登録情報 | データベース: PDB / ID: 3i8z |
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タイトル | Crystal structure of human chromobox homolog 4 (CBX4) |
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要素 | E3 SUMO-protein ligase CBX4 |
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キーワード | TRANSCRIPTION / chromobox homolog 4 / CBX4 / Structural Genomics / Structural Genomics Consortium / SGC / Alternative splicing / Chromatin regulator / Isopeptide bond / Nucleus / Phosphoprotein / Repressor / Transcription regulation / Ubl conjugation / Ubl conjugation pathway |
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機能・相同性 | 機能・相同性情報
PRC1 complex / SUMO ligase activity / PcG protein complex / SUMO binding / SUMOylation of DNA methylation proteins / SUMOylation of RNA binding proteins / 転移酵素; アシル基を移すもの; アミノアシル基を移すもの / SUMO transferase activity / SUMOylation of chromatin organization proteins / RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known ...PRC1 complex / SUMO ligase activity / PcG protein complex / SUMO binding / SUMOylation of DNA methylation proteins / SUMOylation of RNA binding proteins / 転移酵素; アシル基を移すもの; アミノアシル基を移すもの / SUMO transferase activity / SUMOylation of chromatin organization proteins / RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known / protein sumoylation / SUMOylation of DNA damage response and repair proteins / Regulation of PTEN gene transcription / methylated histone binding / SUMOylation of transcription cofactors / phosphoprotein binding / transcription corepressor activity / chromatin organization / Oxidative Stress Induced Senescence / transcription cis-regulatory region binding / single-stranded RNA binding / nuclear body / nuclear speck / negative regulation of DNA-templated transcription / chromatin binding / negative regulation of apoptotic process / enzyme binding / negative regulation of transcription by RNA polymerase II / nucleoplasm / nucleus類似検索 - 分子機能 E3 SUMO-protein ligase CBX4 / CBX family C-terminal motif / CBX family C-terminal motif / Chromo domain subgroup / Chromo domain, conserved site / Chromo domain signature. / Chromo domain / Chromo (CHRromatin Organisation MOdifier) domain / Chromo and chromo shadow domain profile. / OB fold (Dihydrolipoamide Acetyltransferase, E2P) - #40 ...E3 SUMO-protein ligase CBX4 / CBX family C-terminal motif / CBX family C-terminal motif / Chromo domain subgroup / Chromo domain, conserved site / Chromo domain signature. / Chromo domain / Chromo (CHRromatin Organisation MOdifier) domain / Chromo and chromo shadow domain profile. / OB fold (Dihydrolipoamide Acetyltransferase, E2P) - #40 / Chromo/chromo shadow domain / Chromatin organization modifier domain / Chromo-like domain superfamily / OB fold (Dihydrolipoamide Acetyltransferase, E2P) / Beta Barrel / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 1.51 Å |
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データ登録者 | Amaya, M.F. / Zhihong, L. / Loppnau, P. / Kozieradzki, I. / Edwards, A.M. / Arrowsmith, C.H. / Weigelt, J. / Bountra, C. / Bochkarev, A. / Min, J. ...Amaya, M.F. / Zhihong, L. / Loppnau, P. / Kozieradzki, I. / Edwards, A.M. / Arrowsmith, C.H. / Weigelt, J. / Bountra, C. / Bochkarev, A. / Min, J. / Ouyang, H. / Structural Genomics Consortium (SGC) |
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引用 | ジャーナル: To be Published タイトル: Crystal structure of human chromobox homolog 4 (CBX4) 著者: Zhihong, L. / Amaya, M.F. / Loppnau, P. / Kozieradzki, I. / Edwards, A.M. / Arrowsmith, C.H. / Weigelt, J. / Bountra, C. / Bochkarev, A. / Min, J. / Ouyang, H. / Structural Genomics Consortium (SGC) |
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履歴 | 登録 | 2009年7月10日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年8月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2017年11月1日 | Group: Refinement description / カテゴリ: software |
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改定 1.3 | 2023年9月6日 | Group: Data collection / Database references / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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