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- PDB-3p6y: CF Im25-CF Im68-UGUAA complex -

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Basic information

Entry
Database: PDB / ID: 3p6y
TitleCF Im25-CF Im68-UGUAA complex
Components
  • 5'-R(*UP*GP*UP*AP*A)-3'
  • Cleavage and polyadenylation specificity factor subunit 5
  • Cleavage and polyadenylation specificity factor subunit 6
KeywordsRNA BINDING PROTEIN/RNA / RRM domain / RNA binding / nuclear / RNA BINDING PROTEIN-RNA complex
Function / homology
Function and homology information


exon-exon junction complex binding / positive regulation of pro-B cell differentiation / positive regulation of RNA export from nucleus / mRNA cleavage factor complex / co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway / interchromatin granule / Processing of Intronless Pre-mRNAs / positive regulation of stem cell differentiation / mRNA cleavage and polyadenylation specificity factor complex / perichromatin fibrils ...exon-exon junction complex binding / positive regulation of pro-B cell differentiation / positive regulation of RNA export from nucleus / mRNA cleavage factor complex / co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway / interchromatin granule / Processing of Intronless Pre-mRNAs / positive regulation of stem cell differentiation / mRNA cleavage and polyadenylation specificity factor complex / perichromatin fibrils / mRNA alternative polyadenylation / paraspeckles / mRNA 3'-UTR AU-rich region binding / mRNA 3'-end processing / Signaling by cytosolic FGFR1 fusion mutants / mRNA 3'-end processing / RNA Polymerase II Transcription Termination / protein heterotetramerization / post-transcriptional regulation of gene expression / ribosomal large subunit binding / Processing of Capped Intron-Containing Pre-mRNA / centriolar satellite / Signaling by FGFR1 in disease / protein tetramerization / histone deacetylase binding / mRNA processing / cell differentiation / nuclear body / nuclear speck / ribonucleoprotein complex / mRNA binding / centrosome / chromatin binding / protein homodimerization activity / RNA binding / nucleoplasm / identical protein binding / membrane / nucleus / cytoplasm
Similarity search - Function
Cleavage and polyadenylation specificity factor subunit 6 / CPSF6/7 family / Cleavage/polyadenylation specificity factor subunit 5 / Nucleotide hydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nudix hydrolase domain profile. / RRM (RNA recognition motif) domain / NUDIX hydrolase domain / NUDIX hydrolase-like domain superfamily ...Cleavage and polyadenylation specificity factor subunit 6 / CPSF6/7 family / Cleavage/polyadenylation specificity factor subunit 5 / Nucleotide hydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nudix hydrolase domain profile. / RRM (RNA recognition motif) domain / NUDIX hydrolase domain / NUDIX hydrolase-like domain superfamily / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / Alpha-Beta Complex / 2-Layer Sandwich / Alpha Beta
Similarity search - Domain/homology
RNA / Cleavage and polyadenylation specificity factor subunit 5 / Cleavage and polyadenylation specificity factor subunit 6
Similarity search - Component
Biological speciesHomo sapiens (human)
MethodX-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.9 Å
AuthorsLi, H. / Tong, S. / Li, X. / Shi, H. / Gao, Y. / Ge, H. / Niu, L. / Teng, M.
CitationJournal: To be Published
Title: Structural basis of pre-mRNA recognition by the human cleavage factor Im complex
Authors: Li, H. / Tong, S. / Li, X. / Shi, H. / Gao, Y. / Ge, H. / Niu, L. / Teng, M.
History
DepositionOct 11, 2010Deposition site: RCSB / Processing site: PDBJ
Revision 1.0Nov 3, 2010Provider: repository / Type: Initial release
Revision 1.1Jul 13, 2011Group: Version format compliance
Revision 1.2Nov 1, 2023Group: Data collection / Database references / Refinement description
Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif
Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details

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Structure visualization

Structure viewerMolecule:
MolmilJmol/JSmol

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Assembly

Deposited unit
A: Cleavage and polyadenylation specificity factor subunit 5
B: Cleavage and polyadenylation specificity factor subunit 5
C: Cleavage and polyadenylation specificity factor subunit 6
D: Cleavage and polyadenylation specificity factor subunit 6
E: Cleavage and polyadenylation specificity factor subunit 5
F: Cleavage and polyadenylation specificity factor subunit 5
G: Cleavage and polyadenylation specificity factor subunit 6
H: Cleavage and polyadenylation specificity factor subunit 6
I: Cleavage and polyadenylation specificity factor subunit 5
J: Cleavage and polyadenylation specificity factor subunit 5
K: Cleavage and polyadenylation specificity factor subunit 6
L: Cleavage and polyadenylation specificity factor subunit 6
M: Cleavage and polyadenylation specificity factor subunit 5
N: Cleavage and polyadenylation specificity factor subunit 5
O: Cleavage and polyadenylation specificity factor subunit 6
P: Cleavage and polyadenylation specificity factor subunit 6
Q: 5'-R(*UP*GP*UP*AP*A)-3'
R: 5'-R(*UP*GP*UP*AP*A)-3'
S: 5'-R(*UP*GP*UP*AP*A)-3'
T: 5'-R(*UP*GP*UP*AP*A)-3'
U: 5'-R(*UP*GP*UP*AP*A)-3'
V: 5'-R(*UP*GP*UP*AP*A)-3'
W: 5'-R(*UP*GP*UP*AP*A)-3'


Theoretical massNumber of molelcules
Total (without water)281,10523
Polymers281,10523
Non-polymers00
Water1,24369
1
A: Cleavage and polyadenylation specificity factor subunit 5
B: Cleavage and polyadenylation specificity factor subunit 5
C: Cleavage and polyadenylation specificity factor subunit 6
D: Cleavage and polyadenylation specificity factor subunit 6
Q: 5'-R(*UP*GP*UP*AP*A)-3'
R: 5'-R(*UP*GP*UP*AP*A)-3'


Theoretical massNumber of molelcules
Total (without water)70,6696
Polymers70,6696
Non-polymers00
Water724
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
2
E: Cleavage and polyadenylation specificity factor subunit 5
F: Cleavage and polyadenylation specificity factor subunit 5
G: Cleavage and polyadenylation specificity factor subunit 6
H: Cleavage and polyadenylation specificity factor subunit 6
S: 5'-R(*UP*GP*UP*AP*A)-3'
W: 5'-R(*UP*GP*UP*AP*A)-3'


Theoretical massNumber of molelcules
Total (without water)70,6696
Polymers70,6696
Non-polymers00
Water724
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
3
I: Cleavage and polyadenylation specificity factor subunit 5
J: Cleavage and polyadenylation specificity factor subunit 5
K: Cleavage and polyadenylation specificity factor subunit 6
L: Cleavage and polyadenylation specificity factor subunit 6
T: 5'-R(*UP*GP*UP*AP*A)-3'


Theoretical massNumber of molelcules
Total (without water)69,0985
Polymers69,0985
Non-polymers00
Water724
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
4
M: Cleavage and polyadenylation specificity factor subunit 5
N: Cleavage and polyadenylation specificity factor subunit 5
O: Cleavage and polyadenylation specificity factor subunit 6
P: Cleavage and polyadenylation specificity factor subunit 6
U: 5'-R(*UP*GP*UP*AP*A)-3'
V: 5'-R(*UP*GP*UP*AP*A)-3'


