登録情報 データベース : PDB / ID : 3ce6 構造の表示 ダウンロードとリンクタイトル Crystal structure of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with NAD and adenosine 要素Adenosylhomocysteinase 詳細 キーワード HYDROLASE / Protein-substrate complex / dimer of dimers / NAD binding domain / 37 amino acid insertional region / One-carbon metabolism機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
adenosylhomocysteinase / methionine catabolic process / adhesion of symbiont to host cell / adenosine metabolic process / adenosylhomocysteinase / adenosylhomocysteinase activity / entry of bacterium into host cell / S-adenosylmethionine cycle / zymogen binding / NAD+ binding ... adenosylhomocysteinase / methionine catabolic process / adhesion of symbiont to host cell / adenosine metabolic process / adenosylhomocysteinase / adenosylhomocysteinase activity / entry of bacterium into host cell / S-adenosylmethionine cycle / zymogen binding / NAD+ binding / peptidoglycan-based cell wall / one-carbon metabolic process / extracellular region / plasma membrane / cytoplasm / cytosol 類似検索 - 分子機能 Adenosylhomocysteinase-like / Adenosylhomocysteinase-like / S-adenosyl-L-homocysteine hydrolase, conserved site / Adenosylhomocysteinase-like superfamily / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase signature 1. / S-adenosyl-L-homocysteine hydrolase signature 2. / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase, NAD binding domain ... Adenosylhomocysteinase-like / Adenosylhomocysteinase-like / S-adenosyl-L-homocysteine hydrolase, conserved site / Adenosylhomocysteinase-like superfamily / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase signature 1. / S-adenosyl-L-homocysteine hydrolase signature 2. / S-adenosyl-L-homocysteine hydrolase / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / S-adenosyl-L-homocysteine hydrolase, NAD binding domain / NAD(P)-binding Rossmann-like Domain / NAD(P)-binding domain superfamily / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性 ADENOSINE / NICOTINAMIDE-ADENINE-DINUCLEOTIDE / Adenosylhomocysteinase / Adenosylhomocysteinase 類似検索 - 構成要素生物種 Mycobacterium tuberculosis (結核菌)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 1.6 Å 詳細データ登録者 Reddy, M.C.M. / Gokulan, K. / Shetty, N.D. / Owen, J.L. / Ioerger, T.R. / Sacchettini, J.C. 引用ジャーナル : Protein Sci. / 年 : 2008タイトル : Crystal structures of Mycobacterium tuberculosis S-adenosyl-L-homocysteine hydrolase in ternary complex with substrate and inhibitors.著者 : Reddy, M.C. / Kuppan, G. / Shetty, N.D. / Owen, J.L. / Ioerger, T.R. / Sacchettini, J.C. 履歴 登録 2008年2月28日 登録サイト : RCSB / 処理サイト : RCSB改定 1.0 2008年9月16日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Source and taxonomy / Version format compliance改定 1.2 2023年8月30日 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Refinement description カテゴリ : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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