND (RESSEQ 61:73)
60X-RAY DIFFRACTION60CHAIN L AND (RESSEQ 74:84)
61X-RAY DIFFRACTION61CHAIN L AND (RESSEQ 85:94)
62X-RAY DIFFRACTION62CHAIN M AND (RESSEQ 1:9)
63X-RAY DIFFRACTION63CHAIN M AND (RESSEQ 10:16)
64X-RAY DIFFRACTION64CHAIN M AND (RESSEQ 17:36)
65X-RAY DIFFRACTION65CHAIN M AND (RESSEQ 37:50)
66X-RAY DIFFRACTION66CHAIN M AND (RESSEQ 51:84)
67X-RAY DIFFRACTION67CHAIN M AND (RESSEQ 85:94)
68X-RAY DIFFRACTION68CHAIN N AND (RESSEQ 1:16)
69X-RAY DIFFRACTION69CHAIN N AND (RESSEQ 17:37)
70X-RAY DIFFRACTION70CHAIN N AND (RESSEQ 38:50)
71X-RAY DIFFRACTION71CHAIN N AND (RESSEQ 51:60)
72X-RAY DIFFRACTION72CHAIN N AND (RESSEQ 61:73)
73X-RAY DIFFRACTION73CHAIN N AND (RESSEQ 74:94)
74X-RAY DIFFRACTION74CHAIN O AND (RESSEQ 1:16)
75X-RAY DIFFRACTION75CHAIN O AND (RESSEQ 17:37)
76X-RAY DIFFRACTION76CHAIN O AND (RESSEQ 38:60)
77X-RAY DIFFRACTION77CHAIN O AND (RESSEQ 61:70)
78X-RAY DIFFRACTION78CHAIN O AND (RESSEQ 71:83)
79X-RAY DIFFRACTION79CHAIN O AND (RESSEQ 84:94)
80X-RAY DIFFRACTION80CHAIN P AND (RESSEQ 1:9)
81X-RAY DIFFRACTION81CHAIN P AND (RESSEQ 10:16)
82X-RAY DIFFRACTION82CHAIN P AND (RESSEQ 17:37)
83X-RAY DIFFRACTION83CHAIN P AND (RESSEQ 38:44)
84X-RAY DIFFRACTION84CHAIN P AND (RESSEQ 45:50)
85X-RAY DIFFRACTION85CHAIN P AND (RESSEQ 51:60)
86X-RAY DIFFRACTION86CHAIN P AND (RESSEQ 61:84)
87X-RAY DIFFRACTION87CHAIN P AND (RESSEQ 85:94)
88X-RAY DIFFRACTION88CHAIN R AND (RESSEQ 1:16)
89X-RAY DIFFRACTION89CHAIN R AND (RESSEQ 17:36)
90X-RAY DIFFRACTION90CHAIN R AND (RESSEQ 37:60)
91X-RAY DIFFRACTION91CHAIN R AND (RESSEQ 61:71)
92X-RAY DIFFRACTION92CHAIN R AND (RESSEQ 72:84)
93X-RAY DIFFRACTION93CHAIN R AND (RESSEQ 85:94)
94X-RAY DIFFRACTION94CHAIN S AND (RESSEQ 1:16)
95X-RAY DIFFRACTION95CHAIN S AND (RESSEQ 17:36)
96X-RAY DIFFRACTION96CHAIN S AND (RESSEQ 37:60)
97X-RAY DIFFRACTION97CHAIN S AND (RESSEQ 61:73)
98X-RAY DIFFRACTION98CHAIN S AND (RESSEQ 74:94)
99X-RAY DIFFRACTION99CHAIN T AND (RESSEQ 1:9)
100X-RAY DIFFRACTION100CHAIN T AND (RESSEQ 10:16)
101X-RAY DIFFRACTION101CHAIN T AND (RESSEQ 17:37)
102X-RAY DIFFRACTION102CHAIN T AND (RESSEQ 38:50)
103X-RAY DIFFRACTION103CHAIN T AND (RESSEQ 51:60)
104X-RAY DIFFRACTION104CHAIN T AND (RESSEQ 61:73)
105X-RAY DIFFRACTION105CHAIN T AND (RESSEQ 74:94)
106X-RAY DIFFRACTION106CHAIN U AND (RESSEQ 1:9)
107X-RAY DIFFRACTION107CHAIN U AND (RESSEQ 10:16)
108X-RAY DIFFRACTION108CHAIN U AND (RESSEQ 17:37)
109X-RAY DIFFRACTION109CHAIN U AND (RESSEQ 38:51)
110X-RAY DIFFRACTION110CHAIN U AND (RESSEQ 52:84)
111X-RAY DIFFRACTION111CHAIN U AND (RESSEQ 85:94)
112X-RAY DIFFRACTION112CHAIN V AND (RESSEQ 1:45)