Theoretical massNumber of molelcules
Total (without water)70,6696
Polymers70,6696
Non-polymers00
Water724
TypeNameSymmetry operationNumber
identity operation1_555x,y,z1
Unit cell
Length a, b, c (Å)104.783, 129.419, 111.159
Angle α, β, γ (deg.)90.00, 94.01, 90.00
Int Tables number4
Space group name H-MP1211

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Components

#1: Protein
Cleavage and polyadenylation specificity factor subunit 5 / Cleavage factor Im 25 / Cleavage and polyadenylation specificity factor 25 kDa subunit / CPSF 25 ...Cleavage factor Im 25 / Cleavage and polyadenylation specificity factor 25 kDa subunit / CPSF 25 kDa subunit / Nucleoside diphosphate-linked moiety X motif 21 / Nudix motif 21 / Pre-mRNA cleavage factor Im 25 kDa subunit


Mass: 23614.115 Da / Num. of mol.: 8 / Fragment: UNP residues 34-227
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: NUDT21, CFIM25, CPSF25, CPSF5 / Production host: Escherichia coli (E. coli) / References: UniProt: O43809
#2: Protein
Cleavage and polyadenylation specificity factor subunit 6 / Cleavage factor Im 68 / Cleavage and polyadenylation specificity factor 68 kDa subunit / CF Im68 / ...Cleavage factor Im 68 / Cleavage and polyadenylation specificity factor 68 kDa subunit / CF Im68 / CPSF 68 kDa subunit / Pre-mRNA cleavage factor Im 68 kDa subunit / Protein HPBRII-4/7


Mass: 10149.415 Da / Num. of mol.: 8 / Fragment: UNP residues 80-161 / Mutation: C159S
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: CPSF6, CFIM68 / Production host: Escherichia coli (E. coli) / References: UniProt: Q16630
#3: RNA chain
5'-R(*UP*GP*UP*AP*A)-3'


Mass: 1570.992 Da / Num. of mol.: 7 / Source method: obtained synthetically
#4: Water ChemComp-HOH / water


Mass: 18.015 Da / Num. of mol.: 69 / Source method: isolated from a natural source / Formula: H2O

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Experimental details

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Experiment

ExperimentMethod: X-RAY DIFFRACTION / Number of used crystals: 1

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Sample preparation

CrystalDensity Matthews: 2.67 Å3/Da / Density % sol: 54.01 %
Crystal growTemperature: 283 K / Method: vapor diffusion, sitting drop / pH: 5
Details: 15% PEG 3350, 9% dioxane and 0.1M sodium citrate, pH 5.0, VAPOR DIFFUSION, SITTING DROP, temperature 283K

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Data collection

DiffractionMean temperature: 100 K
Diffraction sourceSource: SYNCHROTRON / Site: SSRF / Beamline: BL17U
DetectorType: MARMOSAIC 225 mm CCD / Detector: CCD
RadiationMonochromator: GRAPHITE / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
Radiation wavelengthRelative weight: 1
ReflectionResolution: 2.9→50 Å / Num. all: 62810 / Num. obs: 59607 / % possible obs: 95.92 % / Observed criterion σ(F): 2 / Observed criterion σ(I): 2
Reflection shellResolution: 2.9→2.978 Å / % possible all: 95.92

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Processing

Software
NameVersionClassification
HKL-2000data collection
PHASESphasing
REFMAC5.5.0102refinement
HKL-2000data reduction
HKL-2000data scaling
RefinementMethod to determine structure: MOLECULAR REPLACEMENT
Starting model: 3P5T
Resolution: 2.9→50 Å / Cor.coef. Fo:Fc: 0.914 / Cor.coef. Fo:Fc free: 0.88 / SU B: 40.548 / SU ML: 0.353 / Cross valid method: THROUGHOUT / σ(F): 2 / ESU R Free: 0.448 / Stereochemistry target values: MAXIMUM LIKELIHOOD
RfactorNum. reflection% reflectionSelection details
Rfree0.27548 3182 5.1 %RANDOM
Rwork0.22632 ---
all0.239 62810 --
obs0.22877 59607 95.92 %-
Solvent computationIon probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.4 Å / Solvent model: MASK
Displacement parametersBiso mean: 61.269 Å2
Baniso -1Baniso -2Baniso -3
1--2.38 Å20 Å20.23 Å2
2---2.7 Å20 Å2
3---5.12 Å2
Refinement stepCycle: LAST / Resolution: 2.9→50 Å
ProteinNucleic acidLigandSolventTotal
Num. atoms17049 449 0 69 17567
Refine LS restraints
Refine-IDTypeDev idealDev ideal targetNumber
X-RAY DIFFRACTIONr_bond_refined_d0.0060.02218008
X-RAY DIFFRACTIONr_bond_other_d
X-RAY DIFFRACTIONr_angle_refined_deg1.0051.99224625
X-RAY DIFFRACTIONr_angle_other_deg
X-RAY DIFFRACTIONr_dihedral_angle_1_deg4.75252176
X-RAY DIFFRACTIONr_dihedral_angle_2_deg34.82123.866776
X-RAY DIFFRACTIONr_dihedral_angle_3_deg15.331152673
X-RAY DIFFRACTIONr_dihedral_angle_4_deg15.7541592
X-RAY DIFFRACTIONr_chiral_restr0.0660.22731
X-RAY DIFFRACTIONr_gen_planes_refined0.0040.02113757
X-RAY DIFFRACTIONr_gen_planes_other
X-RAY DIFFRACTIONr_nbd_refined
X-RAY DIFFRACTIONr_nbd_other
X-RAY DIFFRACTIONr_nbtor_refined
X-RAY DIFFRACTIONr_nbtor_other
X-RAY DIFFRACTIONr_xyhbond_nbd_refined
X-RAY DIFFRACTIONr_xyhbond_nbd_other
X-RAY DIFFRACTIONr_metal_ion_refined
X-RAY DIFFRACTIONr_metal_ion_other
X-RAY DIFFRACTIONr_symmetry_vdw_refined
X-RAY DIFFRACTIONr_symmetry_vdw_other
X-RAY DIFFRACTIONr_symmetry_hbond_refined
X-RAY DIFFRACTIONr_symmetry_hbond_other
X-RAY DIFFRACTIONr_symmetry_metal_ion_refined
X-RAY DIFFRACTIONr_symmetry_metal_ion_other
X-RAY DIFFRACTIONr_mcbond_it0.2611.510951
X-RAY DIFFRACTIONr_mcbond_other
X-RAY DIFFRACTIONr_mcangle_it0.484217535
X-RAY DIFFRACTIONr_scbond_it0.46437057
X-RAY DIFFRACTIONr_scangle_it0.8284.57090
X-RAY DIFFRACTIONr_rigid_bond_restr
X-RAY DIFFRACTIONr_sphericity_free
X-RAY DIFFRACTIONr_sphericity_bonded
LS refinement shellResolution: 2.903→2.978 Å / Total num. of bins used: 20
RfactorNum. reflection% reflection
Rfree0.359 176 -
Rwork0.305 3314 -
obs--72.42 %
Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

