登録情報 | データベース: PDB / ID: 3ee6 |
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タイトル | Crystal Structure Analysis of Tripeptidyl peptidase -I |
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要素 | Tripeptidyl-peptidase 1 |
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キーワード | HYDROLASE / tripepetidyl peptidase -I / Disease mutation / Epilepsy / Glycoprotein / Lysosome / Neuronal ceroid lipofuscinosis / Protease / Serine protease / Zymogen |
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機能・相同性 | 機能・相同性情報
tripeptidyl-peptidase I / sulfatide binding / lysophosphatidic acid binding / lysosomal protein catabolic process / tripeptidyl-peptidase activity / XBP1(S) activates chaperone genes / protein localization to chromosome, telomeric region / lysosome organization / peptide catabolic process / neuromuscular process controlling balance ...tripeptidyl-peptidase I / sulfatide binding / lysophosphatidic acid binding / lysosomal protein catabolic process / tripeptidyl-peptidase activity / XBP1(S) activates chaperone genes / protein localization to chromosome, telomeric region / lysosome organization / peptide catabolic process / neuromuscular process controlling balance / epithelial cell differentiation / bone resorption / serine-type peptidase activity / lysosomal lumen / peptide binding / central nervous system development / lipid metabolic process / protein catabolic process / recycling endosome / melanosome / nervous system development / peptidase activity / endopeptidase activity / lysosome / membrane raft / serine-type endopeptidase activity / Golgi apparatus / proteolysis / extracellular exosome / metal ion binding類似検索 - 分子機能 Peptidase S53, activation domain / Sedolisin domain / Pro-kumamolisin, activation domain / Sedolisin domain profile. / Pro-kumamolisin, activation domain / Peptidase S8/S53 domain / Peptidase S8/S53 domain superfamily / Subtilase family / Peptidase S8/S53 domain / Rossmann fold ...Peptidase S53, activation domain / Sedolisin domain / Pro-kumamolisin, activation domain / Sedolisin domain profile. / Pro-kumamolisin, activation domain / Peptidase S8/S53 domain / Peptidase S8/S53 domain superfamily / Subtilase family / Peptidase S8/S53 domain / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.35 Å |
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データ登録者 | Pal, A. / Kraetzner, R. / Grapp, M. / Gruene, T. / Schreiber, K. / Granborg, M. / Urlaub, H. / Asif, A.R. / Becker, S. / Gartner, J. ...Pal, A. / Kraetzner, R. / Grapp, M. / Gruene, T. / Schreiber, K. / Granborg, M. / Urlaub, H. / Asif, A.R. / Becker, S. / Gartner, J. / Sheldrick, G.M. / Steinfeld, R. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2009 タイトル: Structure of tripeptidyl-peptidase I provides insight into the molecular basis of late infantile neuronal ceroid lipofuscinosis 著者: Pal, A. / Kraetzner, R. / Gruene, T. / Grapp, M. / Schreiber, K. / Gronborg, M. / Urlaub, H. / Becker, S. / Asif, A.R. / Gartner, J. / Sheldrick, G.M. / Steinfeld, R. |
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履歴 | 登録 | 2008年9月4日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2008年11月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Advisory / Version format compliance |
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改定 1.2 | 2018年6月20日 | Group: Data collection / Source and taxonomy / カテゴリ: entity_src_gen Item: _entity_src_gen.pdbx_host_org_cell_line / _entity_src_gen.pdbx_host_org_strain |
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改定 1.3 | 2020年7月29日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Structure summary カテゴリ: chem_comp / entity ...chem_comp / entity / pdbx_chem_comp_identifier / pdbx_entity_nonpoly / struct_conn / struct_conn_type / struct_ref_seq_dif / struct_site / struct_site_gen Item: _chem_comp.name / _chem_comp.type ..._chem_comp.name / _chem_comp.type / _entity.pdbx_description / _pdbx_entity_nonpoly.name / _struct_conn.conn_type_id / _struct_conn.id / _struct_conn.pdbx_dist_value / _struct_conn.pdbx_leaving_atom_flag / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_conn_type.id / _struct_ref_seq_dif.details 解説: Carbohydrate remediation / Provider: repository / タイプ: Remediation |
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