PDB-3p6y: CF Im25-CF Im68-UGUAA complex

Basic information

• Entry: Database: PDB / ID: 3p6y
• Title: CF Im25-CF Im68-UGUAA complex

Components

• 5'-R(*UP*GP*UP*AP*A)-3'
• Cleavage and polyadenylation specificity factor subunit 5
• Cleavage and polyadenylation specificity factor subunit 6

• Keywords: RNA BINDING PROTEIN/RNA / RRM domain / RNA binding / nuclear / RNA BINDING PROTEIN-RNA complex

Function / homology

Function:

exon-exon junction complex binding / positive regulation of pro-B cell differentiation / positive regulation of RNA export from nucleus / mRNA cleavage factor complex / interchromatin granule / co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway / perichromatin fibrils / Processing of Intronless Pre-mRNAs / mRNA alternative polyadenylation / mRNA cleavage and polyadenylation specificity factor complex / positive regulation of stem cell differentiation / mRNA 3'-UTR AU-rich region binding / mRNA 3'-end processing / Signaling by cytosolic FGFR1 fusion mutants / paraspeckles / mRNA 3'-end processing / RNA Polymerase II Transcription Termination / post-transcriptional regulation of gene expression / protein heterotetramerization / ribosomal large subunit binding / Processing of Capped Intron-Containing Pre-mRNA / Signaling by FGFR1 in disease / protein tetramerization / centriolar satellite / histone deacetylase binding / mRNA processing / cell differentiation / nuclear speck / nuclear body / ribonucleoprotein complex / mRNA binding / chromatin binding / centrosome / protein homodimerization activity / RNA binding / nucleoplasm / membrane / identical protein binding / nucleus / cytoplasm

Domain/homology:

Cleavage and polyadenylation specificity factor subunit 6 / CPSF6/7 family / : / CPSF6-like, RSLD domain, N-terminal region / Cleavage/polyadenylation specificity factor subunit 5 / Nucleotide hydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nucleoside Triphosphate Pyrophosphohydrolase / Nudix hydrolase domain profile. / NUDIX hydrolase domain / RRM (RNA recognition motif) domain / NUDIX hydrolase-like domain superfamily / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / Alpha-Beta Complex / 2-Layer Sandwich / Alpha Beta

Component:

RNA / Cleavage and polyadenylation specificity factor subunit 5 / Cleavage and polyadenylation specificity factor subunit 6

• Biological species: Homo sapiens (human)
• Method: X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.9 Å
• Authors: Li, H. / Tong, S. / Li, X. / Shi, H. / Gao, Y. / Ge, H. / Niu, L. / Teng, M.
• Citation: Journal: To be Published; Title: Structural basis of pre-mRNA recognition by the human cleavage factor Im complex; Authors: Li, H. / Tong, S. / Li, X. / Shi, H. / Gao, Y. / Ge, H. / Niu, L. / Teng, M.

History

Deposition	Oct 11, 2010	Deposition site: RCSB / Processing site: PDBJ
Revision 1.0	Nov 3, 2010	Provider: repository / Type: Initial release
Revision 1.1	Jul 13, 2011	Group: Version format compliance
Revision 1.2	Nov 1, 2023	Group: Data collection / Database references / Refinement description Category: chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details

Assembly

Deposited unit

A: Cleavage and polyadenylation specificity factor subunit 5

B: Cleavage and polyadenylation specificity factor subunit 5

C: Cleavage and polyadenylation specificity factor subunit 6

D: Cleavage and polyadenylation specificity factor subunit 6

E: Cleavage and polyadenylation specificity factor subunit 5

F: Cleavage and polyadenylation specificity factor subunit 5

G: Cleavage and polyadenylation specificity factor subunit 6

H: Cleavage and polyadenylation specificity factor subunit 6

I: Cleavage and polyadenylation specificity factor subunit 5

J: Cleavage and polyadenylation specificity factor subunit 5

K: Cleavage and polyadenylation specificity factor subunit 6

L: Cleavage and polyadenylation specificity factor subunit 6

M: Cleavage and polyadenylation specificity factor subunit 5

N: Cleavage and polyadenylation specificity factor subunit 5

O: Cleavage and polyadenylation specificity factor subunit 6

P: Cleavage and polyadenylation specificity factor subunit 6

Q: 5'-R(*UP*GP*UP*AP*A)-3'

R: 5'-R(*UP*GP*UP*AP*A)-3'

S: 5'-R(*UP*GP*UP*AP*A)-3'

T: 5'-R(*UP*GP*UP*AP*A)-3'

U: 5'-R(*UP*GP*UP*AP*A)-3'

V: 5'-R(*UP*GP*UP*AP*A)-3'

W: 5'-R(*UP*GP*UP*AP*A)-3'

Summary:

• 281 kDa, 23 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	281,105	23
Polymers	281,105	23
Non-polymers	0	0
Water	1,243	69

1

A: Cleavage and polyadenylation specificity factor subunit 5

B: Cleavage and polyadenylation specificity factor subunit 5

C: Cleavage and polyadenylation specificity factor subunit 6

D: Cleavage and polyadenylation specificity factor subunit 6

Q: 5'-R(*UP*GP*UP*AP*A)-3'

R: 5'-R(*UP*GP*UP*AP*A)-3'

Summary:

• defined by author
• 70.7 kDa, 6 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	70,669	6
Polymers	70,669	6
Non-polymers	0	0
Water	72	4

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

2

E: Cleavage and polyadenylation specificity factor subunit 5

F: Cleavage and polyadenylation specificity factor subunit 5

G: Cleavage and polyadenylation specificity factor subunit 6

H: Cleavage and polyadenylation specificity factor subunit 6

S: 5'-R(*UP*GP*UP*AP*A)-3'

W: 5'-R(*UP*GP*UP*AP*A)-3'

Summary:

• defined by author
• 70.7 kDa, 6 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	70,669	6
Polymers	70,669	6
Non-polymers	0	0
Water	72	4

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

3

I: Cleavage and polyadenylation specificity factor subunit 5

J: Cleavage and polyadenylation specificity factor subunit 5

K: Cleavage and polyadenylation specificity factor subunit 6

L: Cleavage and polyadenylation specificity factor subunit 6

T: 5'-R(*UP*GP*UP*AP*A)-3'

Summary:

• defined by author
• 69.1 kDa, 5 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	69,098	5
Polymers	69,098	5
Non-polymers	0	0
Water	72	4

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

4

M: Cleavage and polyadenylation specificity factor subunit 5

N: Cleavage and polyadenylation specificity factor subunit 5

O: Cleavage and polyadenylation specificity factor subunit 6

P: Cleavage and polyadenylation specificity factor subunit 6

U: 5'-R(*UP*GP*UP*AP*A)-3'

V: 5'-R(*UP*GP*UP*AP*A)-3'

Summary:

• defined by author
• 70.7 kDa, 6 polymers

Component details:

	Theoretical mass	Number of molelcules
Total (without water)	70,669	6
Polymers	70,669	6
Non-polymers	0	0
Water	72	4

Symmetry operations:

Type	Name	Symmetry operation	Number
identity operation	1_555	x,y,z	1

Unit cell

Length a, b, c (Å)	104.783, 129.419, 111.159
Angle α, β, γ (deg.)	90.00, 94.01, 90.00
Int Tables number	4
Space group name H-M	P1211

Components

#1: Protein

A B E F I J M N
Cleavage and polyadenylation specificity factor subunit 5 / Cleavage factor Im 25 / Cleavage and polyadenylation specificity factor 25 kDa subunit / CPSF 25 kDa subunit / Nucleoside diphosphate-linked moiety X motif 21 / Nudix motif 21 / Pre-mRNA cleavage factor Im 25 kDa subunit

Details:

Mass: 23614.115 Da / Num. of mol.: 8 / Fragment: UNP residues 34-227
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: NUDT21, CFIM25, CPSF25, CPSF5 / Production host: Escherichia coli (E. coli) / References: UniProt: O43809

#2: Protein

C D G H K L O P
Cleavage and polyadenylation specificity factor subunit 6 / Cleavage factor Im 68 / Cleavage and polyadenylation specificity factor 68 kDa subunit / CF Im68 / CPSF 68 kDa subunit / Pre-mRNA cleavage factor Im 68 kDa subunit / Protein HPBRII-4/7

Details:

Mass: 10149.415 Da / Num. of mol.: 8 / Fragment: UNP residues 80-161 / Mutation: C159S
Source method: isolated from a genetically manipulated source
Source: (gene. exp.) Homo sapiens (human) / Gene: CPSF6, CFIM68 / Production host: Escherichia coli (E. coli) / References: UniProt: Q16630

#3: RNA chain

Q R S T U V W
5'-R(*UP*GP*UP*AP*A)-3'

Details:

Mass: 1570.992 Da / Num. of mol.: 7 / Source method: obtained synthetically

#4: Water

ChemComp-HOH / water

Details:

Mass: 18.015 Da / Num. of mol.: 69 / Source method: isolated from a natural source / Formula: H₂O

Experimental details

Experiment

• Experiment: Method: X-RAY DIFFRACTION / Number of used crystals: 1

Sample preparation

• Crystal: Density Matthews: 2.67 ų/Da / Density % sol: 54.01 %
• Crystal grow: Temperature: 283 K / Method: vapor diffusion, sitting drop / pH: 5 ; Details: 15% PEG 3350, 9% dioxane and 0.1M sodium citrate, pH 5.0, VAPOR DIFFUSION, SITTING DROP, temperature 283K

Data collection

• Diffraction: Mean temperature: 100 K
• Diffraction source: Source: SYNCHROTRON / Site: SSRF / Beamline: BL17U
• Detector: Type: MARMOSAIC 225 mm CCD / Detector: CCD
• Radiation: Monochromator: GRAPHITE / Protocol: SINGLE WAVELENGTH / Monochromatic (M) / Laue (L): M / Scattering type: x-ray
• Radiation wavelength: Relative weight: 1
• Reflection: Resolution: 2.9→50 Å / Num. all: 62810 / Num. obs: 59607 / % possible obs: 95.92 % / Observed criterion σ(F): 2 / Observed criterion σ(I): 2
• Reflection shell: Resolution: 2.9→2.978 Å / % possible all: 95.92

Processing

Software

Name	Version	Classification
HKL-2000		data collection
PHASES		phasing
REFMAC	5.5.0102	refinement
HKL-2000		data reduction
HKL-2000		data scaling

Refinement

Method to determine structure: MOLECULAR REPLACEMENT
Starting model: 3P5T

3p5t

Resolution: 2.9→50 Å / Cor.coef. F_o:F_c: 0.914 / Cor.coef. F_o:F_c free: 0.88 / SU B: 40.548 / SU ML: 0.353 / Cross valid method: THROUGHOUT / σ(F): 2 / ESU R Free: 0.448 / Stereochemistry target values: MAXIMUM LIKELIHOOD

	Rfactor	Num. reflection	% reflection	Selection details
Rfree	0.27548	3182	5.1 %	RANDOM
Rwork	0.22632	-	-	-
all	0.239	62810	-	-
obs	0.22877	59607	95.92 %	-