IDL112)L122)L132)L222)L232)L332)S11 (Å °)S12 (Å °)S13 (Å °)S21 (Å °)S22 (Å °)S23 (Å °)S31 (Å °)S32 (Å °)S33 (Å °)T112)T122)T132)T222)T232)T332)Origin x (Å)Origin y (Å)Origin z (Å)
17.3275-1.0578-0.99940.9042-0.45053.1818-0.0256-0.0544-0.2886-0.033-0.04990.2980.0942-0.24240.07560.39340.015-0.01050.2667-0.0280.326213.49412.0623-12.7649
25.2758-0.0898-0.96791.39890.93260.91480.5224-0.01580.44140.03860.0123-0.7922-0.30.0479-0.53470.4944-0.0132-0.05870.32970.03180.49626.540620.0456-20.6346
34.99422.402-2.07322.97630.47032.3093-0.04550.1036-0.06360.23730.1086-0.42040.10.2149-0.06310.4227-0.0877-0.02510.32570.02860.452919.739738.2019-8.075
43.56351.83881.53689.34410.84850.9365-0.20120.38190.47890.25550.17590.0862-0.345-0.01450.02530.41530.02330.13290.34140.05640.37629.878634.687-10.8562
55.1829-5.31620.28797.8415-2.85355.2592-0.0833-0.05160.0839-0.01080.0886-0.26620.23440.0293-0.00540.1934-0.0631-0.00360.2698-0.07660.306719.89646.0534-8.7757
610.88356.11151.28183.80610.50536.16190.0485-0.20910.74920.3011-0.0957-0.0054-0.76440.72740.04720.467-0.0179-0.17610.2747-0.02120.608129.16720.4418-8.6949
77.1268-3.18873.91835.0995-2.06622.6199-0.03850.14590.6841-0.2541-0.2294-0.0444-0.1546-0.0690.26780.34210.03180.05960.36630.00810.288412.751524.8885-14.3004
82.85827.6076-2.894822.0264-5.98655.4547-0.22940.0450.1011-0.6953-0.25740.4434-0.1289-0.48630.48680.2904-0.0042-0.06760.4198-0.0010.292710.676221.8861-19.8665
95.2254-2.2837-2.83548.84395.75415.9378-0.14030.51230.0429-0.8361-0.17450.0916-0.58960.26130.31480.312-0.0109-0.01510.38180.06230.328819.639516.4634-25.4689
102.6625-0.723-0.07351.05823.554917.93930.00540.6559-0.5083-0.1254-0.30020.11020.6788-0.56370.29480.5048-0.01330.0360.3504-0.0210.31959.595813.1712-16.355
110.13090.52380.29025.77721.69961.7493-0.04840.04410.11780.40210.084-0.0812-0.18720.1793-0.03560.25810.01120.00650.2590.02310.345112.616630.5317-0.5677
121.15140.7367-0.69351.65810.79472.64140.0590.18550.2891-0.1143-0.0081-0.1449-0.2283-0.1505-0.0510.1950.0145-0.00840.20870.04620.45449.35631.36172.9603
132.9967-1.7771-0.89171.36080.16221.62220.03490.2486-0.0326-0.1381-0.06740.04220.0844-0.06110.03260.269-0.0217-0.02560.28140.05510.220415.266814.6992-15.1851
142.36241.9575-2.83972.7551-3.44527.82270.1714-0.04970.10890.0672-0.2184-0.1384-0.3140.62050.0470.21780.03120.02910.21730.02860.245926.117213.2615-7.7226
154.05753.3088-0.60133.9487-0.2421.45730.0557-0.1912-0.1180.1147-0.107-0.1392-0.10620.05320.05140.24540.039-0.00250.2257-0.00640.192418.218314.67720.4999
164.805-6.3056-0.26748.8507-0.47713.7453-0.1823-0.0418-0.17580.11280.1271-0.21320.70880.04820.05520.3035-0.0276-0.05860.2309-0.01610.516412.8308-0.5854-8.6128
178.49090.344-0.64416.45510.86549.4648-0.21530.5868-0.2071-0.308-0.1832-0.13330.5504-0.12980.39860.1914-0.01610.01840.19840.03230.2425-6.696719.82934.0062
180.3797-1.0560.033410.0152-6.11096.1175-0.1988-0.2079-0.0211.15810.2455-0.3314-0.4132-0.1455-0.04670.29430.0429-0.02450.43710.06310.2915-10.685514.957721.2046
194.2676-0.6761-1.96690.2125-0.10842.8913-0.02470.59860.414-0.06260.0114-0.07450.2697-0.45540.01340.4690.0211-0.04140.45590.04050.42025.2288-0.934326.8235
205.25293.156-0.4062.0406-0.726810.12470.0844-0.1840.01830.12810.1187-0.04530.39350.0059-0.20310.38920.0957-0.0550.4920.00160.324212.1878-9.715518.6822
212.1577-4.22270.312412.5566-1.71630.7683-0.2462-0.1371-0.16570.53290.2738-0.13740.1390.1553-0.02750.2153-0.0288-0.02440.2921-0.00880.18761.73587.210610.9621
222.30950.7288-0.82983.2328-1.69265.9152-0.1503-0.25860.040.28780.1291-0.2289-0.0235-0.01640.02120.18570.0027-0.02010.2744-0.04470.19040.784820.038315.0157
231.43261.58560.74363.2561.91343.73730.3163-0.15350.01020.7727-0.0485-0.05420.2040.2418-0.26780.42190.02440.02810.32910.03450.24384.91397.303819.4905
243.9644-5.5042.79713.3327-3.40625.95450.06740.2555-0.5564-0.6215-0.08720.58480.5847-0.24030.01970.3114-0.08240.01060.35380.03530.3444-3.363-4.35988.1419
256.37480.5304-0.77081.29831.15951.673-0.042-0.2915-0.21440.16850.14440.0623-0.0593-0.0064-0.10240.37370.02870.06870.38970.08890.3231-10.91964.295817.1593
267.8217-0.2874-2.17130.3591-0.3421.35040.15270.3148-0.04120.00860.03760.2688-0.0138-0.3854-0.19030.2773-0.0420.02910.3235-0.04520.2937-3.29297.12476.2968
271.60650.4462-1.80052.8095-2.633.8003-0.0075-0.0968-0.17610.1756-0.0449-0.0143-0.07710.09340.05240.2325-0.021-0.01070.19450.0030.187417.13120.072111.2583
281.2163-0.742-0.58461.98250.36250.6284-0.1081-0.1767-0.3050.0980.03620.1160.1278-0.09810.07190.1929-0.0248-0.01510.19990.00860.177517.5521-3.5265.359
298.1978-6.2701-0.65845.17151.07991.4671-0.03050.12150.13480.0654-0.01810.034-0.0583-0.17670.04860.2333-0.05610.01040.28020.04830.2627-5.00810.9248.1951
303.86453.0615-3.08742.4887-2.48782.5670.2164-0.45-0.0520.2807-0.2689-0.0021-0.17790.20120.05260.31370.03590.00020.31120.00220.23651.272216.165418.8907
313.0476-0.96452.51443.02820.3174.5459-0.0868-0.09560.26180.25240.0232-0.2062-0.09520.45670.06350.2212-0.0117-0.00610.252-0.02980.235514.431416.152815.4693
