登録情報 | データベース: PDB / ID: 3b82 |
---|
タイトル | Structure of the eEF2-ExoA(E546H)-NAD+ complex |
---|
要素 | - Elongation factor 2
- Exotoxin A
|
---|
キーワード | BIOSYNTHETIC PROTEIN/TRANSFERASE / elongation factor / toxin / ADP-ribosylation / toxin-substrate complex / Cytoplasm / GTP-binding / Nucleotide-binding / Phosphorylation / Protein biosynthesis / RNA-binding / rRNA-binding / Glycosyltransferase / NAD / Transferase / BIOSYNTHETIC PROTEIN-TRANSFERASE COMPLEX |
---|
機能・相同性 | 機能・相同性情報
NAD+-diphthamide ADP-ribosyltransferase / NAD+-diphthamide ADP-ribosyltransferase activity / Peptide chain elongation / Synthesis of diphthamide-EEF2 / positive regulation of translational elongation / Protein methylation / translational elongation / translation elongation factor activity / Neutrophil degranulation / nucleotidyltransferase activity ...NAD+-diphthamide ADP-ribosyltransferase / NAD+-diphthamide ADP-ribosyltransferase activity / Peptide chain elongation / Synthesis of diphthamide-EEF2 / positive regulation of translational elongation / Protein methylation / translational elongation / translation elongation factor activity / Neutrophil degranulation / nucleotidyltransferase activity / 加水分解酵素; 酸無水物に作用; GTPに作用・細胞または細胞小器官の運動に関与 / maintenance of translational fidelity / ribosome binding / protein-folding chaperone binding / toxin activity / rRNA binding / ribonucleoprotein complex / GTPase activity / GTP binding / identical protein binding / cytosol類似検索 - 分子機能 Yeast translation eEF2 (G' domain) / Yeast translation eEF2 (G' domain) / Exotoxin A catalytic domain / Exotoxin A, binding / Exotoxin A, middle domain / Exotoxin A, middle domain superfamily / Exotoxin A catalytic / Exotoxin A binding / Exotoxin A, targeting / Diphtheria Toxin; domain 1 ...Yeast translation eEF2 (G' domain) / Yeast translation eEF2 (G' domain) / Exotoxin A catalytic domain / Exotoxin A, binding / Exotoxin A, middle domain / Exotoxin A, middle domain superfamily / Exotoxin A catalytic / Exotoxin A binding / Exotoxin A, targeting / Diphtheria Toxin; domain 1 / Diphtheria Toxin, domain 1 / Elongation Factor G (Translational Gtpase), domain 3 / Alpha-Beta Plaits - #240 / Ribosomal Protein S5; domain 2 - #10 / Elongation Factor G, domain II / Elongation Factor G, domain III / Translation factors / Translation elongation factor EFG/EF2, domain IV / Elongation factor G, domain IV / Elongation factor G, domain IV / Elongation factor G C-terminus / Elongation factor EFG, domain V-like / Elongation factor G C-terminus / Ribosomal Protein S5; domain 2 / EF-G domain III/V-like / Tr-type G domain, conserved site / Translational (tr)-type guanine nucleotide-binding (G) domain signature. / Translation elongation factor EFTu-like, domain 2 / Elongation factor Tu domain 2 / Elongation Factor Tu (Ef-tu); domain 3 / Translational (tr)-type GTP-binding domain / Elongation factor Tu GTP binding domain / Translational (tr)-type guanine nucleotide-binding (G) domain profile. / Small GTP-binding protein domain / Concanavalin A-like lectin/glucanase domain superfamily / Translation protein, beta-barrel domain superfamily / Ribosomal protein S5 domain 2-type fold, subgroup / P-loop containing nucleotide triphosphate hydrolases / Ribosomal protein S5 domain 2-type fold / Alpha-Beta Plaits / Alpha-Beta Complex / Beta Barrel / Rossmann fold / P-loop containing nucleoside triphosphate hydrolase / 2-Layer Sandwich / 3-Layer(aba) Sandwich / Mainly Beta / Alpha Beta類似検索 - ドメイン・相同性 NICOTINAMIDE-ADENINE-DINUCLEOTIDE / Exotoxin A / Elongation factor 2類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_bacteria.gif) Pseudomonas aeruginosa (緑膿菌)
![](img/tx_yeast.gif) Saccharomyces cerevisiae (パン酵母) |
---|
手法 | X線回折 / シンクロトロン / 解像度: 2.35 Å |
---|
データ登録者 | Jorgensen, R. / Merrill, A.R. |
---|
引用 | ジャーナル: Embo Rep. / 年: 2008 タイトル: The nature and character of the transition state for the ADP-ribosyltransferase reaction. 著者: Jorgensen, R. / Wang, Y. / Visschedyk, D. / Merrill, A.R. |
---|
履歴 | 登録 | 2007年10月31日 | 登録サイト: RCSB / 処理サイト: RCSB |
---|
改定 1.0 | 2008年6月17日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2011年7月13日 | Group: Version format compliance |
---|
改定 1.2 | 2021年10月20日 | Group: Database references / Derived calculations カテゴリ: database_2 / struct_conn ...database_2 / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_leaving_atom_flag / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
---|
改定 1.3 | 2023年8月30日 | Group: Data collection / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model |
---|
|
---|