登録情報 | データベース: PDB / ID: 3fm8 |
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タイトル | Crystal structure of full length centaurin alpha-1 bound with the FHA domain of KIF13B (CAPRI target) |
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要素 | - Centaurin-alpha-1
- Kinesin-like protein KIF13B
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キーワード | TRANSPORT PROTEIN/HYDROLASE ACTIVATOR / kinesin / GAP / GTPase activation / Structural Genomics Consortium / SGC / ATP-binding / Cytoskeleton / Microtubule / Motor protein / Nucleotide-binding / Phosphoprotein / Metal-binding / Nucleus / Zinc-finger / METAL BINDING PROTEIN / TRANSPORT PROTEIN-HYDROLASE ACTIVATOR COMPLEX |
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機能・相同性 | 機能・相同性情報
inositol 1,3,4,5 tetrakisphosphate binding / cytoskeleton-dependent intracellular transport / Kinesins / COPI-dependent Golgi-to-ER retrograde traffic / microtubule motor activity / kinesin complex / phosphatidylinositol bisphosphate binding / regulation of axonogenesis / regulation of GTPase activity / microtubule-based movement ...inositol 1,3,4,5 tetrakisphosphate binding / cytoskeleton-dependent intracellular transport / Kinesins / COPI-dependent Golgi-to-ER retrograde traffic / microtubule motor activity / kinesin complex / phosphatidylinositol bisphosphate binding / regulation of axonogenesis / regulation of GTPase activity / microtubule-based movement / phosphatidylinositol-3,4,5-trisphosphate binding / protein targeting / Nuclear signaling by ERBB4 / 14-3-3 protein binding / T cell activation / GTPase activator activity / microtubule binding / microtubule / cell surface receptor signaling pathway / axon / intracellular membrane-bounded organelle / protein kinase binding / signal transduction / ATP hydrolysis activity / ATP binding / nucleus / metal ion binding / plasma membrane / cytosol / cytoplasm類似検索 - 分子機能 ADAP, PH domain 1 / ADAP, PH domain 2 / Arf GTPase activating protein / Kinesin-like KIF1-type / Kinesin protein 1B / Arf GTPase activating protein / Kinesin-like / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / Kinesin protein ...ADAP, PH domain 1 / ADAP, PH domain 2 / Arf GTPase activating protein / Kinesin-like KIF1-type / Kinesin protein 1B / Arf GTPase activating protein / Kinesin-like / ArfGAP domain superfamily / Putative GTPase activating protein for Arf / Kinesin protein / ARF GTPase-activating proteins domain profile. / Putative GTP-ase activating proteins for the small GTPase, ARF / CAP-Gly domain signature. / CAP Gly-rich domain / CAP Gly-rich domain superfamily / ARFGAP/RecO-like zinc finger / CAP-Gly domain / CAP-Gly domain profile. / CAP_GLY / Tumour Suppressor Smad4 - #20 / Kinesin-associated / Kinesin-associated / Annexin V; domain 1 / Tumour Suppressor Smad4 / FHA domain / Forkhead-associated (FHA) domain / Kinesin motor domain signature. / Kinesin motor domain, conserved site / Kinesin motor domain / Kinesin motor domain profile. / Kinesin motor, catalytic domain. ATPase. / Kinesin motor domain / SMAD/FHA domain superfamily / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / Kinesin motor domain superfamily / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / PH-like domain superfamily / Roll / Sandwich / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Beta / Mainly Alpha類似検索 - ドメイン・相同性 Arf-GAP with dual PH domain-containing protein 1 / Kinesin-like protein KIF13B類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.3 Å |
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データ登録者 | Shen, L. / Tong, Y. / Tempel, W. / MacKenzie, F. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Weigelt, J. / Bochkarev, A. / Park, H. / Structural Genomics Consortium (SGC) |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2010 タイトル: Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1. 著者: Tong, Y. / Tempel, W. / Wang, H. / Yamada, K. / Shen, L. / Senisterra, G.A. / MacKenzie, F. / Chishti, A.H. / Park, H.W. |
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履歴 | 登録 | 2008年12月19日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2009年8月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2013年9月25日 | Group: Derived calculations |
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改定 1.3 | 2017年11月1日 | Group: Refinement description / カテゴリ: software |
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改定 1.4 | 2024年2月21日 | Group: Data collection / Database references / Derived calculations カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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改定 1.5 | 2024年4月3日 | Group: Refinement description / カテゴリ: pdbx_initial_refinement_model |
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