Entry Database : PDB / ID : 3hpq Structure visualization Downloads & linksTitle Crystal structure of wild-type adenylate kinase from E. coli, in complex with Ap5A ComponentsAdenylate kinase Details Keywords TRANSFERASE / Enzyme Inhibitor Complex / ATP-binding / Kinase / Nucleotide biosynthesis / Nucleotide-bindingFunction / homology Function and homology informationFunction Domain/homology Component
purine ribonucleotide interconversion / ADP biosynthetic process / nucleoside monophosphate metabolic process / CDP biosynthetic process / nucleoside diphosphate metabolic process / (d)CMP kinase activity / UMP kinase activity / adenylate kinase / adenylate kinase activity / AMP salvage ... purine ribonucleotide interconversion / ADP biosynthetic process / nucleoside monophosphate metabolic process / CDP biosynthetic process / nucleoside diphosphate metabolic process / (d)CMP kinase activity / UMP kinase activity / adenylate kinase / adenylate kinase activity / AMP salvage / UDP biosynthetic process / nucleoside diphosphate kinase activity / AMP binding / phosphorylation / magnesium ion binding / ATP binding / cytoplasm / cytosol Similarity search - Function Adenylate kinase, active site lid domain / Adenylate kinase, active site lid / Adenylate kinase subfamily / Adenylate kinase / Adenylate kinase, conserved site / Adenylate kinase signature. / Adenylate kinase/UMP-CMP kinase / P-loop containing nucleotide triphosphate hydrolases / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase ... Adenylate kinase, active site lid domain / Adenylate kinase, active site lid / Adenylate kinase subfamily / Adenylate kinase / Adenylate kinase, conserved site / Adenylate kinase signature. / Adenylate kinase/UMP-CMP kinase / P-loop containing nucleotide triphosphate hydrolases / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species Escherichia coli (E. coli)Method X-RAY DIFFRACTION / MOLECULAR REPLACEMENT / Resolution : 2 Å DetailsAuthors Hilser, V.J. / Travis, T.P. / Bolen, D.W. CitationJournal : Proc.Natl.Acad.Sci.USA / Year : 2009Title : Rational modulation of conformational fluctuations in adenylate kinase reveals a local unfolding mechanism for allostery and functional adaptation in proteins.Authors : Schrank, T.P. / Bolen, D.W. / Hilser, V.J. History Deposition Jun 4, 2009 Deposition site : RCSB / Processing site : RCSBRevision 1.0 Nov 3, 2009 Provider : repository / Type : Initial releaseRevision 1.1 Jul 13, 2011 Group : Source and taxonomy / Version format complianceRevision 1.2 Sep 6, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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