323.6349-1.22751.74152.5125-1.53685.89060.0820.25810.0165-0.0674-0.06160.0180.14820.2724-0.02050.1952-0.01240.02180.1963-0.0220.21678.101715.22625.8712
334.0077-2.43370.60265.5523-0.1520.25350.0705-0.1120.4420.2364-0.0756-0.0883-0.0531-0.2090.00510.2185-0.010.00580.32320.03520.2168-6.616824.67564.4522
341.3219-1.86370.94323.6434-1.97971.1343-0.2117-0.2708-0.04320.4980.1869-0.054-0.2029-0.1220.02480.2431-0.028-0.03650.2468-0.0030.19833.7402-7.48774.5834
355.732-0.4148-5.132812.9734-2.48838.06190.1320.05060.0655-0.32140.18180.3239-0.0105-0.3586-0.31380.2421-0.0296-0.01230.2260.01150.249928.2444-16.03162.3971
360.05670.3284-0.17052.2636-1.17610.63520.0129-0.00980.07890.26930.21990.4342-0.0685-0.1584-0.23280.32250.01510.01990.2915-0.01740.336230.3469-17.49538.6071
3716.4607-12.29050.311711.12041.5723.9248-0.2964-0.805-0.0390.55720.4572-0.02740.8254-0.0838-0.16070.3290.01140.02990.28880.03280.257927.58182.288811.162
381.1639-2.57190.25826.6917-0.31480.3666-0.2306-0.11540.1020.4750.1554-0.1238-0.03750.00290.07520.29940.0209-0.02750.2544-0.01350.267331.7104-5.48189.0541
399.3254-2.331-9.04323.06080.328911.4547-0.35260.6903-0.1421-0.1862-0.0428-0.21170.6547-0.7450.39540.4461-0.07260.02420.3407-0.07560.345440.0665-22.77449.4145
409.38231.69210.08276.30692.50981.0769-0.01290.10510.1158-0.05330.0448-0.30630.03940.0876-0.03180.26550.03670.10970.29010.0970.466640.0943-15.5985-0.1627
415.11181.12861.29733.4766-0.33714.3859-0.17930.0015-0.08720.3662-0.1261-0.1015-0.190.18540.30550.27580.01450.01960.20680.01710.301439.4227-9.7093.104
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815.71313.8343-1.62235.0387-4.01514.884-0.08390.08610.22090.0412-0.0429-0.0629-0.25840.16640.12690.2598-0.00630.0260.2098-0.05840.272955.2209-2.627851.9544
822.51450.76680.79123.55522.02882.4675-0.16970.3612-0.0736-0.5761-0.00890.1058-0.0073-0.01970.17850.2661-0.03050.01230.22090.00350.221115.771-36.485747.8858
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918.5486-4.6864-17.206735.4838-4.672644.79020.3328-0.12650.47921.1171-0.26890.1444-1.59210.4581-0.0640.6047-0.179-0.10170.7484-0.14141.14248.405917.9650.0308
9213.00883.82079.68531.16812.9077.32250.3677-1.24710.0611-0.0417-0.258-0.11810.1062-0.6453-0.10970.8282-0.2832-0.02941.1286-0.00471.3245.954526.229451.7999
9315.717-16.0843-7.39231.236816.390310.15120.5224-0.72322.28671.418-1.53861.08190.3437-1.21021.01610.9853-0.23440.63630.5394-0.43531.472935.501612.666347.4153
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950.88816.3312.660160.122729.510521.5515-0.3108-0.33130.431-0.523-0.6571.2049-0.24520.66280.96790.61990.1789-0.21190.6042-0.13280.966736.965119.522145.7954
963.93291.5950.09830.65460.02180.10730.1043-0.84991.20420.0389-0.37950.391-0.26150.12660.27521.1424-0.3088-0.00010.94510.23141.601745.869628.043542.1423
973.81242.9701-2.32662.6859-0.06711.53380.14980.21380.3696-0.1226-0.00290.2456-1.7193-0.1019-0.14690.84770.16580.1680.5590.38891.127944.376219.642638.1971
984.330.21282.06173.2293-0.89072.8596-0.0008-0.17610.21920.2361-0.1833-0.2532-0.05150.13670.1840.3885-0.00980.06650.3621-0.02840.300615.96747.312372.9342
9910.504-0.3789-0.3771.7656-0.19682.69980.1117-0.39330.08270.1316-0.0586-0.202-0.0773-0.1048-0.05310.46650.019-0.00940.24170.06160.441715.445817.762966.9824
1002.70452.2981-0.812213.66463.1472.94450.19830.0287-0.39170.3155-0.1459-0.36930.201-0.1098-0.05250.3970.0248-0.07050.32150.00110.38236.633825.679468.0032
1011.87632.4182-0.40725.37971.22674.170.0673-0.01250.13380.0438-0.09220.2045-0.23150.0260.02490.25520.04290.01320.26260.02570.326516.460250.425564.1693
1027.93283.2651-2.16084.0486-1.58644.119-0.0329-0.0688-0.75130.1545-0.1316-0.15660.242-0.09040.16460.40480.04340.01740.27380.00220.316813.556832.92269.9151
1033.60415.10323.65457.67085.98166.20370.4916-0.1848-0.30980.4697-0.0262-0.65450.10830.2654-0.46540.5242-0.1110.06610.40250.09350.30110.700235.368777.6062
1042.87510.59821.14072.1225-1.73136.61080.1794-1.13830.1860.2373-0.15110.00870.0752-0.2576-0.02820.55440.0150.02170.54510.00910.426216.82542.304283.2083
1053.5973-2.1392-6.13198.17024.865311.04620.2054-0.26850.18140.3855-0.151-0.1465-0.18410.0353-0.05440.4138-0.1390.17960.6501-0.08250.37125.787143.842974.6263
1061.13161.95180.53313.40451.042.9385-0.0731-0.0227-0.0411-0.0874-0.06940.02440.0965-0.16010.14260.2279-0.00060.0350.250.0360.33289.001526.555858.1876
1071.1252-1.6383-0.24065.46672.22522.94970.07440.0425-0.00930.0396-0.0484-0.23650.21330.0354-0.0260.19030.00330.0350.20340.02590.28746.176826.250552.5179
1082.77390.57171.14366.4344.60483.87860.2849-0.5979-0.1204-0.125-0.3444-0.0402-0.0512-0.29810.05960.3315-0.04140.03330.27340.05340.28124.358724.060560.5761
1092.21822.14231.47746.06692.53122.06320.0052-0.59490.35110.0221-0.20240.1201-0.3663-0.06290.19720.3372-0.0030.05590.36150.00750.295110.797547.105473.1681
1100.89460.6370.03262.0183-1.70953.1648-0.0352-0.1966-0.19870.18350.0095-0.2420.19560.2060.02570.29410.0446-0.00010.29050.02510.291423.036941.794468.5741