• Solvent computation: Ion probe radii: 0.8 Å / Shrinkage radii: 0.8 Å / VDW probe radii: 1.4 Å / Solvent model: MASK

Displacement parameters

B_iso mean: 61.269 Ų

	Baniso -1	Baniso -2	Baniso -3
1-	-2.38 Å2	0 Å2	0.23 Å2
2-	-	-2.7 Å2	0 Å2
3-	-	-	5.12 Å2

Refinement step

Cycle: LAST / Resolution: 2.9→50 Å

	Protein	Nucleic acid	Ligand	Solvent	Total
Num. atoms	17049	449	0	69	17567

Refine LS restraints

Refine-ID	Type	Dev ideal	Dev ideal target	Number
X-RAY DIFFRACTION	r_bond_refined_d	0.006	0.022	18008
X-RAY DIFFRACTION	r_bond_other_d
X-RAY DIFFRACTION	r_angle_refined_deg	1.005	1.992	24625
X-RAY DIFFRACTION	r_angle_other_deg
X-RAY DIFFRACTION	r_dihedral_angle_1_deg	4.752	5	2176
X-RAY DIFFRACTION	r_dihedral_angle_2_deg	34.821	23.866	776
X-RAY DIFFRACTION	r_dihedral_angle_3_deg	15.331	15	2673
X-RAY DIFFRACTION	r_dihedral_angle_4_deg	15.754	15	92
X-RAY DIFFRACTION	r_chiral_restr	0.066	0.2	2731
X-RAY DIFFRACTION	r_gen_planes_refined	0.004	0.021	13757
X-RAY DIFFRACTION	r_gen_planes_other
X-RAY DIFFRACTION	r_nbd_refined
X-RAY DIFFRACTION	r_nbd_other
X-RAY DIFFRACTION	r_nbtor_refined
X-RAY DIFFRACTION	r_nbtor_other
X-RAY DIFFRACTION	r_xyhbond_nbd_refined
X-RAY DIFFRACTION	r_xyhbond_nbd_other
X-RAY DIFFRACTION	r_metal_ion_refined
X-RAY DIFFRACTION	r_metal_ion_other
X-RAY DIFFRACTION	r_symmetry_vdw_refined
X-RAY DIFFRACTION	r_symmetry_vdw_other
X-RAY DIFFRACTION	r_symmetry_hbond_refined
X-RAY DIFFRACTION	r_symmetry_hbond_other
X-RAY DIFFRACTION	r_symmetry_metal_ion_refined
X-RAY DIFFRACTION	r_symmetry_metal_ion_other
X-RAY DIFFRACTION	r_mcbond_it	0.261	1.5	10951
X-RAY DIFFRACTION	r_mcbond_other
X-RAY DIFFRACTION	r_mcangle_it	0.484	2	17535
X-RAY DIFFRACTION	r_scbond_it	0.464	3	7057
X-RAY DIFFRACTION	r_scangle_it	0.828	4.5	7090
X-RAY DIFFRACTION	r_rigid_bond_restr
X-RAY DIFFRACTION	r_sphericity_free
X-RAY DIFFRACTION	r_sphericity_bonded

LS refinement shell

Resolution: 2.903→2.978 Å / Total num. of bins used: 20

	Rfactor	Num. reflection	% reflection
Rfree	0.359	176	-
Rwork	0.305	3314	-
obs	-	-	72.42 %

Refinement TLS params.