113X-RAY DIFFRACTION113CHAIN V AND (RESSEQ 46:60)
114X-RAY DIFFRACTION114CHAIN V AND (RESSEQ 61:84)
115X-RAY DIFFRACTION115CHAIN V AND (RESSEQ 85:94)
116X-RAY DIFFRACTION116CHAIN W AND (RESSEQ 1:16)
117X-RAY DIFFRACTION117CHAIN W AND (RESSEQ 17:37)
118X-RAY DIFFRACTION118CHAIN W AND (RESSEQ 38:60)
119X-RAY DIFFRACTION119CHAIN W AND (RESSEQ 61:73)
120X-RAY DIFFRACTION120CHAIN W AND (RESSEQ 74:84)
121X-RAY DIFFRACTION121CHAIN W AND (RESSEQ 85:94)
122X-RAY DIFFRACTION122CHAIN X AND (RESSEQ 1:37)
123X-RAY DIFFRACTION123CHAIN X AND (RESSEQ 38:50)
124X-RAY DIFFRACTION124CHAIN X AND (RESSEQ 51:84)
125X-RAY DIFFRACTION125CHAIN X AND (RESSEQ 85:94)
126X-RAY DIFFRACTION126CHAIN Y AND (RESSEQ 1:36)
127X-RAY DIFFRACTION127CHAIN Y AND (RESSEQ 37:50)
128X-RAY DIFFRACTION128CHAIN Y AND (RESSEQ 51:73)
129X-RAY DIFFRACTION129CHAIN Y AND (RESSEQ 74:91)
130X-RAY DIFFRACTION130CHAIN Z AND (RESSEQ 1:16)
131X-RAY DIFFRACTION131CHAIN Z AND (RESSEQ 17:45)
132X-RAY DIFFRACTION132CHAIN Z AND (RESSEQ 46:50)
133X-RAY DIFFRACTION133CHAIN Z AND (RESSEQ 51:73)
134X-RAY DIFFRACTION134CHAIN Z AND (RESSEQ 74:84)
135X-RAY DIFFRACTION135CHAIN Z AND (RESSEQ 85:94)
136X-RAY DIFFRACTION136CHAIN 1 AND (RESSEQ 1:37)
137X-RAY DIFFRACTION137CHAIN 1 AND (RESSEQ 38:50)
138X-RAY DIFFRACTION138CHAIN 1 AND (RESSEQ 51:84)
139X-RAY DIFFRACTION139CHAIN 1 AND (RESSEQ 85:94)
140X-RAY DIFFRACTION140CHAIN 2 AND (RESSEQ 1:9)
141X-RAY DIFFRACTION141CHAIN 2 AND (RESSEQ 10:16)
142X-RAY DIFFRACTION142CHAIN 2 AND (RESSEQ 17:37)
143X-RAY DIFFRACTION143CHAIN 2 AND (RESSEQ 38:51)
144X-RAY DIFFRACTION144CHAIN 2 AND (RESSEQ 52:84)
145X-RAY DIFFRACTION145CHAIN 2 AND (RESSEQ 85:94)
146X-RAY DIFFRACTION146CHAIN 3 AND (RESSEQ 1:9)
147X-RAY DIFFRACTION147CHAIN 3 AND (RESSEQ 10:18)
148X-RAY DIFFRACTION148CHAIN 3 AND (RESSEQ 19:36)
149X-RAY DIFFRACTION149CHAIN 3 AND (RESSEQ 37:50)
150X-RAY DIFFRACTION150CHAIN 3 AND (RESSEQ 51:84)
151X-RAY DIFFRACTION151CHAIN 3 AND (RESSEQ 85:94)
152X-RAY DIFFRACTION152CHAIN 4 AND (RESSEQ 1:16)
153X-RAY DIFFRACTION153CHAIN 4 AND (RESSEQ 17:36)
154X-RAY DIFFRACTION154CHAIN 4 AND (RESSEQ 37:44)
155X-RAY DIFFRACTION155CHAIN 4 AND (RESSEQ 45:50)
156X-RAY DIFFRACTION156CHAIN 4 AND (RESSEQ 51:60)
157X-RAY DIFFRACTION157CHAIN 4 AND (RESSEQ 61:71)
158X-RAY DIFFRACTION158CHAIN 4 AND (RESSEQ 72:84)
159X-RAY DIFFRACTION159CHAIN 4 AND (RESSEQ 85:94)
160X-RAY DIFFRACTION160CHAIN 5 AND (RESSEQ 1:16)
161X-RAY DIFFRACTION161CHAIN 5 AND (RESSEQ 17:37)
162X-RAY DIFFRACTION162CHAIN 5 AND (RESSEQ 38:50)
163X-RAY DIFFRACTION163CHAIN 5 AND (RESSEQ 51:84)