1110.4613-1.4207-0.08054.9837-0.61813.4530.0218-0.003-0.0594-0.0499-0.2625-0.09490.1860.29270.24060.2433-0.018400.25980.03030.226218.31539.223354.7
1123.1017-0.3783.071.3665-0.29723.2015-0.086-0.25990.16970.049-0.01820.1658-0.2118-0.40960.10420.2410.01290.02510.2910.00440.25038.094245.317656.7057
1134.05985.87324.145612.68683.15276.6402-0.3522-0.14820.4105-0.1318-0.0240.0852-0.6494-0.15080.37620.31640.0462-0.05980.29680.01170.51938.472756.036863.8241
1146.5863-2.8918-0.04676.5754-0.40580.6222-0.194-1.37620.30340.06220.2076-0.3873-0.28770.2239-0.01350.4833-0.0211-0.00250.39320.00380.2271-9.246837.076456.812
1156.9183-6.9069-0.31667.9146-2.41499.64230.32110.46970.0091-0.7003-0.22160.140.6013-0.3358-0.09950.2754-0.0756-0.03740.31250.01540.3178-14.205732.821142.5851
11612.29357.844-6.01575.155-3.98874.2731-0.19580.41610.0233-0.08450.2522-0.2307-0.39210.1093-0.05640.47920.01720.00570.3872-0.1020.4812-6.564449.683629.219
1170.70980.2122-1.07318.56526.49719.1296-0.21130.4133-0.0256-0.7082-0.02130.1556-0.20970.17720.23260.4324-0.0448-0.00450.65160.08620.44438.787863.045534.8624
1186.99476.1223-1.27998.3532-5.41319.0037-0.19280.2039-0.001-0.14430.0373-0.3654-0.32450.36890.15560.26890.04120.00190.2748-0.00340.38671.729358.960544.3802
1192.45510.38121.00555.8971-1.13411.2387-0.00840.1968-0.0614-0.31250.08610.15890.11690.0348-0.07770.2251-0.01380.03010.2343-0.00060.2291-3.99834.987642.6639
1203.4869-4.5764-1.372112.64194.38584.4360.22490.11760.0798-0.5749-0.22340.0144-0.4522-0.0255-0.00150.2731-0.0303-0.00410.39070.03250.3455-1.444252.139740.3294
1216.4208-6.17597.786412.807-9.418710.3102-0.0779-0.37920.36020.1508-0.39530.1047-0.267-0.51740.47320.25120.0425-0.02620.4703-0.05190.3778-10.034354.669945.1867
12218.3344-1.8005-1.51430.43410.41440.4205-0.2678-0.0869-0.1375-0.04190.09510.1877-0.00910.04180.17280.36890.018-0.00620.2940.05230.3199-16.959348.092738.0699
1239.95150.1506-2.74340.08490.32583.0505-0.2435-1.01630.31660.0197-0.0780.15190.05-0.31010.32150.27170.0540.01410.3516-0.00330.387-8.546647.145951.087
1242.18492.0573-0.36543.3226-1.61551.40350.0427-0.1094-0.1985-0.023-0.2726-0.2414-0.11270.19820.22990.2244-0.0071-0.01140.2020.01730.295711.276155.413645.2144
1253.63140.6568-1.21630.3602-0.80612.149-0.1280.03410.1185-0.08210.06390.0411-0.0582-0.17890.06410.24510.0372-0.04940.1594-0.00410.23514.592756.256448.5838
1268.64915.70140.92336.3660.31621.59540.08290.0037-0.29840.0645-0.0764-0.13110.0569-0.1679-0.00640.22040.0512-0.00170.18920.01930.2437-6.116546.138948.0484
1270.60840.1319-0.0960.756-1.1632.8521-0.02630.22840.2687-0.1966-0.1113-0.08860.11640.07210.13750.30990.02220.0330.22790.02910.2965-1.333437.727838.1565
1281.7081-0.31631.29192.6085-2.3322.70660.04350.0586-0.07090.0132-0.0706-0.1454-0.00380.08460.02710.2210.0128-0.01570.1787-0.00990.27465.817139.724247.3455
1291.31141.98480.99096.47063.0947.20250.0911-0.4099-0.27040.0491-0.1684-0.0360.2249-0.44590.07740.1948-0.01870.02960.2850.10230.2568-10.621730.441152.4975
1301.53890.21790.18995.196-1.54930.855-0.25730.22680.1595-0.48880.2013-0.14520.1137-0.01530.05610.2768-0.03170.01480.24240.00020.234229.587762.4150.0699
1312.29310.1871.32011.67443.38638.3108-0.2335-0.18750.17260.1080.0419-0.0044-0.08790.0840.19170.31610.0334-0.01510.23240.01420.439925.222572.377751.3721
1320.0624-0.3759-0.0765.73520.38580.09550.12930.1122-0.0394-0.6299-0.18560.2803-0.164-0.13450.05630.44170.0813-0.02250.3898-0.01060.432626.278573.958243.6825
1338.28243.2266-3.517112.07992.46362.864-0.58470.82040.0802-1.00270.64220.0405-0.0497-0.1953-0.05750.318-0.0939-0.0520.36110.05460.299123.712654.176444.4701
1344.54124.506-0.76997.3956-0.62820.4571-0.20480.40550.2127-0.34370.2933-0.0254-0.0872-0.0642-0.08850.2891-0.0292-0.00260.29520.01420.302427.547760.284545.453
1350.7481.1165-1.42783.3903-4.78148.56950.073-0.00430.033-0.24440.2045-0.2317-0.27720.0085-0.27740.5116-0.10580.14540.33690.01110.55836.903876.188645.0306
1362.6214.03264.97426.54127.97910.0895-0.19290.11260.0664-0.4332-0.0541-0.1094-0.8139-0.00080.2470.4282-0.0577-0.16310.30020.11910.448734.770669.943555.8039
1370.87391.28832.7522.27324.756810.9380.07250.19390.0353-0.14840.25350.0118-0.25161.0381-0.3260.23080.01460.01580.2895-0.07310.29435.442964.727649.2
13815.2614-10.99478.467813.7025-9.3956.6147-0.272-0.23770.11320.3901-0.1485-0.7669-0.19690.14320.42050.3937-0.0219-0.00180.3518-0.05270.33937.6774.734445.3029
1395.41082.00461.457511.7282-5.35596.2099-0.0523-0.53080.15150.1986-0.05720.08360.0274-0.24840.10950.30790.00790.02670.2742-0.00660.3554-1.470917.560846.7054
1408.774510.0242-4.523819.91173.261611.1551-0.2851-0.2351-0.23980.61550.13580.21471.05660.4970.14930.63070.03460.07520.34220.0190.5347-4.15765.536350.8186
1414.76523.4091-0.799213.7524-6.45053.2430.5242-0.7385-0.01890.2633-0.56430.09640.0740.09690.04010.50360.00710.0530.3405-0.05840.40635.72078.168351.6163
1420.94781.2587-0.190815.8659-1.36380.55910.1685-0.06280.01770.3433-0.0762-0.3381-0.0179-0.0425-0.09220.3187-0.0027-0.00230.37650.01120.44258.681815.397846.1823