Method: refined / Refine-ID: X-RAY DIFFRACTION

ID	L11 (°2)	L12 (°2)	L13 (°2)	L22 (°2)	L23 (°2)	L33 (°2)	S11 (Å °)	S12 (Å °)	S13 (Å °)	S21 (Å °)	S22 (Å °)	S23 (Å °)	S31 (Å °)	S32 (Å °)	S33 (Å °)	T11 (Å2)	T12 (Å2)	T13 (Å2)	T22 (Å2)	T23 (Å2)	T33 (Å2)	Origin x (Å)	Origin y (Å)	Origin z (Å)
1	7.3275	-1.0578	-0.9994	0.9042	-0.4505	3.1818	-0.0256	-0.0544	-0.2886	-0.033	-0.0499	0.298	0.0942	-0.2424	0.0756	0.3934	0.015	-0.0105	0.2667	-0.028	0.3262	13.4941	2.0623	-12.7649
2	5.2758	-0.0898	-0.9679	1.3989	0.9326	0.9148	0.5224	-0.0158	0.4414	0.0386	0.0123	-0.7922	-0.3	0.0479	-0.5347	0.4944	-0.0132	-0.0587	0.3297	0.0318	0.496	26.5406	20.0456	-20.6346
3	4.9942	2.402	-2.0732	2.9763	0.4703	2.3093	-0.0455	0.1036	-0.0636	0.2373	0.1086	-0.4204	0.1	0.2149	-0.0631	0.4227	-0.0877	-0.0251	0.3257	0.0286	0.4529	19.7397	38.2019	-8.075
4	3.5635	1.8388	1.5368	9.3441	0.8485	0.9365	-0.2012	0.3819	0.4789	0.2555	0.1759	0.0862	-0.345	-0.0145	0.0253	0.4153	0.0233	0.1329	0.3414	0.0564	0.3762	9.8786	34.687	-10.8562
5	5.1829	-5.3162	0.2879	7.8415	-2.8535	5.2592	-0.0833	-0.0516	0.0839	-0.0108	0.0886	-0.2662	0.2344	0.0293	-0.0054	0.1934	-0.0631	-0.0036	0.2698	-0.0766	0.3067	19.8964	6.0534	-8.7757
6	10.8835	6.1115	1.2818	3.8061	0.5053	6.1619	0.0485	-0.2091	0.7492	0.3011	-0.0957	-0.0054	-0.7644	0.7274	0.0472	0.467	-0.0179	-0.1761	0.2747	-0.0212	0.6081	29.167	20.4418	-8.6949
7	7.1268	-3.1887	3.9183	5.0995	-2.0662	2.6199	-0.0385	0.1459	0.6841	-0.2541	-0.2294	-0.0444	-0.1546	-0.069	0.2678	0.3421	0.0318	0.0596	0.3663	0.0081	0.2884	12.7515	24.8885	-14.3004
8	2.8582	7.6076	-2.8948	22.0264	-5.9865	5.4547	-0.2294	0.045	0.1011	-0.6953	-0.2574	0.4434	-0.1289	-0.4863	0.4868	0.2904	-0.0042	-0.0676	0.4198	-0.001	0.2927	10.6762	21.8861	-19.8665
9	5.2254	-2.2837	-2.8354	8.8439	5.754	15.9378	-0.1403	0.5123	0.0429	-0.8361	-0.1745	0.0916	-0.5896	0.2613	0.3148	0.312	-0.0109	-0.0151	0.3818	0.0623	0.3288	19.6395	16.4634	-25.4689
10	2.6625	-0.723	-0.0735	1.0582	3.5549	17.9393	0.0054	0.6559	-0.5083	-0.1254	-0.3002	0.1102	0.6788	-0.5637	0.2948	0.5048	-0.0133	0.036	0.3504	-0.021	0.3195	9.5958	13.1712	-16.355
11	0.1309	0.5238	0.2902	5.7772	1.6996	1.7493	-0.0484	0.0441	0.1178	0.4021	0.084	-0.0812	-0.1872	0.1793	-0.0356	0.2581	0.0112	0.0065	0.259	0.0231	0.3451	12.6166	30.5317	-0.5677
12	1.1514	0.7367	-0.6935	1.6581	0.7947	2.6414	0.059	0.1855	0.2891	-0.1143	-0.0081	-0.1449	-0.2283	-0.1505	-0.051	0.195	0.0145	-0.0084	0.2087	0.0462	0.4544	9.356	31.3617	2.9603
13	2.9967	-1.7771	-0.8917	1.3608	0.1622	1.6222	0.0349	0.2486	-0.0326	-0.1381	-0.0674	0.0422	0.0844	-0.0611	0.0326	0.269	-0.0217	-0.0256	0.2814	0.0551	0.2204	15.2668	14.6992	-15.1851
14	2.3624	1.9575	-2.8397	2.7551	-3.4452	7.8227	0.1714	-0.0497	0.1089	0.0672	-0.2184	-0.1384	-0.314	0.6205	0.047	0.2178	0.0312	0.0291	0.2173	0.0286	0.2459	26.1172	13.2615	-7.7226
15	4.0575	3.3088	-0.6013	3.9487	-0.242	1.4573	0.0557	-0.1912	-0.118	0.1147	-0.107	-0.1392	-0.1062	0.0532	0.0514	0.2454	0.039	-0.0025	0.2257	-0.0064	0.1924	18.2183	14.6772	0.4999
16	4.805	-6.3056	-0.2674	8.8507	-0.4771	3.7453	-0.1823	-0.0418	-0.1758	0.1128	0.1271	-0.2132	0.7088	0.0482	0.0552	0.3035	-0.0276	-0.0586	0.2309	-0.0161	0.5164	12.8308	-0.5854	-8.6128
17	8.4909	0.344	-0.6441	6.4551	0.8654	9.4648	-0.2153	0.5868	-0.2071	-0.308	-0.1832	-0.1333	0.5504	-0.1298	0.3986	0.1914	-0.0161	0.0184	0.1984	0.0323	0.2425	-6.6967	19.8293	4.0062
18	0.3797	-1.056	0.0334	10.0152	-6.1109	6.1175	-0.1988	-0.2079	-0.021	1.1581	0.2455	-0.3314	-0.4132	-0.1455	-0.0467	0.2943	0.0429	-0.0245	0.4371	0.0631	0.2915	-10.6855	14.9577	21.2046
19	4.2676	-0.6761	-1.9669	0.2125	-0.1084	2.8913	-0.0247	0.5986	0.414	-0.0626	0.0114	-0.0745	0.2697	-0.4554	0.0134	0.469	0.0211	-0.0414	0.4559	0.0405	0.4202	5.2288	-0.9343	26.8235
20	5.2529	3.156	-0.406	2.0406	-0.7268	10.1247	0.0844	-0.184	0.0183	0.1281	0.1187	-0.0453	0.3935	0.0059	-0.2031	0.3892	0.0957	-0.055	0.492	0.0016	0.3242	12.1878	-9.7155	18.6822
21	2.1577	-4.2227	0.3124	12.5566	-1.7163	0.7683	-0.2462	-0.1371	-0.1657	0.5329	0.2738	-0.1374	0.139	0.1553	-0.0275	0.2153	-0.0288	-0.0244	0.2921	-0.0088	0.1876	1.7358	7.2106	10.9621
22	2.3095	0.7288	-0.8298	3.2328	-1.6926	5.9152	-0.1503	-0.2586	0.04	0.2878	0.1291	-0.2289	-0.0235	-0.0164	0.0212	0.1857	0.0027	-0.0201	0.2744	-0.0447	0.1904	0.7848	20.0383	15.0157
23	1.4326	1.5856	0.7436	3.256	1.9134	3.7373	0.3163	-0.1535	0.0102	0.7727	-0.0485	-0.0542	0.204	0.2418	-0.2678	0.4219	0.0244	0.0281	0.3291	0.0345	0.2438	4.9139	7.3038	19.4905
24	3.9644	-5.504	2.797	13.3327	-3.4062	5.9545	0.0674	0.2555	-0.5564	-0.6215	-0.0872	0.5848	0.5847	-0.2403	0.0197	0.3114	-0.0824	0.0106	0.3538	0.0353	0.3444	-3.363	-4.3598	8.1419
25	6.3748	0.5304	-0.7708	1.2983	1.1595	1.673	-0.042	-0.2915	-0.2144	0.1685	0.1444	0.0623	-0.0593	-0.0064	-0.1024	0.3737	0.0287	0.0687	0.3897	0.0889	0.3231	-10.9196	4.2958	17.1593
26	7.8217	-0.2874	-2.1713	0.3591	-0.342	1.3504	0.1527	0.3148	-0.0412	0.0086	0.0376	0.2688	-0.0138	-0.3854	-0.1903	0.2773	-0.042	0.0291	0.3235	-0.0452	0.2937	-3.2929	7.1247	6.2968
27	1.6065	0.4462	-1.8005	2.8095	-2.63	3.8003	-0.0075	-0.0968	-0.1761	0.1756	-0.0449	-0.0143	-0.0771	0.0934	0.0524	0.2325	-0.021	-0.0107	0.1945	0.003	0.1874	17.1312	0.0721	11.2583
28	1.2163	-0.742	-0.5846	1.9825	0.3625	0.6284	-0.1081	-0.1767	-0.305	0.098	0.0362	0.116	0.1278	-0.0981	0.0719	0.1929	-0.0248	-0.0151	0.1999	0.0086	0.1775	17.5521	-3.526	5.359
29	8.1978	-6.2701	-0.6584	5.1715	1.0799	1.4671	-0.0305	0.1215	0.1348	0.0654	-0.0181	0.034	-0.0583	-0.1767	0.0486	0.2333	-0.0561	0.0104	0.2802	0.0483	0.2627	-5.008	10.924	8.1951
30	3.8645	3.0615	-3.0874	2.4887	-2.4878	2.567	0.2164	-0.45	-0.052	0.2807	-0.2689	-0.0021	-0.1779	0.2012	0.0526	0.3137	0.0359	0.0002	0.3112	0.0022	0.2365	1.2722	16.1654	18.8907
31	3.0476	-0.9645	2.5144	3.0282	0.317	4.5459	-0.0868	-0.0956	0.2618	0.2524	0.0232	-0.2062	-0.0952	0.4567	0.0635	0.2212	-0.0117	-0.0061	0.252	-0.0298	0.2355	14.4314	16.1528	15.4693
32	3.6349	-1.2275	1.7415	2.5125	-1.5368	5.8906	0.082	0.2581	0.0165	-0.0674	-0.0616	0.018	0.1482	0.2724	-0.0205	0.1952	-0.0124	0.0218	0.1963	-0.022	0.2167	8.1017	15.2262	5.8712
33	4.0077	-2.4337	0.6026	5.5523	-0.152	0.2535	0.0705	-0.112	0.442	0.2364	-0.0756	-0.0883	-0.0531	-0.209	0.0051	0.2185	-0.01	0.0058	0.3232	0.0352	0.2168	-6.6168	24.6756	4.4522
34	1.3219	-1.8637	0.9432	3.6434	-1.9797	1.1343	-0.2117	-0.2708	-0.0432	0.498	0.1869	-0.054	-0.2029	-0.122	0.0248	0.2431	-0.028	-0.0365	0.2468	-0.003	0.198	33.7402	-7.4877	4.5834
35	5.732	-0.4148	-5.1328	12.9734	-2.4883	8.0619	0.132	0.0506	0.0655	-0.3214	0.1818	0.3239	-0.0105	-0.3586	-0.3138	0.2421	-0.0296	-0.0123	0.226	0.0115	0.2499	28.2444	-16.0316	2.3971
36	0.0567	0.3284	-0.1705	2.2636	-1.1761	0.6352	0.0129	-0.0098	0.0789	0.2693	0.2199	0.4342	-0.0685	-0.1584	-0.2328	0.3225	0.0151	0.0199	0.2915	-0.0174	0.3362	30.3469	-17.4953	8.6071
37	16.4607	-12.2905	0.3117	11.1204	1.572	3.9248	-0.2964	-0.805	-0.039	0.5572	0.4572	-0.0274	0.8254	-0.0838	-0.1607	0.329	0.0114	0.0299	0.2888	0.0328	0.2579	27.5818	2.2888	11.162
38	1.1639	-2.5719	0.2582	6.6917	-0.3148	0.3666	-0.2306	-0.1154	0.102	0.475	0.1554	-0.1238	-0.0375	0.0029	0.0752	0.2994	0.0209	-0.0275	0.2544	-0.0135	0.2673	31.7104	-5.4818	9.0541
