登録情報 | データベース: PDB / ID: 3inb |
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タイトル | Structure of the measles virus hemagglutinin bound to the CD46 receptor |
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要素 | - Hemagglutinin glycoprotein
- Membrane cofactor protein
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キーワード | VIRAL PROTEIN/IMMUNE SYSTEM / MEASLES / BETA PROPELLER / ENVELOPE PROTEIN / HEMAGGLUTININ / VIRAL PROTEIN. MEMBRANE COFACTOR PROTEIN / MCP / CD46 / VIRUS RECEPTOR COMPLEX / SCR / COMPLEMENT CONTROL PROTEIN / IMMUNE SYSTEM COMPLEX / Membrane / Transmembrane / Virion / Cell membrane / Glycoprotein / Host-virus interaction / Signal-anchor / Complement pathway / Disease mutation / Disulfide bond / Fertilization / Immune response / Innate immunity / Phosphoprotein / Sushi / VIRAL PROTEIN / IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX |
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機能・相同性 | 機能・相同性情報
sequestering of extracellular ligand from receptor / inner acrosomal membrane / negative regulation of complement activation, classical pathway / positive regulation of transforming growth factor beta production / T cell mediated immunity / regulation of Notch signaling pathway / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / positive regulation of interleukin-10 production / complement activation, classical pathway ...sequestering of extracellular ligand from receptor / inner acrosomal membrane / negative regulation of complement activation, classical pathway / positive regulation of transforming growth factor beta production / T cell mediated immunity / regulation of Notch signaling pathway / positive regulation of memory T cell differentiation / positive regulation of regulatory T cell differentiation / positive regulation of interleukin-10 production / complement activation, classical pathway / single fertilization / positive regulation of T cell proliferation / Regulation of Complement cascade / signaling receptor activity / virus receptor activity / adaptive immune response / host cell surface receptor binding / cadherin binding / receptor ligand activity / negative regulation of gene expression / innate immune response / focal adhesion / viral envelope / positive regulation of gene expression / symbiont entry into host cell / virion attachment to host cell / host cell plasma membrane / virion membrane / cell surface / extracellular space / extracellular exosome / plasma membrane類似検索 - 分子機能 Membrane cofactor protein CD46 / : / : / Haemagglutinin/haemagglutinin-neuraminidase, paramyxovirus / Haemagglutinin-neuraminidase / Complement Module, domain 1 / Complement Module; domain 1 / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain ...Membrane cofactor protein CD46 / : / : / Haemagglutinin/haemagglutinin-neuraminidase, paramyxovirus / Haemagglutinin-neuraminidase / Complement Module, domain 1 / Complement Module; domain 1 / Sushi repeat (SCR repeat) / Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR) / Sushi/SCR/CCP domain / Sushi/CCP/SCR domain profile. / Sushi/SCR/CCP superfamily / Neuraminidase - #10 / Sialidase superfamily / 6 Propeller / Neuraminidase / Ribbon / Mainly Beta類似検索 - ドメイン・相同性 Hemagglutinin glycoprotein / Membrane cofactor protein類似検索 - 構成要素 |
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生物種 | Measles virus strain Edmonston (ウイルス)
Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 3.1 Å |
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データ登録者 | Santiago, C. / Celma, M.L. / Stehle, T. / Casasnovas, J.M. |
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引用 | ジャーナル: Nat.Struct.Mol.Biol. / 年: 2010 タイトル: Structure of the measles virus hemagglutinin bound to the CD46 receptor 著者: Santiago, C. / Celma, M.L. / Stehle, T. / Casasnovas, J.M. |
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履歴 | 登録 | 2009年8月12日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年12月22日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Non-polymer description / Version format compliance |
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改定 1.2 | 2020年7月29日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Structure summary カテゴリ: chem_comp / diffrn_source ...chem_comp / diffrn_source / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_ref_seq_dif / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _diffrn_source.pdbx_synchrotron_site / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.pdbx_role / _struct_ref_seq_dif.details 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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改定 1.3 | 2021年10月13日 | Group: Database references / Structure summary / カテゴリ: chem_comp / database_2 / struct_ref_seq_dif Item: _chem_comp.pdbx_synonyms / _database_2.pdbx_DOI ..._chem_comp.pdbx_synonyms / _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
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改定 1.4 | 2023年9月6日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
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改定 1.5 | 2024年11月20日 | Group: Structure summary カテゴリ: pdbx_entry_details / pdbx_modification_feature |
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