+Open data
-Basic information
Entry | Database: PDB / ID: 3kl8 | ||||||
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Title | CaMKIINtide Inhibitor Complex | ||||||
Components |
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Keywords | TRANSFERASE/ TRANSFERASE INHIBITOR / CaMKII / CaMKIINtide / ATP-binding / Kinase / Nucleotide-binding / Serine/threonine-protein kinase / Cell junction / Cell membrane / Membrane / Postsynaptic cell membrane / Protein kinase inhibitor / Synapse / Synaptosome / TRANSFERASE- TRANSFERASE INHIBITOR complex | ||||||
Function / homology | Function and homology information medium-term memory / Unblocking of NMDA receptors, glutamate binding and activation / Ion transport by P-type ATPases / Ion homeostasis / Ca2+ pathway / HSF1-dependent transactivation / calcium-dependent protein kinase inhibitor activity / negative regulation of cyclin-dependent protein kinase activity / serotonin biosynthetic process / Ca2+/calmodulin-dependent protein kinase ...medium-term memory / Unblocking of NMDA receptors, glutamate binding and activation / Ion transport by P-type ATPases / Ion homeostasis / Ca2+ pathway / HSF1-dependent transactivation / calcium-dependent protein kinase inhibitor activity / negative regulation of cyclin-dependent protein kinase activity / serotonin biosynthetic process / Ca2+/calmodulin-dependent protein kinase / positive regulation of systemic arterial blood pressure / calmodulin-dependent protein kinase activity / protein kinase inhibitor activity / positive regulation of insulin secretion involved in cellular response to glucose stimulus / negative regulation of cell cycle / calcium ion homeostasis / axon cytoplasm / negative regulation of proteolysis / peptidyl-threonine phosphorylation / negative regulation of protein kinase activity / negative regulation of ERK1 and ERK2 cascade / MAPK cascade / chemical synaptic transmission / perikaryon / peptidyl-serine phosphorylation / transmembrane transporter binding / postsynaptic density / calmodulin binding / neuron projection / negative regulation of cell population proliferation / phosphorylation / protein phosphorylation / protein serine kinase activity / dendrite / neuronal cell body / synapse / positive regulation of gene expression / protein kinase binding / ATP binding / identical protein binding / metal ion binding / cytoplasm Similarity search - Function | ||||||
Biological species | Caenorhabditis elegans (invertebrata) Rattus norvegicus (Norway rat) | ||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 3.372 Å | ||||||
Authors | Kuriyan, J. / Chao, L.H. / Pellicena, P. / Deindl, S. / Barclay, L.A. / Schulman, H. | ||||||
Citation | Journal: Nat.Struct.Mol.Biol. / Year: 2010 Title: Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation. Authors: Chao, L.H. / Pellicena, P. / Deindl, S. / Barclay, L.A. / Schulman, H. / Kuriyan, J. | ||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3kl8.cif.gz | 302.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb3kl8.ent.gz | 248.5 KB | Display | PDB format |
PDBx/mmJSON format | 3kl8.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/kl/3kl8 ftp://data.pdbj.org/pub/pdb/validation_reports/kl/3kl8 | HTTPS FTP |
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-Related structure data
-Links
-Assembly
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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