39	9.3254	-2.331	-9.0432	3.0608	0.3289	11.4547	-0.3526	0.6903	-0.1421	-0.1862	-0.0428	-0.2117	0.6547	-0.745	0.3954	0.4461	-0.0726	0.0242	0.3407	-0.0756	0.3454	40.0665	-22.7744	9.4145
40	9.3823	1.6921	0.0827	6.3069	2.5098	1.0769	-0.0129	0.1051	0.1158	-0.0533	0.0448	-0.3063	0.0394	0.0876	-0.0318	0.2655	0.0367	0.1097	0.2901	0.097	0.4666	40.0943	-15.5985	-0.1627
41	5.1118	1.1286	1.2973	3.4766	-0.3371	4.3859	-0.1793	0.0015	-0.0872	0.3662	-0.1261	-0.1015	-0.19	0.1854	0.3055	0.2758	0.0145	0.0196	0.2068	0.0171	0.3014	39.4227	-9.709	3.104
42	1.5746	3.1786	-2.7144	6.864	-5.7341	5.0885	0.1366	-0.3002	-0.2662	0.4857	-0.3959	-0.4489	-0.1283	0.3138	0.2593	0.3259	-0.04	-0.0307	0.2382	0.0282	0.3678	11.8519	50.0905	13.8805
43	4.8512	1.8101	0.4573	4.5555	0.255	1.0235	0.097	0.3073	-0.0664	-0.1327	-0.1869	-0.3309	-0.0681	0.1888	0.0899	0.325	0.0226	0.016	0.2903	-0.0609	0.2983	3.1536	37.4857	13.7402
44	4.669	0.7711	-2.693	12.3818	-1.1705	9.0587	0.3647	0.0566	0.4105	-0.2053	0.0999	0.5575	-0.7951	-0.2118	-0.4646	0.4171	-0.0036	-0.0031	0.3418	-0.066	0.5009	-0.2309	45.018	7.2881
45	0.161	-0.1668	0.0714	1.4374	-1.6954	2.1623	0.1233	0.1367	0.1364	0.2864	-0.075	0.0432	-0.463	-0.003	-0.0483	0.6157	0.1059	0.0971	0.5687	0.0452	0.5215	4.0918	51.9585	6.314
46	3.755	-4.1783	-1.736	13.6522	0.4647	1.287	-0.0189	0.0088	0.5382	-0.3765	0.1925	-0.9004	-0.2216	-0.1407	-0.1736	0.3816	-0.0219	-0.0437	0.3938	-0.0912	0.3709	12.5262	37.7022	12.0226
47	1.4783	3.4379	-3.0544	11.3348	-4.4792	13.0056	0.2258	0.2486	0.12	0.3847	0.033	-0.4568	-0.4365	-0.1428	-0.2587	0.5459	0.0063	0.0577	0.4228	0.023	0.5725	6.0878	58.8679	13.0149
48	4.0305	-1.0739	5.3842	10.0594	6.6394	14.2082	-0.0941	0.0174	-0.3995	-0.2702	0.0803	0.7022	-0.6563	-0.1652	0.0137	0.3447	0.1216	0.1331	0.6423	0.2645	0.6317	-1.6978	49.7957	18.133
49	2.0926	-2.496	-1.7312	3.0925	1.5605	9.3036	0.1567	-0.1994	0.2361	-0.1259	-0.0084	-0.2005	-0.3434	0.3573	-0.1483	0.5332	-0.0939	0.124	0.6943	-0.1963	0.4234	4.8973	46.5533	18.9426
50	2.1903	-0.1828	-0.6888	3.6239	0.4693	2.0827	-0.0404	-0.1985	0.0802	0.1153	0.0402	0.0398	0.1027	0.0085	0.0003	0.3018	-0.02	-0.0437	0.3433	-0.0031	0.2217	27.4184	-16.0776	72.348
51	13.3446	4.4037	-2.0894	4.8935	-0.8817	0.3817	-0.0742	-0.0184	0.2109	0.0875	0.1702	0.2326	0.0965	0.0796	-0.0961	0.3831	0.0787	0.0052	0.2888	-0.0541	0.3782	30.8678	11.4053	65.6301
52	2.3169	4.1308	-0.193	14.7034	0.5581	1.776	-0.0992	-0.0382	0.36	0.1704	0.2003	0.7204	-0.1442	0.0305	-0.1012	0.2365	0.0368	-0.0162	0.3274	-0.0269	0.2429	33.6989	-9.7445	66.2243
53	3.3443	2.0755	0.1396	2.5406	0.9513	4.5815	-0.1089	0.0432	-0.0107	-0.0983	0.0328	0.0604	-0.0205	0.0723	0.0761	0.2171	0.0025	-0.0018	0.2794	0.0126	0.2729	24.5019	-18.9565	63.341
54	4.493	4.4818	2.852	5.058	2.2964	5.2466	-0.1551	-0.3763	0.5951	-0.0328	-0.2195	0.3651	-0.3291	-0.1905	0.3747	0.3979	0.0828	-0.0033	0.3639	-0.1407	0.455	30.7655	-3.4553	68.4483
55	0.7235	1.2177	2.0437	8.7109	6.0816	7.709	-0.0023	0.1175	0.1236	0.117	-0.3354	-0.6159	0.0764	0.7662	0.3377	0.2626	0.0622	-0.05	0.8017	0.1139	0.3801	38.9487	-6.7217	74.5781
56	8.9152	4.1665	-9.3704	31.378	3.3663	33.1644	0.1259	-0.2548	0.6005	0.1289	-0.2216	0.6989	-1.2611	0.077	0.0957	0.3622	0.0375	-0.0464	0.3679	-0.0307	0.319	29.6479	-8.9312	76.3768
57	14.749	-2.8628	-15.6534	1.6885	1.5984	20.5495	-0.7245	-0.9974	-0.8288	0.6783	0.4939	0.3666	-0.2546	0.2765	0.2305	0.6064	0.0727	0.0698	0.6631	-0.0015	0.4597	28.3401	-15.803	85.2444
58	3.2166	-2.1872	5.4408	5.8769	-3.7877	9.8152	0.2353	-0.0918	-0.3242	0.0807	-0.1024	-0.282	0.4762	0.291	-0.1329	0.3761	0.0583	-0.0916	0.5282	0.1629	0.5045	38.9751	-15.7283	72.9734
59	0.2702	-0.2163	-0.0023	7.5708	-1.8634	0.8203	0.0265	0.0086	0.0423	0.0354	-0.0628	-0.0705	-0.1016	-0.0011	0.0363	0.2693	0.0035	-0.0437	0.2657	-0.0506	0.4038	36.9777	0.422	57.7471
60	6.1084	-0.1245	-2.3208	4.1023	1.8233	2.809	0.3719	0.2151	0.2799	-0.172	-0.3709	0.2817	-0.4852	-0.1468	-0.001	0.3261	-0.05	-0.0212	0.2832	-0.0095	0.2759	36.2682	1.7408	52.7006
61	0.1724	-0.5865	-0.0025	3.9173	-0.4886	1.295	-0.0145	0.0663	0.1735	0.1137	0.0058	-0.2107	-0.3061	0.2767	0.0087	0.2836	-0.0465	-0.0178	0.3059	-0.0084	0.4194	40.1258	3.2679	58.7042
62	0.5298	1.005	-0.8735	3.7673	-1.6814	2.284	-0.1104	-0.238	-0.2715	0.1986	-0.1632	-0.2259	0.3682	0.2096	0.2735	0.2763	0.0312	0.0432	0.3511	0.0989	0.3053	30.2207	-17.6269	74.1674
63	0.9945	-0.7482	-1.6607	0.6249	1.3216	2.9099	0.023	0.1489	-0.0349	-0.0259	-0.1725	0.1329	-0.1239	-0.3804	0.1496	0.2218	0.0062	-0.0089	0.2298	-0.0365	0.216	22.9803	-15.4396	61.5711
64	2.441	-1.6465	-1.4974	3.6909	0.9177	1.9615	0.0421	0.3147	-0.2467	-0.1242	-0.0758	0.1114	-0.0514	0.0651	0.0336	0.2467	-0.0501	-0.0153	0.2738	-0.0323	0.2025	30.3599	-12.8868	54.9104
65	7.3821	8.8442	-2.7809	11.3989	-2.2632	8.081	-0.4349	0.1118	-0.2116	-0.3213	0.3542	0.3314	0.9922	-0.2472	0.0807	0.3171	0.0728	0.0342	0.3402	0.1174	0.59	36.1425	-28.1366	63.3073
66	4.8581	-0.7227	1.0271	3.1005	2.9679	3.9103	-0.1451	-0.2973	-0.0943	0.019	0.0612	0.1211	0.3266	-0.0867	0.0839	0.3045	0.0067	0.002	0.2096	-0.0602	0.319	55.2482	-7.1359	51.4264
67	1.2764	3.3632	1.1273	15.1338	13.3565	21.0016	-0.1798	0.4906	-0.0939	-1.1148	0.5138	-0.3177	-0.609	-0.3717	-0.334	0.3367	0.0474	0.0848	0.4818	0.0561	0.4257	59.1539	-11.9336	33.7985
68	19.1161	5.7449	-7.0442	2.2859	-0.8399	5.6113	0.0499	-0.105	0.8532	-0.0187	0.1285	0.3716	-0.1286	0.2647	-0.1783	0.5476	-0.0121	-0.0445	0.4295	0.0025	0.4712	44.1135	-26.7904	28.0302
69	4.7564	1.0934	-2.7261	11.8884	-3.7993	7.4736	0.0512	0.8105	0.0738	-0.7887	0.0434	0.0986	0.3949	-0.5283	-0.0945	0.3929	-0.0653	0.0314	0.4273	-0.0879	0.2866	36.4001	-35.7748	34.9931
70	2.9826	3.6199	2.413	9.4184	6.5841	5.3126	-0.2247	0.216	-0.1682	-0.4805	0.1913	0.0082	0.1699	-0.0756	0.0334	0.4147	-0.0654	0.0169	0.3381	-0.003	0.2443	42.2505	-33.5697	43.0733
71	2.4916	1.929	-0.541	4.7721	1.7168	2.44	-0.0933	0.0331	0.0841	-0.31	0.1362	-0.0208	-0.167	0.1073	-0.0429	0.218	-0.0177	-0.0187	0.2766	-0.0201	0.2414	51.1463	-8.0244	44.8454
72	2.696	0.6169	-0.6971	3.2031	1.2467	3.0434	-0.165	0.1867	0.0944	-0.4778	0.1113	0.1623	-0.2886	-0.0632	0.0536	0.2508	-0.0213	-0.0379	0.2675	0.0048	0.2402	47.7342	-6.4689	40.9218
73	2.5331	1.2661	-1.6415	0.7336	-0.8796	1.2733	-0.0284	0.3978	0.0626	-0.1952	0.1333	0.1263	0.0156	-0.2719	-0.1049	0.5341	0.0614	-0.0205	0.3903	-0.0079	0.3166	42.998	-16.098	34.5357
74	7.9235	4.0501	1.441	3.9512	-1.1132	2.7402	0.1706	-0.2153	-0.4778	0.1294	-0.1785	-0.419	0.627	0.1139	0.0078	0.6027	0.051	-0.0339	0.3269	-0.0413	0.3775	51.8616	-30.6273	45.6094
75	5.1881	0.6049	-1.3817	0.2292	-0.1956	0.3914	-0.1237	0.6368	0.2968	-0.2614	0.1495	-0.059	0.0969	-0.1284	-0.0258	0.4275	-0.0373	0.0526	0.3602	-0.05	0.3182	59.7681	-21.8112	37.1583
76	8.5592	0.8061	-0.384	0.7659	-0.4318	0.3874	-0.0362	-0.3245	-0.0325	0.0494	-0.0798	-0.339	-0.0645	0.233	0.116	0.2278	0.0076	0.0314	0.2925	-0.0545	0.2343	48.8643	-21.4023	48.4001
77	1.2164	-0.9976	-1.3532	2.8924	-0.0922	2.3526	0.0398	0.1916	-0.0671	-0.2843	0.0295	0.2634	0.0364	-0.1556	-0.0693	0.2349	-0.0133	-0.0041	0.2613	-0.0204	0.1682	30.7413	-26.543	44.5811
