登録情報 データベース : PDB / ID : 3d7p 構造の表示 ダウンロードとリンクタイトル Crystal structure of human Transthyretin (TTR) at pH 4.0 要素Transthyretin 詳細 キーワード TRANSPORT PROTEIN / wt-TTR / AMYLOID / TRANSTHYRETIN / ACIDIC PH / native TTR / and crystal structure / Disease mutation / Gamma-carboxyglutamic acid / Glycoprotein / Hormone / Polymorphism / Polyneuropathy / Retinol-binding / Secreted / Thyroid hormone / Transport / Vitamin A機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation ... Retinoid cycle disease events / The canonical retinoid cycle in rods (twilight vision) / thyroid hormone binding / purine nucleobase metabolic process / Non-integrin membrane-ECM interactions / Retinoid metabolism and transport / hormone activity / azurophil granule lumen / Amyloid fiber formation / Neutrophil degranulation / extracellular space / extracellular exosome / extracellular region / identical protein binding 類似検索 - 分子機能 Transthyretin/hydroxyisourate hydrolase domain / Transthyretin, conserved site / Transthyretin signature 2. / Transthyretin, thyroxine binding site / Transthyretin signature 1. / Transthyretin / Transthyretin/hydroxyisourate hydrolase / Transthyretin/hydroxyisourate hydrolase domain / Transthyretin/hydroxyisourate hydrolase domain superfamily / HIUase/Transthyretin family ... Transthyretin/hydroxyisourate hydrolase domain / Transthyretin, conserved site / Transthyretin signature 2. / Transthyretin, thyroxine binding site / Transthyretin signature 1. / Transthyretin / Transthyretin/hydroxyisourate hydrolase / Transthyretin/hydroxyisourate hydrolase domain / Transthyretin/hydroxyisourate hydrolase domain superfamily / HIUase/Transthyretin family / Immunoglobulin-like / Sandwich / Mainly Beta 類似検索 - ドメイン・相同性生物種 Homo sapiens (ヒト)手法 X線回折 / 分子置換 / 解像度 : 1.72 Å 詳細データ登録者 Palaninathan, S.K. / Mohamedmohaideen, N.N. / Snee, W.C. / Kelly, J.W. / Sacchettini, J.C. 引用ジャーナル : J.Mol.Biol. / 年 : 2008タイトル : Structural insight into pH-induced conformational changes within the native human transthyretin tetramer.著者 : Palaninathan, S.K. / Mohamedmohaideen, N.N. / Snee, W.C. / Kelly, J.W. / Sacchettini, J.C. 履歴 登録 2008年5月21日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2008年8月12日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2023年8月30日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / pdbx_struct_special_symmetry Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession
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