Entry Database : PDB / ID : 3mw2 Structure visualization Downloads & linksTitle Crystal structure of beta-neurexin 1 with the splice insert 4 ComponentsNeurexin-1-alpha Details Keywords CELL ADHESION / NEUREXIN / LNS domain / CALCIUM-binding / GLYCOPROTEINFunction / homology Function and homology informationFunction Domain/homology Component
regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission / trans-synaptic signaling, modulating synaptic transmission / regulation of postsynaptic specialization assembly / gephyrin clustering involved in postsynaptic density assembly / Neurexins and neuroligins / neuroligin clustering involved in postsynaptic membrane assembly / postsynaptic density protein 95 clustering / postsynaptic membrane assembly / neuroligin family protein binding / positive regulation of synapse maturation ... regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission / trans-synaptic signaling, modulating synaptic transmission / regulation of postsynaptic specialization assembly / gephyrin clustering involved in postsynaptic density assembly / Neurexins and neuroligins / neuroligin clustering involved in postsynaptic membrane assembly / postsynaptic density protein 95 clustering / postsynaptic membrane assembly / neuroligin family protein binding / positive regulation of synapse maturation / regulation of postsynaptic density assembly / synaptic membrane adhesion / regulation of grooming behavior / presynapse assembly / regulation of synaptic vesicle cycle / neurotransmitter secretion / acetylcholine receptor binding / positive regulation of synapse assembly / adult behavior / positive regulation of excitatory postsynaptic potential / neuromuscular process controlling balance / regulation of presynapse assembly / endocytic vesicle / calcium channel regulator activity / GABA-ergic synapse / prepulse inhibition / presynaptic active zone membrane / cell adhesion molecule binding / synapse assembly / cellular response to calcium ion / positive regulation of synaptic transmission, glutamatergic / learning / cell projection / Schaffer collateral - CA1 synapse / transmembrane signaling receptor activity / presynaptic membrane / chemical synaptic transmission / nuclear membrane / vesicle / signaling receptor binding / neuronal cell body / glutamatergic synapse / calcium ion binding / protein-containing complex binding / nucleolus / cell surface / signal transduction / endoplasmic reticulum / protein-containing complex / plasma membrane Similarity search - Function : / Neurexin/syndecan/glycophorin C / putative band 4.1 homologues' binding motif / Laminin G domain / Laminin G domain profile. / Laminin G domain / Laminin G domain / EGF-like domain / EGF-type aspartate/asparagine hydroxylation site / Aspartic acid and asparagine hydroxylation site. ... : / Neurexin/syndecan/glycophorin C / putative band 4.1 homologues' binding motif / Laminin G domain / Laminin G domain profile. / Laminin G domain / Laminin G domain / EGF-like domain / EGF-type aspartate/asparagine hydroxylation site / Aspartic acid and asparagine hydroxylation site. / Epidermal growth factor-like domain. / Jelly Rolls - #200 / EGF-like domain profile. / EGF-like domain / Concanavalin A-like lectin/glucanase domain superfamily / Jelly Rolls / Sandwich / Mainly Beta Similarity search - Domain/homologyBiological species Mus musculus (house mouse)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 2.69 Å DetailsAuthors Jin, X. / Shapiro, L. CitationJournal : Neuron / Year : 2010Title : Splice Form Dependence of beta-Neurexin/Neuroligin Binding Interactions.Authors : Koehnke, J. / Katsamba, P.S. / Ahlsen, G. / Bahna, F. / Vendome, J. / Honig, B. / Shapiro, L. / Jin, X. History Deposition May 5, 2010 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Jul 28, 2010 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Advisory / Version format complianceRevision 1.2 Nov 8, 2017 Group : Refinement description / Category : software / Item : _software.nameRevision 2.0 Jul 29, 2020 Group : Atomic model / Data collection ... Atomic model / Data collection / Database references / Derived calculations / Structure summary Category : atom_site / chem_comp ... atom_site / chem_comp / entity / pdbx_branch_scheme / pdbx_chem_comp_identifier / pdbx_entity_branch / pdbx_entity_branch_descriptor / pdbx_entity_branch_link / pdbx_entity_branch_list / pdbx_entity_nonpoly / pdbx_nonpoly_scheme / pdbx_struct_assembly_gen / struct_asym / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item : _atom_site.B_iso_or_equiv / _atom_site.Cartn_x ... _atom_site.B_iso_or_equiv / _atom_site.Cartn_x / _atom_site.Cartn_y / _atom_site.Cartn_z / _atom_site.auth_asym_id / _atom_site.auth_atom_id / _atom_site.auth_comp_id / _atom_site.auth_seq_id / _atom_site.label_asym_id / _atom_site.label_atom_id / _atom_site.label_comp_id / _atom_site.label_entity_id / _atom_site.type_symbol / _chem_comp.name / _chem_comp.type / _pdbx_struct_assembly_gen.asym_id_list / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_ref_seq_dif.details Description : Carbohydrate remediation / Provider : repository / Type : RemediationRevision 2.1 Sep 6, 2023 Group : Data collection / Database references ... Data collection / Database references / Refinement description / Structure summary Category : chem_comp / chem_comp_atom ... chem_comp / chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item : _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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