78	6.4443	2.9953	-0.9203	2.5189	-0.9766	0.6964	0.0421	-0.1236	-0.1208	-0.0418	-0.0815	-0.2373	-0.0235	0.1419	0.0395	0.2236	0.0192	0.0273	0.2057	-0.0384	0.1749	41.8252	-24.4514	48.4257
79	2.1763	-1.8692	-2.1172	2.1452	2.0334	2.3692	-0.1578	0.444	-0.0993	-0.0939	-0.0621	-0.0378	0.2421	-0.1564	0.2199	0.3725	-0.052	0.0432	0.37	0.0176	0.3146	51.5171	-11.1148	35.7827
80	1.5897	-0.1775	-0.4415	2.4865	1.528	4.1257	-0.0738	0.2322	0.0636	-0.3781	-0.0757	0.1497	-0.0439	-0.1362	0.1495	0.1996	-0.0257	0.0014	0.2343	0.014	0.2304	37.8322	-10.2962	45.5126
81	5.7131	3.8343	-1.6223	5.0387	-4.0151	4.884	-0.0839	0.0861	0.2209	0.0412	-0.0429	-0.0629	-0.2584	0.1664	0.1269	0.2598	-0.0063	0.026	0.2098	-0.0584	0.2729	55.2209	-2.6278	51.9544
82	2.5145	0.7668	0.7912	3.5552	2.0288	2.4675	-0.1697	0.3612	-0.0736	-0.5761	-0.0089	0.1058	-0.0073	-0.0197	0.1785	0.2661	-0.0305	0.0123	0.2209	0.0035	0.2211	15.771	-36.4857	47.8858
83	4.6619	-4.586	-4.4672	11.2814	1.4539	9.8434	0.0404	0.1492	-0.0961	-0.1194	0.0408	-0.1416	0.1895	-0.3216	-0.0811	0.2371	0.0203	-0.055	0.1979	0.0165	0.4406	19.0767	-44.906	50.7775
84	0.4818	-0.943	-0.7693	2.0269	1.6136	1.352	-0.0473	0.0745	-0.1159	0.0159	0.0269	0.0356	0.1694	0.0015	0.0204	0.3657	-0.0476	-0.0345	0.3915	-0.0294	0.4369	18.3575	-46.7273	43.9408
85	7.4627	7.1888	2.6808	17.5507	-1.0738	2.2331	-0.3665	0.5753	0.0663	-1.0066	0.3426	-0.0652	0.0905	0.2547	0.0238	0.2853	-0.0549	0.0409	0.3259	-0.0557	0.2652	21.4901	-25.7555	44.4923
86	1.4973	0.6484	0.0452	4.0339	-1.8049	1.9922	-0.0547	0.3735	0.0112	-0.6297	0.126	0.2906	0.3275	0.1094	-0.0714	0.284	-0.0872	-0.0874	0.4134	0.0622	0.2937	16.6274	-33.7615	44.4702
87	15.4071	-2.6893	-7.5871	5.7149	8.4761	14.438	-0.3353	-0.5456	-0.1719	-0.0559	0.3959	0.3557	0.408	0.228	-0.0606	0.3949	-0.1447	-0.1328	0.4322	0.1477	0.6136	8.2539	-48.6925	43.8846
88	8.779	7.0401	-0.2955	6.7901	-2.3698	4.2977	0.2666	-0.3857	-0.2804	-0.0125	-0.2625	-0.0737	0.5171	-0.3046	-0.004	0.3166	0.0463	0.0655	0.3264	-0.0477	0.4819	9.499	-43.1641	54.7487
89	6.4648	-1.0245	-2.2283	4.6561	-0.8391	1.0914	0.0166	0.2402	0.0524	-0.4443	0.0766	0.0981	0.088	-0.1028	-0.0931	0.2933	-0.0242	0.0294	0.2222	0.0047	0.4305	9.3436	-37.2397	50.3372
90	7.5597	-4.6584	-0.957	6.2586	0.7719	0.1878	0.3259	0.1955	0.3039	-0.3443	-0.331	0.4041	-0.1668	-0.1825	0.0051	0.5241	0.0586	-0.0561	0.689	0.0842	0.6402	42.9123	13.7077	42.7706
91	8.5486	-4.6864	-17.2067	35.4838	-4.6726	44.7902	0.3328	-0.1265	0.4792	1.1171	-0.2689	0.1444	-1.5921	0.4581	-0.064	0.6047	-0.179	-0.1017	0.7484	-0.1414	1.142	48.4059	17.96	50.0308
92	13.0088	3.8207	9.6853	1.1681	2.907	7.3225	0.3677	-1.2471	0.0611	-0.0417	-0.258	-0.1181	0.1062	-0.6453	-0.1097	0.8282	-0.2832	-0.0294	1.1286	-0.0047	1.32	45.9545	26.2294	51.7999
93	15.717	-16.0843	-7.392	31.2368	16.3903	10.1512	0.5224	-0.7232	2.2867	1.418	-1.5386	1.0819	0.3437	-1.2102	1.0161	0.9853	-0.2344	0.6363	0.5394	-0.4353	1.4729	35.5016	12.6663	47.4153
94	6.7817	-5.2249	-12.0025	31.7165	6.7104	25.4662	0.1608	0.0422	0.793	-0.6415	0.0228	0.1578	-0.3451	0.3693	-0.1837	0.4245	0.0414	-0.0683	0.4513	0.1961	1.1698	35.4901	4.552	43.972
95	0.8881	6.331	2.6601	60.1227	29.5105	21.5515	-0.3108	-0.3313	0.431	-0.523	-0.657	1.2049	-0.2452	0.6628	0.9679	0.6199	0.1789	-0.2119	0.6042	-0.1328	0.9667	36.9651	19.5221	45.7954
96	3.9329	1.595	0.0983	0.6546	0.0218	0.1073	0.1043	-0.8499	1.2042	0.0389	-0.3795	0.391	-0.2615	0.1266	0.2752	1.1424	-0.3088	-0.0001	0.9451	0.2314	1.6017	45.8696	28.0435	42.1423
97	3.8124	2.9701	-2.3266	2.6859	-0.067	11.5338	0.1498	0.2138	0.3696	-0.1226	-0.0029	0.2456	-1.7193	-0.1019	-0.1469	0.8477	0.1658	0.168	0.559	0.3889	1.1279	44.3762	19.6426	38.1971
98	4.33	0.2128	2.0617	3.2293	-0.8907	2.8596	-0.0008	-0.1761	0.2192	0.2361	-0.1833	-0.2532	-0.0515	0.1367	0.184	0.3885	-0.0098	0.0665	0.3621	-0.0284	0.3006	15.967	47.3123	72.9342
99	10.504	-0.3789	-0.377	1.7656	-0.1968	2.6998	0.1117	-0.3933	0.0827	0.1316	-0.0586	-0.202	-0.0773	-0.1048	-0.0531	0.4665	0.019	-0.0094	0.2417	0.0616	0.4417	15.4458	17.7629	66.9824
100	2.7045	2.2981	-0.8122	13.6646	3.147	2.9445	0.1983	0.0287	-0.3917	0.3155	-0.1459	-0.3693	0.201	-0.1098	-0.0525	0.397	0.0248	-0.0705	0.3215	0.0011	0.3823	6.6338	25.6794	68.0032
101	1.8763	2.4182	-0.4072	5.3797	1.2267	4.17	0.0673	-0.0125	0.1338	0.0438	-0.0922	0.2045	-0.2315	0.026	0.0249	0.2552	0.0429	0.0132	0.2626	0.0257	0.3265	16.4602	50.4255	64.1693
102	7.9328	3.2651	-2.1608	4.0486	-1.5864	4.119	-0.0329	-0.0688	-0.7513	0.1545	-0.1316	-0.1566	0.242	-0.0904	0.1646	0.4048	0.0434	0.0174	0.2738	0.0022	0.3168	13.5568	32.922	69.9151
103	3.6041	5.1032	3.6545	7.6708	5.9816	6.2037	0.4916	-0.1848	-0.3098	0.4697	-0.0262	-0.6545	0.1083	0.2654	-0.4654	0.5242	-0.111	0.0661	0.4025	0.0935	0.301	10.7002	35.3687	77.6062
104	2.8751	0.5982	1.1407	2.1225	-1.7313	6.6108	0.1794	-1.1383	0.186	0.2373	-0.1511	0.0087	0.0752	-0.2576	-0.0282	0.5544	0.015	0.0217	0.5451	0.0091	0.4262	16.825	42.3042	83.2083
105	3.5973	-2.1392	-6.1319	8.1702	4.8653	11.0462	0.2054	-0.2685	0.1814	0.3855	-0.151	-0.1465	-0.1841	0.0353	-0.0544	0.4138	-0.139	0.1796	0.6501	-0.0825	0.3712	5.7871	43.8429	74.6263
106	1.1316	1.9518	0.5331	3.4045	1.04	2.9385	-0.0731	-0.0227	-0.0411	-0.0874	-0.0694	0.0244	0.0965	-0.1601	0.1426	0.2279	-0.0006	0.035	0.25	0.036	0.3328	9.0015	26.5558	58.1876
107	1.1252	-1.6383	-0.2406	5.4667	2.2252	2.9497	0.0744	0.0425	-0.0093	0.0396	-0.0484	-0.2365	0.2133	0.0354	-0.026	0.1903	0.0033	0.035	0.2034	0.0259	0.2874	6.1768	26.2505	52.5179
108	2.7739	0.5717	1.1436	6.434	4.6048	3.8786	0.2849	-0.5979	-0.1204	-0.125	-0.3444	-0.0402	-0.0512	-0.2981	0.0596	0.3315	-0.0414	0.0333	0.2734	0.0534	0.2812	4.3587	24.0605	60.5761
109	2.2182	2.1423	1.4774	6.0669	2.5312	2.0632	0.0052	-0.5949	0.3511	0.0221	-0.2024	0.1201	-0.3663	-0.0629	0.1972	0.3372	-0.003	0.0559	0.3615	0.0075	0.2951	10.7975	47.1054	73.1681
110	0.8946	0.637	0.0326	2.0183	-1.7095	3.1648	-0.0352	-0.1966	-0.1987	0.1835	0.0095	-0.242	0.1956	0.206	0.0257	0.2941	0.0446	-0.0001	0.2905	0.0251	0.2914	23.0369	41.7944	68.5741
111	0.4613	-1.4207	-0.0805	4.9837	-0.6181	3.453	0.0218	-0.003	-0.0594	-0.0499	-0.2625	-0.0949	0.186	0.2927	0.2406	0.2433	-0.0184	0	0.2598	0.0303	0.2262	18.315	39.2233	54.7
112	3.1017	-0.378	3.07	1.3665	-0.2972	3.2015	-0.086	-0.2599	0.1697	0.049	-0.0182	0.1658	-0.2118	-0.4096	0.1042	0.241	0.0129	0.0251	0.291	0.0044	0.2503	8.0942	45.3176	56.7057
113	4.0598	5.8732	4.1456	12.6868	3.1527	6.6402	-0.3522	-0.1482	0.4105	-0.1318	-0.024	0.0852	-0.6494	-0.1508	0.3762	0.3164	0.0462	-0.0598	0.2968	0.0117	0.5193	8.4727	56.0368	63.8241
114	6.5863	-2.8918	-0.0467	6.5754	-0.4058	0.6222	-0.194	-1.3762	0.3034	0.0622	0.2076	-0.3873	-0.2877	0.2239	-0.0135	0.4833	-0.0211	-0.0025	0.3932	0.0038	0.2271	-9.2468	37.0764	56.812
115	6.9183	-6.9069	-0.3166	7.9146	-2.4149	9.6423	0.3211	0.4697	0.0091	-0.7003	-0.2216	0.14	0.6013	-0.3358	-0.0995	0.2754	-0.0756	-0.0374	0.3125	0.0154	0.3178	-14.2057	32.8211	42.5851
116	12.2935	7.844	-6.0157	5.155	-3.9887	4.2731	-0.1958	0.4161	0.0233	-0.0845	0.2522	-0.2307	-0.3921	0.1093	-0.0564	0.4792	0.0172	0.0057	0.3872	-0.102	0.4812	-6.5644	49.6836	29.219
117	0.7098	0.2122	-1.0731	8.5652	6.4971	9.1296	-0.2113	0.4133	-0.0256	-0.7082	-0.0213	0.1556	-0.2097	0.1772	0.2326	0.4324	-0.0448	-0.0045	0.6516	0.0862	0.4443	8.7878	63.0455	34.8624