14317.1857-8.23151.41286.3659-1.24350.9512-0.37480.2254-0.8956-0.80780.58631.15920.0514-0.1908-0.21150.6102-0.1216-0.1410.46820.12710.7363.2471-4.593747.2237
1440.5465-0.1856-0.84170.85330.45441.4396-0.17760.5213-0.2357-0.0778-0.1370.12950.1815-0.78980.31450.5579-0.0708-0.15010.5919-0.10460.741-5.07115.226841.3795
1455.0154-1.0698-7.48931.50631.913411.422-0.0653-0.0775-0.1008-0.7793-0.17160.15820.19340.1040.23691.02530.1304-0.07840.4291-0.02460.53652.58766.114239.3842
1460.82830.5240.07584.50880.71811.2883-0.2328-0.4014-0.23130.3270.1786-0.2128-0.15110.08450.05410.52420.05890.00030.59270.03290.297471.811611.251716.8492
1470.3272-2.2059-3.165315.501422.134431.7433-0.0134-0.04410.0201-0.1236-0.17040.0684-0.31360.04380.18370.462-0.06570.02240.73660.18550.630178.9346-14.531912.9107
14812.5264-0.04680.06860.1808-0.6452.65240.1702-0.31940.16960.0561-0.0542-0.03360.11880.4395-0.1160.56430.09480.01540.4619-0.01810.636772.2761-19.67157.1402
14914.0235-2.65140.39220.5765-0.06970.1330.1406-0.9935-0.5866-0.00940.05470.23680.1674-0.1057-0.19530.50620.0405-0.00670.39590.0660.587263.836-23.124610.2162
1501.81221.146-0.14814.17640.39711.8918-0.07460.0271-0.1446-0.13590.12440.35650.0611-0.0636-0.04980.21880.05570.02150.44050.08910.325768.27183.76449.4198
1514.5777-2.04031.67364.7653-4.07775.48130.0761-0.1493-0.3952-0.26150.0214-0.23830.40980.0614-0.09740.2758-0.0091-0.00140.26510.02610.312776.69955.90188.5999
1527.21733.9014-3.07754.3782-1.59373.8721-0.16470.0071-0.85660.3504-0.11770.01220.3511-0.26070.28250.38270.00260.03790.39180.08320.431467.4215-5.547513.1217
15315.55887.62637.58564.51642.36547.404-0.0353-0.8210.5248-0.0963-0.501-0.11920.26640.26750.53630.43240.02020.07280.53840.10020.488769.1261-1.100921.379
1540.5628-0.2466-0.60142.71360.68471.0649-0.0839-0.25270.09310.6559-0.31190.09150.3721-0.1540.39580.4415-0.12240.26580.914-0.32170.742865.08395.173321.7764
1554.2593-2.3686-1.96681.48451.1414.1112-0.40720.1796-0.55380.3757-0.06080.48570.5779-0.02490.4680.3490.00270.01820.31890.06360.558862.6409-5.5731.6281
1565.7921-9.72263.723419.6096-9.44785.6817-0.1736-0.22480.0231-0.15120.1647-0.24470.4130.19340.00880.30980.01250.06720.3867-0.01940.513367.7712-13.099-2.197
1570.2658-0.90570.05384.96841.79642.49620.0208-0.0508-0.13850.22960.15580.02520.3075-0.0112-0.17660.2731-0.04820.01750.33690.0580.484360.301-10.68840.513
1580.0696-0.0311-0.1210.07860.20892.70640.0395-0.14420.0610.11390.0266-0.0783-0.129-0.1404-0.0660.3629-0.0589-0.03210.48460.05670.352672.16787.170719.2499
1591.2955-1.15682.65682.2195-4.26759.70620.14560.0524-0.1244-0.0693-0.3008-0.18870.44450.65560.15510.2203-0.0198-0.02070.23510.09860.322477.23296.96384.7419
1602.0144-0.53280.77943.5108-1.06131.48780.00720.1148-0.0564-0.1322-0.0043-0.09050.09830.0662-0.00280.2659-0.0283-0.02240.25820.02120.243170.57213.9124-0.9289
1610.47770.30410.77351.1162-1.01564.8243-0.1229-0.10640.16350.3233-0.0017-0.1187-0.83620.01820.12460.39040.0436-0.10460.3478-0.07510.405565.429219.19349.1017
1625.91790.39270.44323.92751.06918.4209-0.213-0.5624-0.2078-0.0064-0.0301-0.3389-1.0052-0.2360.2430.26620.0352-0.04760.23090.06520.327145.8062-1.2051-4.4482
1633.15094.0059-0.232515.9327-9.87099.2446-0.10650.435-0.0399-1.13850.34820.05390.6141-0.0272-0.24180.4010.04640.00010.4409-0.01780.28941.86113.8478-21.5307
16410.9279-1.5386-2.00440.5065-0.33121.80150.0286-0.19380.04680.0080.24930.20490.0464-0.5656-0.27790.4464-0.04990.06870.4409-0.0080.391457.081719.8301-26.9652
16518.3141-6.4516-2.089212.8495.27967.9958-0.37090.4492-0.5850.17720.6295-0.09910.5772-0.1062-0.25870.4311-0.0416-0.01690.2783-0.00690.228764.638924.6818-22.3881
16612.6845-6.64243.36096.4813-4.46695.456-0.15180.94850.3561-0.29580.064-0.1494-0.32430.23070.08780.5383-0.24320.02380.57940.08220.226165.226530.6813-16.9328
1671.14211.7882-0.30825.3214-1.1871.464-0.13480.1783-0.1006-0.29050.1618-0.13480.0462-0.1233-0.0270.20050.02640.02020.32060.00940.297753.89956.7362-12.6041
1683.2991-1.7173-2.27245.03431.21322.42820.06750.1739-0.07-0.4667-0.1093-0.0049-0.26460.01550.04180.3043-0.0116-0.02960.37660.03170.266254.820816.0187-15.9902
1694.67842.5293.959212.3634-4.83899.67960.1381-0.3360.1695-0.1991-0.32910.21790.1162-0.47680.1910.30530.0887-0.0370.3545-0.00060.238945.915917.9564-12.1617
17012.5851-3.0552-0.2531.09620.47651.128-0.32440.5130.08890.0213-0.01590.1783-0.15630.13060.34030.3824-0.02360.01150.34780.05680.271938.458512.5842-18.8603
1713.70842.6644-2.43062.3671-1.76871.8861-0.0212-0.115-0.1445-0.0233-0.14740.12350.0998-0.27840.16860.2715-0.00850.02270.5387-0.00850.380746.592210.7241-5.9936
1721.4069-0.26151.76973.1325-0.86262.3572-0.02150.0692-0.0643-0.16970.009-0.11280.01890.05340.01260.15310.00070.00030.17640.01270.189869.117617.8353-8.9536
1735.52472.72261.06241.96370.93720.6277-0.0077-0.097-0.0984-0.0492-0.05080.17870.0414-0.14590.05850.18330.04020.00510.21820.05610.203158.147715.6248-7.1271
