+Open data
-Basic information
Entry | Database: PDB / ID: 3k72 | |||||||||
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Title | Structure of integrin alphaX beta2 | |||||||||
Components |
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Keywords | CELL ADHESION / integrin / cell receptor / Pyrrolidone carboxylic acid | |||||||||
Function / homology | Function and homology information positive regulation of endothelial tube morphogenesis / integrin alphaX-beta2 complex / integrin alphaM-beta2 complex / positive regulation of prostaglandin-E synthase activity / positive regulation of neutrophil degranulation / integrin alphaL-beta2 complex / ICAM-3 receptor activity / positive regulation of myelination / complement component C3b binding / neutrophil migration ...positive regulation of endothelial tube morphogenesis / integrin alphaX-beta2 complex / integrin alphaM-beta2 complex / positive regulation of prostaglandin-E synthase activity / positive regulation of neutrophil degranulation / integrin alphaL-beta2 complex / ICAM-3 receptor activity / positive regulation of myelination / complement component C3b binding / neutrophil migration / Toll Like Receptor 4 (TLR4) Cascade / negative regulation of dopamine metabolic process / cell-cell adhesion via plasma-membrane adhesion molecules / heterotypic cell-cell adhesion / integrin complex / positive regulation of leukocyte adhesion to vascular endothelial cell / cell adhesion mediated by integrin / phagocytosis, engulfment / leukocyte cell-cell adhesion / receptor clustering / amyloid-beta clearance / endodermal cell differentiation / plasma membrane raft / tertiary granule membrane / ficolin-1-rich granule membrane / cellular response to low-density lipoprotein particle stimulus / positive regulation of protein targeting to membrane / ECM proteoglycans / Integrin cell surface interactions / specific granule membrane / regulation of peptidyl-tyrosine phosphorylation / heat shock protein binding / receptor-mediated endocytosis / cell adhesion molecule binding / cell-matrix adhesion / neutrophil chemotaxis / secretory granule membrane / positive regulation of superoxide anion generation / integrin-mediated signaling pathway / Cell surface interactions at the vascular wall / microglial cell activation / animal organ morphogenesis / receptor internalization / cell-cell adhesion / receptor tyrosine kinase binding / positive regulation of angiogenesis / extracellular vesicle / Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell / integrin binding / cell-cell signaling / signaling receptor activity / amyloid-beta binding / regulation of cell shape / defense response to virus / Interleukin-4 and Interleukin-13 signaling / receptor complex / cell adhesion / positive regulation of cell migration / inflammatory response / external side of plasma membrane / focal adhesion / apoptotic process / positive regulation of cell population proliferation / Neutrophil degranulation / positive regulation of gene expression / protein kinase binding / cell surface / extracellular exosome / membrane / metal ion binding / plasma membrane Similarity search - Function | |||||||||
Biological species | Homo sapiens (human) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MAD / Resolution: 3.7 Å | |||||||||
Authors | Xie, C. / Zhu, J. / Chen, X. / Mi, L. / Nishida, N. / Springer, T.A. | |||||||||
Citation | Journal: Embo J. / Year: 2010 Title: Structure of an integrin with an alphaI domain, complement receptor type 4. Authors: Xie, C. / Zhu, J. / Chen, X. / Mi, L. / Nishida, N. / Springer, T.A. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 3k72.cif.gz | 1.2 MB | Display | PDBx/mmCIF format |
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PDB format | pdb3k72.ent.gz | 1 MB | Display | PDB format |
PDBx/mmJSON format | 3k72.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/k7/3k72 ftp://data.pdbj.org/pub/pdb/validation_reports/k7/3k72 | HTTPS FTP |
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-Related structure data
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments:
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