118	6.9947	6.1223	-1.2799	8.3532	-5.4131	9.0037	-0.1928	0.2039	-0.001	-0.1443	0.0373	-0.3654	-0.3245	0.3689	0.1556	0.2689	0.0412	0.0019	0.2748	-0.0034	0.3867	1.7293	58.9605	44.3802
119	2.4551	0.3812	1.0055	5.8971	-1.1341	1.2387	-0.0084	0.1968	-0.0614	-0.3125	0.0861	0.1589	0.1169	0.0348	-0.0777	0.2251	-0.0138	0.0301	0.2343	-0.0006	0.2291	-3.998	34.9876	42.6639
120	3.4869	-4.5764	-1.3721	12.6419	4.3858	4.436	0.2249	0.1176	0.0798	-0.5749	-0.2234	0.0144	-0.4522	-0.0255	-0.0015	0.2731	-0.0303	-0.0041	0.3907	0.0325	0.3455	-1.4442	52.1397	40.3294
121	6.4208	-6.1759	7.7864	12.807	-9.4187	10.3102	-0.0779	-0.3792	0.3602	0.1508	-0.3953	0.1047	-0.267	-0.5174	0.4732	0.2512	0.0425	-0.0262	0.4703	-0.0519	0.3778	-10.0343	54.6699	45.1867
122	18.3344	-1.8005	-1.5143	0.4341	0.4144	0.4205	-0.2678	-0.0869	-0.1375	-0.0419	0.0951	0.1877	-0.0091	0.0418	0.1728	0.3689	0.018	-0.0062	0.294	0.0523	0.3199	-16.9593	48.0927	38.0699
123	9.9515	0.1506	-2.7434	0.0849	0.3258	3.0505	-0.2435	-1.0163	0.3166	0.0197	-0.078	0.1519	0.05	-0.3101	0.3215	0.2717	0.054	0.0141	0.3516	-0.0033	0.387	-8.5466	47.1459	51.087
124	2.1849	2.0573	-0.3654	3.3226	-1.6155	1.4035	0.0427	-0.1094	-0.1985	-0.023	-0.2726	-0.2414	-0.1127	0.1982	0.2299	0.2244	-0.0071	-0.0114	0.202	0.0173	0.2957	11.2761	55.4136	45.2144
125	3.6314	0.6568	-1.2163	0.3602	-0.8061	2.149	-0.128	0.0341	0.1185	-0.0821	0.0639	0.0411	-0.0582	-0.1789	0.0641	0.2451	0.0372	-0.0494	0.1594	-0.0041	0.235	14.5927	56.2564	48.5838
126	8.6491	5.7014	0.9233	6.366	0.3162	1.5954	0.0829	0.0037	-0.2984	0.0645	-0.0764	-0.1311	0.0569	-0.1679	-0.0064	0.2204	0.0512	-0.0017	0.1892	0.0193	0.2437	-6.1165	46.1389	48.0484
127	0.6084	0.1319	-0.096	0.756	-1.163	2.8521	-0.0263	0.2284	0.2687	-0.1966	-0.1113	-0.0886	0.1164	0.0721	0.1375	0.3099	0.0222	0.033	0.2279	0.0291	0.2965	-1.3334	37.7278	38.1565
128	1.7081	-0.3163	1.2919	2.6085	-2.332	2.7066	0.0435	0.0586	-0.0709	0.0132	-0.0706	-0.1454	-0.0038	0.0846	0.0271	0.221	0.0128	-0.0157	0.1787	-0.0099	0.2746	5.8171	39.7242	47.3455
129	1.3114	1.9848	0.9909	6.4706	3.094	7.2025	0.0911	-0.4099	-0.2704	0.0491	-0.1684	-0.036	0.2249	-0.4459	0.0774	0.1948	-0.0187	0.0296	0.285	0.1023	0.2568	-10.6217	30.4411	52.4975
130	1.5389	0.2179	0.1899	5.196	-1.5493	0.855	-0.2573	0.2268	0.1595	-0.4888	0.2013	-0.1452	0.1137	-0.0153	0.0561	0.2768	-0.0317	0.0148	0.2424	0.0002	0.2342	29.5877	62.41	50.0699
131	2.2931	0.187	1.3201	1.6744	3.3863	8.3108	-0.2335	-0.1875	0.1726	0.108	0.0419	-0.0044	-0.0879	0.084	0.1917	0.3161	0.0334	-0.0151	0.2324	0.0142	0.4399	25.2225	72.3777	51.3721
132	0.0624	-0.3759	-0.076	5.7352	0.3858	0.0955	0.1293	0.1122	-0.0394	-0.6299	-0.1856	0.2803	-0.164	-0.1345	0.0563	0.4417	0.0813	-0.0225	0.3898	-0.0106	0.4326	26.2785	73.9582	43.6825
133	8.2824	3.2266	-3.5171	12.0799	2.4636	2.864	-0.5847	0.8204	0.0802	-1.0027	0.6422	0.0405	-0.0497	-0.1953	-0.0575	0.318	-0.0939	-0.052	0.3611	0.0546	0.2991	23.7126	54.1764	44.4701
134	4.5412	4.506	-0.7699	7.3956	-0.6282	0.4571	-0.2048	0.4055	0.2127	-0.3437	0.2933	-0.0254	-0.0872	-0.0642	-0.0885	0.2891	-0.0292	-0.0026	0.2952	0.0142	0.3024	27.5477	60.2845	45.453
135	0.748	1.1165	-1.4278	3.3903	-4.7814	8.5695	0.073	-0.0043	0.033	-0.2444	0.2045	-0.2317	-0.2772	0.0085	-0.2774	0.5116	-0.1058	0.1454	0.3369	0.0111	0.558	36.9038	76.1886	45.0306
136	2.621	4.0326	4.9742	6.5412	7.979	10.0895	-0.1929	0.1126	0.0664	-0.4332	-0.0541	-0.1094	-0.8139	-0.0008	0.247	0.4282	-0.0577	-0.1631	0.3002	0.1191	0.4487	34.7706	69.9435	55.8039
137	0.8739	1.2883	2.752	2.2732	4.7568	10.938	0.0725	0.1939	0.0353	-0.1484	0.2535	0.0118	-0.2516	1.0381	-0.326	0.2308	0.0146	0.0158	0.2895	-0.0731	0.294	35.4429	64.7276	49.2
138	15.2614	-10.9947	8.4678	13.7025	-9.395	6.6147	-0.272	-0.2377	0.1132	0.3901	-0.1485	-0.7669	-0.1969	0.1432	0.4205	0.3937	-0.0219	-0.0018	0.3518	-0.0527	0.3393	7.677	4.7344	45.3029
139	5.4108	2.0046	1.4575	11.7282	-5.3559	6.2099	-0.0523	-0.5308	0.1515	0.1986	-0.0572	0.0836	0.0274	-0.2484	0.1095	0.3079	0.0079	0.0267	0.2742	-0.0066	0.3554	-1.4709	17.5608	46.7054
140	8.7745	10.0242	-4.5238	19.9117	3.2616	11.1551	-0.2851	-0.2351	-0.2398	0.6155	0.1358	0.2147	1.0566	0.497	0.1493	0.6307	0.0346	0.0752	0.3422	0.019	0.5347	-4.1576	5.5363	50.8186
141	4.7652	3.4091	-0.7992	13.7524	-6.4505	3.243	0.5242	-0.7385	-0.0189	0.2633	-0.5643	0.0964	0.074	0.0969	0.0401	0.5036	0.0071	0.053	0.3405	-0.0584	0.4063	5.7207	8.1683	51.6163
142	0.9478	1.2587	-0.1908	15.8659	-1.3638	0.5591	0.1685	-0.0628	0.0177	0.3433	-0.0762	-0.3381	-0.0179	-0.0425	-0.0922	0.3187	-0.0027	-0.0023	0.3765	0.0112	0.4425	8.6818	15.3978	46.1823
143	17.1857	-8.2315	1.4128	6.3659	-1.2435	0.9512	-0.3748	0.2254	-0.8956	-0.8078	0.5863	1.1592	0.0514	-0.1908	-0.2115	0.6102	-0.1216	-0.141	0.4682	0.1271	0.736	3.2471	-4.5937	47.2237
144	0.5465	-0.1856	-0.8417	0.8533	0.4544	1.4396	-0.1776	0.5213	-0.2357	-0.0778	-0.137	0.1295	0.1815	-0.7898	0.3145	0.5579	-0.0708	-0.1501	0.5919	-0.1046	0.741	-5.0711	5.2268	41.3795
145	5.0154	-1.0698	-7.4893	1.5063	1.9134	11.422	-0.0653	-0.0775	-0.1008	-0.7793	-0.1716	0.1582	0.1934	0.104	0.2369	1.0253	0.1304	-0.0784	0.4291	-0.0246	0.5365	2.5876	6.1142	39.3842
146	0.8283	0.524	0.0758	4.5088	0.7181	1.2883	-0.2328	-0.4014	-0.2313	0.327	0.1786	-0.2128	-0.1511	0.0845	0.0541	0.5242	0.0589	0.0003	0.5927	0.0329	0.2974	71.8116	11.2517	16.8492
147	0.3272	-2.2059	-3.1653	15.5014	22.1344	31.7433	-0.0134	-0.0441	0.0201	-0.1236	-0.1704	0.0684	-0.3136	0.0438	0.1837	0.462	-0.0657	0.0224	0.7366	0.1855	0.6301	78.9346	-14.5319	12.9107
148	12.5264	-0.0468	0.0686	0.1808	-0.645	2.6524	0.1702	-0.3194	0.1696	0.0561	-0.0542	-0.0336	0.1188	0.4395	-0.116	0.5643	0.0948	0.0154	0.4619	-0.0181	0.6367	72.2761	-19.6715	7.1402
149	14.0235	-2.6514	0.3922	0.5765	-0.0697	0.133	0.1406	-0.9935	-0.5866	-0.0094	0.0547	0.2368	0.1674	-0.1057	-0.1953	0.5062	0.0405	-0.0067	0.3959	0.066	0.5872	63.836	-23.1246	10.2162
150	1.8122	1.146	-0.1481	4.1764	0.3971	1.8918	-0.0746	0.0271	-0.1446	-0.1359	0.1244	0.3565	0.0611	-0.0636	-0.0498	0.2188	0.0557	0.0215	0.4405	0.0891	0.3257	68.2718	3.7644	9.4198
151	4.5777	-2.0403	1.6736	4.7653	-4.0777	5.4813	0.0761	-0.1493	-0.3952	-0.2615	0.0214	-0.2383	0.4098	0.0614	-0.0974	0.2758	-0.0091	-0.0014	0.2651	0.0261	0.3127	76.6995	5.9018	8.5999
152	7.2173	3.9014	-3.0775	4.3782	-1.5937	3.8721	-0.1647	0.0071	-0.8566	0.3504	-0.1177	0.0122	0.3511	-0.2607	0.2825	0.3827	0.0026	0.0379	0.3918	0.0832	0.4314	67.4215	-5.5475	13.1217
153	15.5588	7.6263	7.5856	4.5164	2.3654	7.404	-0.0353	-0.821	0.5248	-0.0963	-0.501	-0.1192	0.2664	0.2675	0.5363	0.4324	0.0202	0.0728	0.5384	0.1002	0.4887	69.1261	-1.1009	21.379
154	0.5628	-0.2466	-0.6014	2.7136	0.6847	1.0649	-0.0839	-0.2527	0.0931	0.6559	-0.3119	0.0915	0.3721	-0.154	0.3958	0.4415	-0.1224	0.2658	0.914	-0.3217	0.7428	65.0839	5.1733	21.7764
155	4.2593	-2.3686	-1.9668	1.4845	1.141	4.1112	-0.4072	0.1796	-0.5538	0.3757	-0.0608	0.4857	0.5779	-0.0249	0.468	0.349	0.0027	0.0182	0.3189	0.0636	0.5588	62.6409	-5.573	1.6281
156	5.7921	-9.7226	3.7234	19.6096	-9.4478	5.6817	-0.1736	-0.2248	0.0231	-0.1512	0.1647	-0.2447	0.413	0.1934	0.0088	0.3098	0.0125	0.0672	0.3867	-0.0194	0.5133	67.7712	-13.099	-2.197