1742.1746-1.4620.69091.9221-2.1243.26070.16990.69250.0085-0.1165-0.3554-0.1435-0.11790.08860.18550.3241-0.03920.01480.4168-0.04310.304149.54563.8612-20.217
1752.07782.4554-4.71483.6248-5.622311.6377-0.1480.0519-0.0908-0.14040.2172-0.14610.51450.407-0.06920.32550.10470.04610.4302-0.01850.38166.2164-0.7313-14.4339
1762.1221.9527-1.87822.9033-2.80786.48310.0799-0.0252-0.1778-0.0066-0.0551-0.169-0.10620.1868-0.02480.23910.0103-0.02440.2356-0.00640.282861.50283.7999-8.4631
1775.53193.6921-1.52525.5787-0.56180.5163-0.11290.3433-0.3796-0.14130.0389-0.24290.0825-0.11260.07390.23510.00330.00860.28580.01250.321245.589-6.305-5.4862
1781.0612.245-3.85965.1396-8.743114.9090.0520.15520.0906-0.21180.26270.15220.2888-0.4315-0.31470.2888-0.0328-0.00490.25160.03520.232290.070230.9258-12.3268
1791.37311.03730.25168.6447-0.88593.7546-0.0209-0.0689-0.0065-0.05720.13950.3995-0.0765-0.3652-0.11850.1743-0.0080.00720.22140.06520.234982.396724.213-0.2637
1809.01323.0727-0.47576.82070.64914.53070.14520.03350.08290.0779-0.09710.0831-0.44260.2936-0.04810.23050.00840.010.20490.00760.270283.263637.3356-2.2786
1810.0949-0.15110.15172.6471-1.28030.7652-0.0865-0.03960.0231-0.38160.30470.5718-0.0148-0.1337-0.21820.3857-0.0121-0.07490.23960.03610.311981.807430.281-10.6972
1823.04224.1634-1.05759.305-0.99830.7263-0.19790.28620.2007-0.4650.28680.2306-0.0114-0.0696-0.08890.2361-0.01640.01180.2722-0.010.228982.871822.3226-10.0417
1832.13961.10523.41377.2733-4.85412.1447-0.1262-0.147-0.0199-0.1467-0.0741-0.2982-0.1677-0.01530.20030.3567-0.03270.08370.3106-0.02460.362192.71140.7117-9.5502
1845.40221.9435-2.65892.00121.16245.02040.1271-0.30710.0155-0.1532-0.1572-0.12-0.42970.250.03010.27730.0307-0.01290.30680.0250.359691.900134.01890.8984
1855.58960.3213-4.39984.35681.01344.75230.01310.50870.086-0.470.1687-0.3395-0.1391-0.3381-0.18190.2457-0.0417-0.02480.31160.01340.295292.160828.3998-5.1998
1862.31211.38610.1515.2761.51590.6283-0.023-0.6980.2263-0.0110.1837-0.18280.07060.2723-0.16070.58250.06750.02730.5825-0.13270.721757.1832-21.2896-14.0975
18712.91098.1717-2.802120.9801-9.58834.6606-0.2723-1.1137-1.4058-0.77670.0428-0.71690.5477-0.20660.22940.8223-0.0124-0.09680.4592-0.02320.901951.6959-30.619-9.0829
1884.78278.73113.742529.7574-4.605413.51910.9197-0.80130.39850.7459-2.06990.70561.10420.22661.15020.8169-0.0692-0.01640.59260.00570.931461.6366-28.0474-7.7649
1895.2081-5.57181.24777.527-2.12820.72760.2210.3007-0.3619-0.332-0.18120.24780.19920.0177-0.03980.49380.0430.16660.5232-0.15190.625265.552-13.0804-13.4338
1900.8264-4.1019-1.172924.76737.11062.35540.015-0.2018-0.3729-1.16330.05330.6459-0.0829-0.0199-0.06830.87820.0247-0.14290.6840.06011.202663.4906-32.4336-10.8322
19151.006-2.49133.24952.98452.3122.34550.52063.0201-0.12090.655-0.2275-0.2460.66210.1222-0.29310.9872-0.1076-0.0640.6858-0.07041.140656.854-38.6562-15.8111
1921.0922.64630.05156.51160.12460.0531-0.26660.1826-0.4858-0.79530.2385-0.91480.13210.03760.02810.76230.1623-0.23290.8705-0.34951.12549.9858-27.4416-18.7099
1936.86425.3876-1.43867.18033.83288.6532-0.42560.5451-0.3297-0.5646-0.03880.0302-0.252-0.8550.46440.98650.0197-0.1150.6771-0.31451.097557.8782-28.6016-20.6754
1946.08582.1683.084215.9394-3.18162.77770.3945-0.3011-0.65490.78580.09840.49530.0388-0.1894-0.49290.64430.0782-0.05110.70220.06070.486111.2717.785427.7484
1955.4449-3.2211.24832.6941-1.30942.876-0.2457-0.30930.30840.71110.07970.24350.3735-1.04760.1661.0575-0.49910.16531.14670.16520.836115.9731-1.09162.0753
Refinement TLS group
IDRefine-IDRefine TLS-IDAuth asym-IDAuth seq-ID
1X-RAY DIFFRACTION1A34 - 44
2X-RAY DIFFRACTION2A45 - 57
3X-RAY DIFFRACTION3A58 - 71
4X-RAY DIFFRACTION4A72 - 80
5X-RAY DIFFRACTION5A81 - 95
6X-RAY DIFFRACTION6A96 - 103
7X-RAY DIFFRACTION7A104 - 118
8X-RAY DIFFRACTION8A119 - 124
9X-RAY DIFFRACTION9A125 - 135
10X-RAY DIFFRACTION10A136 - 146
11X-RAY DIFFRACTION11A147 - 154
12X-RAY DIFFRACTION12A155 - 169
13X-RAY DIFFRACTION13A170 - 188
14X-RAY DIFFRACTION14A189 - 202
15X-RAY DIFFRACTION15A203 - 221
16X-RAY DIFFRACTION16A222 - 228
17X-RAY DIFFRACTION17B34 - 42
18X-RAY DIFFRACTION18B43 - 51
19X-RAY DIFFRACTION19B52 - 62
20X-RAY DIFFRACTION20B63 - 74
21X-RAY DIFFRACTION21B75 - 88
22X-RAY DIFFRACTION22B89 - 99
23X-RAY DIFFRACTION23B100 - 111
24X-RAY DIFFRACTION24B112 - 121
25X-RAY DIFFRACTION25B122 - 135
26X-RAY DIFFRACTION26B136 - 148
27X-RAY DIFFRACTION27B149 - 159
28X-RAY DIFFRACTION28B160 - 171
29X-RAY DIFFRACTION29B172 - 184
30X-RAY DIFFRACTION30B185 - 202
31X-RAY DIFFRACTION31B203 - 210
32X-RAY DIFFRACTION32B211 - 221
33X-RAY DIFFRACTION33B222 - 230
34X-RAY DIFFRACTION34C81 - 93
35X-RAY DIFFRACTION35C94 - 102
36X-RAY DIFFRACTION36C103 - 114
37X-RAY DIFFRACTION37C115 - 119
38X-RAY DIFFRACTION38C120 - 132
39X-RAY DIFFRACTION39C133 - 140
40X-RAY DIFFRACTION40C141 - 149
41X-RAY DIFFRACTION41C150 - 159
42X-RAY DIFFRACTION42D81 - 86
43X-RAY DIFFRACTION43D87 - 94
44X-RAY DIFFRACTION44D95 - 100
45X-RAY DIFFRACTION45D101 - 113
46X-RAY DIFFRACTION46D114 - 130
47X-RAY DIFFRACTION47D131 - 142