164X-RAY DIFFRACTION164CHAIN 5 AND (RESSEQ 85:92)
165X-RAY DIFFRACTION165CHAIN 6 AND (RESSEQ 1:16)
166X-RAY DIFFRACTION166CHAIN 6 AND (RESSEQ 17:37)
167X-RAY DIFFRACTION167CHAIN 6 AND (RESSEQ 38:45)
168X-RAY DIFFRACTION168CHAIN 6 AND (RESSEQ 46:50)
169X-RAY DIFFRACTION169CHAIN 6 AND (RESSEQ 51:84)
170X-RAY DIFFRACTION170CHAIN 6 AND (RESSEQ 85:94)
171X-RAY DIFFRACTION171CHAIN 7 AND (RESSEQ 1:9)
172X-RAY DIFFRACTION172CHAIN 7 AND (RESSEQ 10:16)
173X-RAY DIFFRACTION173CHAIN 7 AND (RESSEQ 17:37)
174X-RAY DIFFRACTION174CHAIN 7 AND (RESSEQ 38:44)
175X-RAY DIFFRACTION175CHAIN 7 AND (RESSEQ 45:51)
176X-RAY DIFFRACTION176CHAIN 7 AND (RESSEQ 52:84)
177X-RAY DIFFRACTION177CHAIN 7 AND (RESSEQ 85:92)
178X-RAY DIFFRACTION178CHAIN 8 AND (RESSEQ 1:17)
179X-RAY DIFFRACTION179CHAIN 8 AND (RESSEQ 18:36)
180X-RAY DIFFRACTION180CHAIN 8 AND (RESSEQ 37:50)
181X-RAY DIFFRACTION181CHAIN 8 AND (RESSEQ 51:73)
182X-RAY DIFFRACTION182CHAIN 8 AND (RESSEQ 74:94)
183X-RAY DIFFRACTION183CHAIN 9 AND (RESSEQ 1:16)
184X-RAY DIFFRACTION184CHAIN 9 AND (RESSEQ 17:44)
185X-RAY DIFFRACTION185CHAIN 9 AND (RESSEQ 45:51)
186X-RAY DIFFRACTION186CHAIN 9 AND (RESSEQ 52:84)
187X-RAY DIFFRACTION187CHAIN 9 AND (RESSEQ 85:94)
188X-RAY DIFFRACTION188CHAIN a AND (RESSEQ 1:36)
189X-RAY DIFFRACTION189CHAIN a AND (RESSEQ 37:51)
190X-RAY DIFFRACTION190CHAIN a AND (RESSEQ 52:84)
191X-RAY DIFFRACTION191CHAIN a AND (RESSEQ 85:94)
192X-RAY DIFFRACTION192CHAIN B AND (RESSEQ 1:16)
193X-RAY DIFFRACTION193CHAIN b AND (RESSEQ 17:37)
194X-RAY DIFFRACTION194CHAIN b AND (RESSEQ 38:50)
195X-RAY DIFFRACTION195CHAIN b AND (RESSEQ 51:73)
196X-RAY DIFFRACTION196CHAIN b AND (RESSEQ 74:94)
197X-RAY DIFFRACTION197CHAIN c AND (RESSEQ 1:37)
198X-RAY DIFFRACTION198CHAIN c AND (RESSEQ 38:50)
199X-RAY DIFFRACTION199CHAIN C AND (RESSEQ 51:84)
200X-RAY DIFFRACTION200CHAIN c AND (RESSEQ 85:94)
201X-RAY DIFFRACTION201CHAIN d AND (RESSEQ 1:37)
202X-RAY DIFFRACTION202CHAIN d AND (RESSEQ 38:50)
203X-RAY DIFFRACTION203CHAIN d AND (RESSEQ 51:84)
204X-RAY DIFFRACTION204CHAIN d AND (RESSEQ 85:94)
205X-RAY DIFFRACTION205CHAIN e AND (RESSEQ 1:37)
206X-RAY DIFFRACTION206CHAIN e AND (RESSEQ 38:50)
207X-RAY DIFFRACTION207CHAIN e AND (RESSEQ 51:84)
208X-RAY DIFFRACTION208CHAIN e AND (RESSEQ 85:94)
209X-RAY DIFFRACTION209CHAIN f AND (RESSEQ 1:16)
210X-RAY DIFFRACTION210CHAIN f AND (RESSEQ 17:36)
211X-RAY DIFFRACTION211CHAIN f AND (RESSEQ 37:50)
212X-RAY DIFFRACTION212CHAIN f AND (RESSEQ 51:60)
213X-RAY DIFFRACTION213CHAIN f AND (RESSEQ 61:84)
214X-RAY DIFFRACTION214CHAIN f AND (RESSEQ 85:94)