157	0.2658	-0.9057	0.0538	4.9684	1.7964	2.4962	0.0208	-0.0508	-0.1385	0.2296	0.1558	0.0252	0.3075	-0.0112	-0.1766	0.2731	-0.0482	0.0175	0.3369	0.058	0.4843	60.301	-10.6884	0.513
158	0.0696	-0.0311	-0.121	0.0786	0.2089	2.7064	0.0395	-0.1442	0.061	0.1139	0.0266	-0.0783	-0.129	-0.1404	-0.066	0.3629	-0.0589	-0.0321	0.4846	0.0567	0.3526	72.1678	7.1707	19.2499
159	1.2955	-1.1568	2.6568	2.2195	-4.2675	9.7062	0.1456	0.0524	-0.1244	-0.0693	-0.3008	-0.1887	0.4445	0.6556	0.1551	0.2203	-0.0198	-0.0207	0.2351	0.0986	0.3224	77.2329	6.9638	4.7419
160	2.0144	-0.5328	0.7794	3.5108	-1.0613	1.4878	0.0072	0.1148	-0.0564	-0.1322	-0.0043	-0.0905	0.0983	0.0662	-0.0028	0.2659	-0.0283	-0.0224	0.2582	0.0212	0.2431	70.5721	3.9124	-0.9289
161	0.4777	0.3041	0.7735	1.1162	-1.0156	4.8243	-0.1229	-0.1064	0.1635	0.3233	-0.0017	-0.1187	-0.8362	0.0182	0.1246	0.3904	0.0436	-0.1046	0.3478	-0.0751	0.4055	65.4292	19.1934	9.1017
162	5.9179	0.3927	0.4432	3.9275	1.0691	8.4209	-0.213	-0.5624	-0.2078	-0.0064	-0.0301	-0.3389	-1.0052	-0.236	0.243	0.2662	0.0352	-0.0476	0.2309	0.0652	0.3271	45.8062	-1.2051	-4.4482
163	3.1509	4.0059	-0.2325	15.9327	-9.8709	9.2446	-0.1065	0.435	-0.0399	-1.1385	0.3482	0.0539	0.6141	-0.0272	-0.2418	0.401	0.0464	0.0001	0.4409	-0.0178	0.289	41.8611	3.8478	-21.5307
164	10.9279	-1.5386	-2.0044	0.5065	-0.3312	1.8015	0.0286	-0.1938	0.0468	0.008	0.2493	0.2049	0.0464	-0.5656	-0.2779	0.4464	-0.0499	0.0687	0.4409	-0.008	0.3914	57.0817	19.8301	-26.9652
165	18.3141	-6.4516	-2.0892	12.849	5.2796	7.9958	-0.3709	0.4492	-0.585	0.1772	0.6295	-0.0991	0.5772	-0.1062	-0.2587	0.4311	-0.0416	-0.0169	0.2783	-0.0069	0.2287	64.6389	24.6818	-22.3881
166	12.6845	-6.6424	3.3609	6.4813	-4.4669	5.456	-0.1518	0.9485	0.3561	-0.2958	0.064	-0.1494	-0.3243	0.2307	0.0878	0.5383	-0.2432	0.0238	0.5794	0.0822	0.2261	65.2265	30.6813	-16.9328
167	1.1421	1.7882	-0.3082	5.3214	-1.187	1.464	-0.1348	0.1783	-0.1006	-0.2905	0.1618	-0.1348	0.0462	-0.1233	-0.027	0.2005	0.0264	0.0202	0.3206	0.0094	0.2977	53.8995	6.7362	-12.6041
168	3.2991	-1.7173	-2.2724	5.0343	1.2132	2.4282	0.0675	0.1739	-0.07	-0.4667	-0.1093	-0.0049	-0.2646	0.0155	0.0418	0.3043	-0.0116	-0.0296	0.3766	0.0317	0.2662	54.8208	16.0187	-15.9902
169	4.6784	2.529	3.9592	12.3634	-4.8389	9.6796	0.1381	-0.336	0.1695	-0.1991	-0.3291	0.2179	0.1162	-0.4768	0.191	0.3053	0.0887	-0.037	0.3545	-0.0006	0.2389	45.9159	17.9564	-12.1617
170	12.5851	-3.0552	-0.253	1.0962	0.4765	1.128	-0.3244	0.513	0.0889	0.0213	-0.0159	0.1783	-0.1563	0.1306	0.3403	0.3824	-0.0236	0.0115	0.3478	0.0568	0.2719	38.4585	12.5842	-18.8603
171	3.7084	2.6644	-2.4306	2.3671	-1.7687	1.8861	-0.0212	-0.115	-0.1445	-0.0233	-0.1474	0.1235	0.0998	-0.2784	0.1686	0.2715	-0.0085	0.0227	0.5387	-0.0085	0.3807	46.5922	10.7241	-5.9936
172	1.4069	-0.2615	1.7697	3.1325	-0.8626	2.3572	-0.0215	0.0692	-0.0643	-0.1697	0.009	-0.1128	0.0189	0.0534	0.0126	0.1531	0.0007	0.0003	0.1764	0.0127	0.1898	69.1176	17.8353	-8.9536
173	5.5247	2.7226	1.0624	1.9637	0.9372	0.6277	-0.0077	-0.097	-0.0984	-0.0492	-0.0508	0.1787	0.0414	-0.1459	0.0585	0.1833	0.0402	0.0051	0.2182	0.0561	0.2031	58.1477	15.6248	-7.1271
174	2.1746	-1.462	0.6909	1.9221	-2.124	3.2607	0.1699	0.6925	0.0085	-0.1165	-0.3554	-0.1435	-0.1179	0.0886	0.1855	0.3241	-0.0392	0.0148	0.4168	-0.0431	0.3041	49.5456	3.8612	-20.217
175	2.0778	2.4554	-4.7148	3.6248	-5.6223	11.6377	-0.148	0.0519	-0.0908	-0.1404	0.2172	-0.1461	0.5145	0.407	-0.0692	0.3255	0.1047	0.0461	0.4302	-0.0185	0.381	66.2164	-0.7313	-14.4339
176	2.122	1.9527	-1.8782	2.9033	-2.8078	6.4831	0.0799	-0.0252	-0.1778	-0.0066	-0.0551	-0.169	-0.1062	0.1868	-0.0248	0.2391	0.0103	-0.0244	0.2356	-0.0064	0.2828	61.5028	3.7999	-8.4631
177	5.5319	3.6921	-1.5252	5.5787	-0.5618	0.5163	-0.1129	0.3433	-0.3796	-0.1413	0.0389	-0.2429	0.0825	-0.1126	0.0739	0.2351	0.0033	0.0086	0.2858	0.0125	0.3212	45.589	-6.305	-5.4862
178	1.061	2.245	-3.8596	5.1396	-8.7431	14.909	0.052	0.1552	0.0906	-0.2118	0.2627	0.1522	0.2888	-0.4315	-0.3147	0.2888	-0.0328	-0.0049	0.2516	0.0352	0.2322	90.0702	30.9258	-12.3268
179	1.3731	1.0373	0.2516	8.6447	-0.8859	3.7546	-0.0209	-0.0689	-0.0065	-0.0572	0.1395	0.3995	-0.0765	-0.3652	-0.1185	0.1743	-0.008	0.0072	0.2214	0.0652	0.2349	82.3967	24.213	-0.2637
180	9.0132	3.0727	-0.4757	6.8207	0.6491	4.5307	0.1452	0.0335	0.0829	0.0779	-0.0971	0.0831	-0.4426	0.2936	-0.0481	0.2305	0.0084	0.01	0.2049	0.0076	0.2702	83.2636	37.3356	-2.2786
181	0.0949	-0.1511	0.1517	2.6471	-1.2803	0.7652	-0.0865	-0.0396	0.0231	-0.3816	0.3047	0.5718	-0.0148	-0.1337	-0.2182	0.3857	-0.0121	-0.0749	0.2396	0.0361	0.3119	81.8074	30.281	-10.6972
182	3.0422	4.1634	-1.0575	9.305	-0.9983	0.7263	-0.1979	0.2862	0.2007	-0.465	0.2868	0.2306	-0.0114	-0.0696	-0.0889	0.2361	-0.0164	0.0118	0.2722	-0.01	0.2289	82.8718	22.3226	-10.0417
183	2.1396	1.1052	3.4137	7.2733	-4.854	12.1447	-0.1262	-0.147	-0.0199	-0.1467	-0.0741	-0.2982	-0.1677	-0.0153	0.2003	0.3567	-0.0327	0.0837	0.3106	-0.0246	0.3621	92.711	40.7117	-9.5502
184	5.4022	1.9435	-2.6589	2.0012	1.1624	5.0204	0.1271	-0.3071	0.0155	-0.1532	-0.1572	-0.12	-0.4297	0.25	0.0301	0.2773	0.0307	-0.0129	0.3068	0.025	0.3596	91.9001	34.0189	0.8984
185	5.5896	0.3213	-4.3998	4.3568	1.0134	4.7523	0.0131	0.5087	0.086	-0.47	0.1687	-0.3395	-0.1391	-0.3381	-0.1819	0.2457	-0.0417	-0.0248	0.3116	0.0134	0.2952	92.1608	28.3998	-5.1998
186	2.3121	1.3861	0.151	5.276	1.5159	0.6283	-0.023	-0.698	0.2263	-0.011	0.1837	-0.1828	0.0706	0.2723	-0.1607	0.5825	0.0675	0.0273	0.5825	-0.1327	0.7217	57.1832	-21.2896	-14.0975
187	12.9109	8.1717	-2.8021	20.9801	-9.5883	4.6606	-0.2723	-1.1137	-1.4058	-0.7767	0.0428	-0.7169	0.5477	-0.2066	0.2294	0.8223	-0.0124	-0.0968	0.4592	-0.0232	0.9019	51.6959	-30.619	-9.0829
188	4.7827	8.7311	3.7425	29.7574	-4.6054	13.5191	0.9197	-0.8013	0.3985	0.7459	-2.0699	0.7056	1.1042	0.2266	1.1502	0.8169	-0.0692	-0.0164	0.5926	0.0057	0.9314	61.6366	-28.0474	-7.7649
189	5.2081	-5.5718	1.2477	7.527	-2.1282	0.7276	0.221	0.3007	-0.3619	-0.332	-0.1812	0.2478	0.1992	0.0177	-0.0398	0.4938	0.043	0.1666	0.5232	-0.1519	0.6252	65.552	-13.0804	-13.4338
190	0.8264	-4.1019	-1.1729	24.7673	7.1106	2.3554	0.015	-0.2018	-0.3729	-1.1633	0.0533	0.6459	-0.0829	-0.0199	-0.0683	0.8782	0.0247	-0.1429	0.684	0.0601	1.2026	63.4906	-32.4336	-10.8322
191	51.006	-2.4913	3.2495	2.9845	2.312	2.3455	0.5206	3.0201	-0.1209	0.655	-0.2275	-0.246	0.6621	0.1222	-0.2931	0.9872	-0.1076	-0.064	0.6858	-0.0704	1.1406	56.854	-38.6562	-15.8111
192	1.092	2.6463	0.0515	6.5116	0.1246	0.0531	-0.2666	0.1826	-0.4858	-0.7953	0.2385	-0.9148	0.1321	0.0376	0.0281	0.7623	0.1623	-0.2329	0.8705	-0.3495	1.125	49.9858	-27.4416	-18.7099
193	6.8642	5.3876	-1.4386	7.1803	3.8328	8.6532	-0.4256	0.5451	-0.3297	-0.5646	-0.0388	0.0302	-0.252	-0.855	0.4644	0.9865	0.0197	-0.115	0.6771	-0.3145	1.0975	57.8782	-28.6016	-20.6754
194	6.0858	2.168	3.0842	15.9394	-3.1816	2.7777	0.3945	-0.3011	-0.6549	0.7858	0.0984	0.4953	0.0388	-0.1894	-0.4929	0.6443	0.0782	-0.0511	0.7022	0.0607	0.4861	11.271	7.7854	27.7484
195	5.4449	-3.221	1.2483	2.6941	-1.3094	2.876	-0.2457	-0.3093	0.3084	0.7111	0.0797	0.2435	0.3735	-1.0476	0.166	1.0575	-0.4991	0.1653	1.1467	0.1652	0.8361	15.9731	-1.091	62.0753