48X-RAY DIFFRACTION48D143 - 149
49X-RAY DIFFRACTION49D150 - 159
50X-RAY DIFFRACTION50E34 - 58
51X-RAY DIFFRACTION51E59 - 74
52X-RAY DIFFRACTION52E75 - 88
53X-RAY DIFFRACTION53E89 - 100
54X-RAY DIFFRACTION54E101 - 116
55X-RAY DIFFRACTION55E117 - 124
56X-RAY DIFFRACTION56E125 - 129
57X-RAY DIFFRACTION57E130 - 136
58X-RAY DIFFRACTION58E137 - 144
59X-RAY DIFFRACTION59E145 - 153
60X-RAY DIFFRACTION60E154 - 163
61X-RAY DIFFRACTION61E164 - 174
62X-RAY DIFFRACTION62E175 - 189
63X-RAY DIFFRACTION63E190 - 202
64X-RAY DIFFRACTION64E203 - 221
65X-RAY DIFFRACTION65E222 - 228
66X-RAY DIFFRACTION66F34 - 43
67X-RAY DIFFRACTION67F44 - 51
68X-RAY DIFFRACTION68F52 - 61
69X-RAY DIFFRACTION69F62 - 71
70X-RAY DIFFRACTION70F72 - 81
71X-RAY DIFFRACTION71F82 - 88
72X-RAY DIFFRACTION72F89 - 99
73X-RAY DIFFRACTION73F100 - 109
74X-RAY DIFFRACTION74F110 - 122
75X-RAY DIFFRACTION75F123 - 135
76X-RAY DIFFRACTION76F136 - 150
77X-RAY DIFFRACTION77F151 - 161
78X-RAY DIFFRACTION78F162 - 181
79X-RAY DIFFRACTION79F182 - 199
80X-RAY DIFFRACTION80F200 - 221
81X-RAY DIFFRACTION81F222 - 230
82X-RAY DIFFRACTION82G80 - 95
83X-RAY DIFFRACTION83G96 - 102
84X-RAY DIFFRACTION84G103 - 113
85X-RAY DIFFRACTION85G114 - 120
86X-RAY DIFFRACTION86G121 - 132
87X-RAY DIFFRACTION87G133 - 142
88X-RAY DIFFRACTION88G143 - 149
89X-RAY DIFFRACTION89G150 - 159
90X-RAY DIFFRACTION90H83 - 94
91X-RAY DIFFRACTION91H95 - 100
92X-RAY DIFFRACTION92H101 - 111
93X-RAY DIFFRACTION93H112 - 117
94X-RAY DIFFRACTION94H118 - 124
95X-RAY DIFFRACTION95H125 - 131
96X-RAY DIFFRACTION96H133 - 149
97X-RAY DIFFRACTION97H150 - 158
98X-RAY DIFFRACTION98I34 - 54
99X-RAY DIFFRACTION99I55 - 73
100X-RAY DIFFRACTION100I74 - 81
101X-RAY DIFFRACTION101I82 - 96
102X-RAY DIFFRACTION102I97 - 121
103X-RAY DIFFRACTION103I122 - 127
104X-RAY DIFFRACTION104I128 - 135
105X-RAY DIFFRACTION105I136 - 144
106X-RAY DIFFRACTION106I145 - 155
107X-RAY DIFFRACTION107I156 - 164
108X-RAY DIFFRACTION108I165 - 173
109X-RAY DIFFRACTION109I174 - 185
110X-RAY DIFFRACTION110I186 - 199
111X-RAY DIFFRACTION111I200 - 214
112X-RAY DIFFRACTION112I215 - 221
113X-RAY DIFFRACTION113I222 - 228
114X-RAY DIFFRACTION114J34 - 39
115X-RAY DIFFRACTION115J40 - 46
116X-RAY DIFFRACTION116J47 - 58
117X-RAY DIFFRACTION117J59 - 73
118X-RAY DIFFRACTION118J74 - 81
119X-RAY DIFFRACTION119J82 - 100
120X-RAY DIFFRACTION120J101 - 117
121X-RAY DIFFRACTION121J118 - 124
122X-RAY DIFFRACTION122J125 - 137
123X-RAY DIFFRACTION123J138 - 146
124X-RAY DIFFRACTION124J147 - 154
125X-RAY DIFFRACTION125J155 - 169
126X-RAY DIFFRACTION126J170 - 183
127X-RAY DIFFRACTION127J184 - 205
128X-RAY DIFFRACTION128J206 - 221
129X-RAY DIFFRACTION129J222 - 230
130X-RAY DIFFRACTION130K81 - 93
131X-RAY DIFFRACTION131K94 - 103
132X-RAY DIFFRACTION132K104 - 113
133X-RAY DIFFRACTION133K114 - 119
134X-RAY DIFFRACTION134K120 - 132
135X-RAY DIFFRACTION135K133 - 143
136X-RAY DIFFRACTION136K144 - 149
137X-RAY DIFFRACTION137K150 - 160
138X-RAY DIFFRACTION138L80 - 88
139X-RAY DIFFRACTION139L89 - 95
140X-RAY DIFFRACTION140L96 - 104
141X-RAY DIFFRACTION141L105 - 116
142X-RAY DIFFRACTION142L117 - 132
143X-RAY DIFFRACTION143L133 - 141
144X-RAY DIFFRACTION144L142 - 150
145X-RAY DIFFRACTION145L151 - 159
146X-RAY DIFFRACTION146M34 - 52
147X-RAY DIFFRACTION147M53 - 61
148X-RAY DIFFRACTION148M62 - 68
149X-RAY DIFFRACTION149M69 - 74
150X-RAY DIFFRACTION150M75 - 90
151X-RAY DIFFRACTION151M91 - 100
152X-RAY DIFFRACTION152M101 - 121
153X-RAY DIFFRACTION153M122 - 131
154X-RAY DIFFRACTION154M132 - 144
155X-RAY DIFFRACTION155M145 - 150
156X-RAY DIFFRACTION156M151 - 159
157X-RAY DIFFRACTION157M160 - 175
158X-RAY DIFFRACTION158M176 - 190
159X-RAY DIFFRACTION159M191 - 202
160X-RAY DIFFRACTION160M203 - 221
161X-RAY DIFFRACTION161M222 - 229
162X-RAY DIFFRACTION162N34 - 42
163X-RAY DIFFRACTION163N43 - 51
164X-RAY DIFFRACTION164N52 - 61
165X-RAY DIFFRACTION165N62 - 66
166X-RAY DIFFRACTION166N67 - 72
167X-RAY DIFFRACTION167N73 - 98
168X-RAY DIFFRACTION168N99 - 118
169X-RAY DIFFRACTION169N119 - 126
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171X-RAY DIFFRACTION171N137 - 146
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173X-RAY DIFFRACTION173N164 - 181
174X-RAY DIFFRACTION174N182 - 199
175X-RAY DIFFRACTION175N200 - 207
176X-RAY DIFFRACTION176N208 - 221
177X-RAY DIFFRACTION177N222 - 230
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179X-RAY DIFFRACTION179O87 - 95
180X-RAY DIFFRACTION180O96 - 105
181X-RAY DIFFRACTION181O106 - 117
182X-RAY DIFFRACTION182O118 - 132
183X-RAY DIFFRACTION183O133 - 141
184X-RAY DIFFRACTION184O142 - 149
185X-RAY DIFFRACTION185O150 - 160
186X-RAY DIFFRACTION186P84 - 95
187X-RAY DIFFRACTION187P96 - 104
188X-RAY DIFFRACTION188P105 - 116
189X-RAY DIFFRACTION189P117 - 125
190X-RAY DIFFRACTION190P126 - 134
191X-RAY DIFFRACTION191P135 - 144
192X-RAY DIFFRACTION192P145 - 150
193X-RAY DIFFRACTION193P151 - 158
194X-RAY DIFFRACTION194R1 - 5
195X-RAY DIFFRACTION195S1 - 5

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