登録情報 | データベース: PDB / ID: 3pmb |
---|
タイトル | 2.9 Angstrom crystal structure of bovine thrombin in tetragonal spacegroup |
---|
要素 | - Thrombin heavy chain
- Thrombin light chain
|
---|
キーワード | HYDROLASE / Protease / Thrombosis / Fibrinolosys |
---|
機能・相同性 | 機能・相同性情報
fibrinogen binding / thrombin / protein polymerization / positive regulation of blood coagulation / acute-phase response / platelet activation / collagen-containing extracellular matrix / serine-type endopeptidase activity / calcium ion binding / proteolysis / extracellular space類似検索 - 分子機能 Prothrombin/thrombin / Thrombin light chain / Thrombin light chain domain superfamily / Thrombin light chain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. / Kringle domain profile. ...Prothrombin/thrombin / Thrombin light chain / Thrombin light chain domain superfamily / Thrombin light chain / Kringle domain / Kringle / Kringle, conserved site / Kringle superfamily / Kringle domain signature. / Kringle domain profile. / Kringle domain / Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain / Gamma-carboxyglutamic acid-rich (GLA) domain / Gamma-carboxyglutamic acid-rich (GLA) domain superfamily / Vitamin K-dependent carboxylation domain. / Gla domain profile. / Domain containing Gla (gamma-carboxyglutamate) residues. / Kringle-like fold / Serine proteases, trypsin family, histidine active site / Serine proteases, trypsin family, serine active site / Peptidase S1A, chymotrypsin family / Serine proteases, trypsin family, histidine active site. / Serine proteases, trypsin domain profile. / Serine proteases, trypsin family, serine active site. / Trypsin-like serine protease / Serine proteases, trypsin domain / Trypsin / Trypsin-like serine proteases / Thrombin, subunit H / Peptidase S1, PA clan, chymotrypsin-like fold / Peptidase S1, PA clan / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 |
---|
生物種 | Bos taurus (ウシ) |
---|
手法 | X線回折 / 分子置換 / 解像度: 2.9 Å |
---|
データ登録者 | Wright, H.T. / Scarsdale, J.N. / Desai, B.J. |
---|
引用 | ジャーナル: Biochemistry / 年: 2011 タイトル: Interaction of thrombin with sucrose octasulfate. 著者: Desai, B.J. / Boothello, R.S. / Mehta, A.Y. / Scarsdale, J.N. / Wright, H.T. / Desai, U.R. |
---|
履歴 | 登録 | 2010年11月16日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2011年7月20日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2011年8月24日 | Group: Database references |
---|
|
---|