Refinement TLS group

ID	Refine-ID	Refine TLS-ID	Auth asym-ID	Auth seq-ID
1	X-RAY DIFFRACTION	1	A	34 - 44
2	X-RAY DIFFRACTION	2	A	45 - 57
3	X-RAY DIFFRACTION	3	A	58 - 71
4	X-RAY DIFFRACTION	4	A	72 - 80
5	X-RAY DIFFRACTION	5	A	81 - 95
6	X-RAY DIFFRACTION	6	A	96 - 103
7	X-RAY DIFFRACTION	7	A	104 - 118
8	X-RAY DIFFRACTION	8	A	119 - 124
9	X-RAY DIFFRACTION	9	A	125 - 135
10	X-RAY DIFFRACTION	10	A	136 - 146
11	X-RAY DIFFRACTION	11	A	147 - 154
12	X-RAY DIFFRACTION	12	A	155 - 169
13	X-RAY DIFFRACTION	13	A	170 - 188
14	X-RAY DIFFRACTION	14	A	189 - 202
15	X-RAY DIFFRACTION	15	A	203 - 221
16	X-RAY DIFFRACTION	16	A	222 - 228
17	X-RAY DIFFRACTION	17	B	34 - 42
18	X-RAY DIFFRACTION	18	B	43 - 51
19	X-RAY DIFFRACTION	19	B	52 - 62
20	X-RAY DIFFRACTION	20	B	63 - 74
21	X-RAY DIFFRACTION	21	B	75 - 88
22	X-RAY DIFFRACTION	22	B	89 - 99
23	X-RAY DIFFRACTION	23	B	100 - 111
24	X-RAY DIFFRACTION	24	B	112 - 121
25	X-RAY DIFFRACTION	25	B	122 - 135
26	X-RAY DIFFRACTION	26	B	136 - 148
27	X-RAY DIFFRACTION	27	B	149 - 159
28	X-RAY DIFFRACTION	28	B	160 - 171
29	X-RAY DIFFRACTION	29	B	172 - 184
30	X-RAY DIFFRACTION	30	B	185 - 202
31	X-RAY DIFFRACTION	31	B	203 - 210
32	X-RAY DIFFRACTION	32	B	211 - 221
33	X-RAY DIFFRACTION	33	B	222 - 230
34	X-RAY DIFFRACTION	34	C	81 - 93
35	X-RAY DIFFRACTION	35	C	94 - 102
36	X-RAY DIFFRACTION	36	C	103 - 114
37	X-RAY DIFFRACTION	37	C	115 - 119
38	X-RAY DIFFRACTION	38	C	120 - 132
39	X-RAY DIFFRACTION	39	C	133 - 140
40	X-RAY DIFFRACTION	40	C	141 - 149
41	X-RAY DIFFRACTION	41	C	150 - 159
42	X-RAY DIFFRACTION	42	D	81 - 86
43	X-RAY DIFFRACTION	43	D	87 - 94
44	X-RAY DIFFRACTION	44	D	95 - 100
45	X-RAY DIFFRACTION	45	D	101 - 113
46	X-RAY DIFFRACTION	46	D	114 - 130
47	X-RAY DIFFRACTION	47	D	131 - 142
48	X-RAY DIFFRACTION	48	D	143 - 149
49	X-RAY DIFFRACTION	49	D	150 - 159
50	X-RAY DIFFRACTION	50	E	34 - 58
51	X-RAY DIFFRACTION	51	E	59 - 74
52	X-RAY DIFFRACTION	52	E	75 - 88
53	X-RAY DIFFRACTION	53	E	89 - 100
54	X-RAY DIFFRACTION	54	E	101 - 116
55	X-RAY DIFFRACTION	55	E	117 - 124
56	X-RAY DIFFRACTION	56	E	125 - 129
57	X-RAY DIFFRACTION	57	E	130 - 136
58	X-RAY DIFFRACTION	58	E	137 - 144
59	X-RAY DIFFRACTION	59	E	145 - 153
60	X-RAY DIFFRACTION	60	E	154 - 163
61	X-RAY DIFFRACTION	61	E	164 - 174
62	X-RAY DIFFRACTION	62	E	175 - 189
63	X-RAY DIFFRACTION	63	E	190 - 202
64	X-RAY DIFFRACTION	64	E	203 - 221
65	X-RAY DIFFRACTION	65	E	222 - 228
66	X-RAY DIFFRACTION	66	F	34 - 43
67	X-RAY DIFFRACTION	67	F	44 - 51
68	X-RAY DIFFRACTION	68	F	52 - 61
69	X-RAY DIFFRACTION	69	F	62 - 71
70	X-RAY DIFFRACTION	70	F	72 - 81
71	X-RAY DIFFRACTION	71	F	82 - 88
72	X-RAY DIFFRACTION	72	F	89 - 99
73	X-RAY DIFFRACTION	73	F	100 - 109
74	X-RAY DIFFRACTION	74	F	110 - 122
75	X-RAY DIFFRACTION	75	F	123 - 135
76	X-RAY DIFFRACTION	76	F	136 - 150
77	X-RAY DIFFRACTION	77	F	151 - 161
78	X-RAY DIFFRACTION	78	F	162 - 181
79	X-RAY DIFFRACTION	79	F	182 - 199
80	X-RAY DIFFRACTION	80	F	200 - 221
81	X-RAY DIFFRACTION	81	F	222 - 230
82	X-RAY DIFFRACTION	82	G	80 - 95
83	X-RAY DIFFRACTION	83	G	96 - 102
84	X-RAY DIFFRACTION	84	G	103 - 113
85	X-RAY DIFFRACTION	85	G	114 - 120
86	X-RAY DIFFRACTION	86	G	121 - 132
87	X-RAY DIFFRACTION	87	G	133 - 142
88	X-RAY DIFFRACTION	88	G	143 - 149
89	X-RAY DIFFRACTION	89	G	150 - 159
90	X-RAY DIFFRACTION	90	H	83 - 94
91	X-RAY DIFFRACTION	91	H	95 - 100
92	X-RAY DIFFRACTION	92	H	101 - 111
93	X-RAY DIFFRACTION	93	H	112 - 117
94	X-RAY DIFFRACTION	94	H	118 - 124
95	X-RAY DIFFRACTION	95	H	125 - 131
96	X-RAY DIFFRACTION	96	H	133 - 149
97	X-RAY DIFFRACTION	97	H	150 - 158
98	X-RAY DIFFRACTION	98	I	34 - 54
99	X-RAY DIFFRACTION	99	I	55 - 73
100	X-RAY DIFFRACTION	100	I	74 - 81
101	X-RAY DIFFRACTION	101	I	82 - 96
102	X-RAY DIFFRACTION	102	I	97 - 121
103	X-RAY DIFFRACTION	103	I	122 - 127
104	X-RAY DIFFRACTION	104	I	128 - 135
105	X-RAY DIFFRACTION	105	I	136 - 144
106	X-RAY DIFFRACTION	106	I	145 - 155
107	X-RAY DIFFRACTION	107	I	156 - 164
108	X-RAY DIFFRACTION	108	I	165 - 173
109	X-RAY DIFFRACTION	109	I	174 - 185
110	X-RAY DIFFRACTION	110	I	186 - 199
111	X-RAY DIFFRACTION	111	I	200 - 214
112	X-RAY DIFFRACTION	112	I	215 - 221
113	X-RAY DIFFRACTION	113	I	222 - 228
114	X-RAY DIFFRACTION	114	J	34 - 39
115	X-RAY DIFFRACTION	115	J	40 - 46
116	X-RAY DIFFRACTION	116	J	47 - 58
117	X-RAY DIFFRACTION	117	J	59 - 73
118	X-RAY DIFFRACTION	118	J	74 - 81
119	X-RAY DIFFRACTION	119	J	82 - 100
120	X-RAY DIFFRACTION	120	J	101 - 117
121	X-RAY DIFFRACTION	121	J	118 - 124
122	X-RAY DIFFRACTION	122	J	125 - 137
123	X-RAY DIFFRACTION	123	J	138 - 146
124	X-RAY DIFFRACTION	124	J	147 - 154
125	X-RAY DIFFRACTION	125	J	155 - 169
126	X-RAY DIFFRACTION	126	J	170 - 183
127	X-RAY DIFFRACTION	127	J	184 - 205
128	X-RAY DIFFRACTION	128	J	206 - 221
129	X-RAY DIFFRACTION	129	J	222 - 230
130	X-RAY DIFFRACTION	130	K	81 - 93
131	X-RAY DIFFRACTION	131	K	94 - 103
132	X-RAY DIFFRACTION	132	K	104 - 113
133	X-RAY DIFFRACTION	133	K	114 - 119
134	X-RAY DIFFRACTION	134	K	120 - 132
135	X-RAY DIFFRACTION	135	K	133 - 143
136	X-RAY DIFFRACTION	136	K	144 - 149
137	X-RAY DIFFRACTION	137	K	150 - 160
138	X-RAY DIFFRACTION	138	L	80 - 88
139	X-RAY DIFFRACTION	139	L	89 - 95
140	X-RAY DIFFRACTION	140	L	96 - 104
141	X-RAY DIFFRACTION	141	L	105 - 116
142	X-RAY DIFFRACTION	142	L	117 - 132
143	X-RAY DIFFRACTION	143	L	133 - 141
144	X-RAY DIFFRACTION	144	L	142 - 150
145	X-RAY DIFFRACTION	145	L	151 - 159
146	X-RAY DIFFRACTION	146	M	34 - 52
147	X-RAY DIFFRACTION	147	M	53 - 61
148	X-RAY DIFFRACTION	148	M	62 - 68
149	X-RAY DIFFRACTION	149	M	69 - 74
150	X-RAY DIFFRACTION	150	M	75 - 90
151	X-RAY DIFFRACTION	151	M	91 - 100
152	X-RAY DIFFRACTION	152	M	101 - 121
153	X-RAY DIFFRACTION	153	M	122 - 131
154	X-RAY DIFFRACTION	154	M	132 - 144
155	X-RAY DIFFRACTION	155	M	145 - 150
156	X-RAY DIFFRACTION	156	M	151 - 159
157	X-RAY DIFFRACTION	157	M	160 - 175
158	X-RAY DIFFRACTION	158	M	176 - 190
159	X-RAY DIFFRACTION	159	M	191 - 202
160	X-RAY DIFFRACTION	160	M	203 - 221
161	X-RAY DIFFRACTION	161	M	222 - 229
162	X-RAY DIFFRACTION	162	N	34 - 42
163	X-RAY DIFFRACTION	163	N	43 - 51
164	X-RAY DIFFRACTION	164	N	52 - 61
165	X-RAY DIFFRACTION	165	N	62 - 66
166	X-RAY DIFFRACTION	166	N	67 - 72
167	X-RAY DIFFRACTION	167	N	73 - 98
168	X-RAY DIFFRACTION	168	N	99 - 118
169	X-RAY DIFFRACTION	169	N	119 - 126
170	X-RAY DIFFRACTION	170	N	127 - 136
171	X-RAY DIFFRACTION	171	N	137 - 146
172	X-RAY DIFFRACTION	172	N	147 - 163
173	X-RAY DIFFRACTION	173	N	164 - 181
174	X-RAY DIFFRACTION	174	N	182 - 199
175	X-RAY DIFFRACTION	175	N	200 - 207
176	X-RAY DIFFRACTION	176	N	208 - 221
177	X-RAY DIFFRACTION	177	N	222 - 230
178	X-RAY DIFFRACTION	178	O	81 - 86
179	X-RAY DIFFRACTION	179	O	87 - 95
180	X-RAY DIFFRACTION	180	O	96 - 105
181	X-RAY DIFFRACTION	181	O	106 - 117
182	X-RAY DIFFRACTION	182	O	118 - 132
183	X-RAY DIFFRACTION	183	O	133 - 141
184	X-RAY DIFFRACTION	184	O	142 - 149
185	X-RAY DIFFRACTION	185	O	150 - 160
186	X-RAY DIFFRACTION	186	P	84 - 95
187	X-RAY DIFFRACTION	187	P	96 - 104
188	X-RAY DIFFRACTION	188	P	105 - 116
189	X-RAY DIFFRACTION	189	P	117 - 125
190	X-RAY DIFFRACTION	190	P	126 - 134
191	X-RAY DIFFRACTION	191	P	135 - 144
192	X-RAY DIFFRACTION	192	P	145 - 150
193	X-RAY DIFFRACTION	193	P	151 - 158
194	X-RAY DIFFRACTION	194	R	1 - 5
195	X-RAY DIFFRACTION	195	S	1 - 5