+
About Yorodumi

-
News

-
Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

Related info.:EMDB header

External links:wwPDB to switch to version 3 of the EMDB data model

-
Aug 12, 2020. Covid-19 info

Covid-19 info

URL: https://pdbjlvh1.pdbj.org/emnavi/covid19.php

New page: Covid-19 featured information page in EM Navigator.

Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

+
Mar 5, 2020. Novel coronavirus structure data

Novel coronavirus structure data

Related info.:Yorodumi Speices / Aug 12, 2020. Covid-19 info

External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

+
Jan 31, 2019. EMDB accession codes are about to change! (news from PDBe EMDB page)

EMDB accession codes are about to change! (news from PDBe EMDB page)

  • The allocation of 4 digits for EMDB accession codes will soon come to an end. Whilst these codes will remain in use, new EMDB accession codes will include an additional digit and will expand incrementally as the available range of codes is exhausted. The current 4-digit format prefixed with “EMD-” (i.e. EMD-XXXX) will advance to a 5-digit format (i.e. EMD-XXXXX), and so on. It is currently estimated that the 4-digit codes will be depleted around Spring 2019, at which point the 5-digit format will come into force.
  • The EM Navigator/Yorodumi systems omit the EMD- prefix.

Related info.:Q: What is EMD? / ID/Accession-code notation in Yorodumi/EM Navigator

External links:EMDB Accession Codes are Changing Soon! / Contact to PDBj

+
Jul 12, 2017. Major update of PDB

Major update of PDB

  • wwPDB released updated PDB data conforming to the new PDBx/mmCIF dictionary.
  • This is a major update changing the version number from 4 to 5, and with Remediation, in which all the entries are updated.
  • In this update, many items about electron microscopy experimental information are reorganized (e.g. em_software).
  • Now, EM Navigator and Yorodumi are based on the updated data.

External links:wwPDB Remediation / Enriched Model Files Conforming to OneDep Data Standards Now Available in the PDB FTP Archive

-
Yorodumi

Thousand views of thousand structures

  • Yorodumi is a browser for structure data from EMDB, PDB, SASBDB, etc.
  • This page is also the successor to EM Navigator detail page, and also detail information page/front-end page for Omokage search.
  • The word "yorodu" (or yorozu) is an old Japanese word meaning "ten thousand". "mi" (miru) is to see.

Related info.:EMDB / PDB / SASBDB / Comparison of 3 databanks / Yorodumi Search / Aug 31, 2016. New EM Navigator & Yorodumi / Yorodumi Papers / Jmol/JSmol / Function and homology information / Changes in new EM Navigator and Yorodumi

Read more