登録情報 データベース : PDB / ID : 2zne 構造の表示 ダウンロードとリンクタイトル Crystal structure of Zn2+-bound form of des3-23ALG-2 complexed with Alix ABS peptide 要素16-meric peptide from Programmed cell death 6-interacting protein Programmed cell death protein 6 詳細キーワード APOPTOSIS / PENTA-EF-HAND PROTEIN / CALCIUM BINDING PROTEIN / Endoplasmic reticulum / Membrane / Nucleus / Polymorphism / Cytoplasm / Host-virus interaction / Protein transport / Transport機能・相同性 機能・相同性情報分子機能 ドメイン・相同性 構成要素
proteinase activated receptor binding / actomyosin contractile ring assembly / ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway / regulation of extracellular exosome assembly / neural crest formation / viral budding / extracellular exosome biogenesis / maintenance of epithelial cell apical/basal polarity / positive regulation of extracellular exosome assembly / regulation of membrane permeability ... proteinase activated receptor binding / actomyosin contractile ring assembly / ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway / regulation of extracellular exosome assembly / neural crest formation / viral budding / extracellular exosome biogenesis / maintenance of epithelial cell apical/basal polarity / positive regulation of extracellular exosome assembly / regulation of membrane permeability / vascular endothelial growth factor receptor-2 signaling pathway / neural crest cell development / regulation of centrosome duplication / COPII vesicle coat / COPII vesicle coating / midbody abscission / multivesicular body sorting pathway / bicellular tight junction assembly / actomyosin / positive regulation of exosomal secretion / multivesicular body assembly / Flemming body / negative regulation of TOR signaling / positive regulation of protein monoubiquitination / RIPK1-mediated regulated necrosis / Cul3-RING ubiquitin ligase complex / negative regulation of vascular endothelial growth factor receptor signaling pathway / viral budding via host ESCRT complex / positive regulation of cysteine-type endopeptidase activity involved in apoptotic process / endoplasmic reticulum exit site / Uptake and function of anthrax toxins / mitotic cytokinesis / immunological synapse / negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction / ubiquitin-like ligase-substrate adaptor activity / bicellular tight junction / endoplasmic reticulum to Golgi vesicle-mediated transport / protein-membrane adaptor activity / positive regulation of endothelial cell proliferation / positive regulation of endothelial cell migration / macroautophagy / apoptotic signaling pathway / intracellular protein transport / Budding and maturation of HIV virion / protein homooligomerization / Regulation of necroptotic cell death / response to calcium ion / positive regulation of angiogenesis / calcium-dependent protein binding / extracellular vesicle / melanosome / protein transport / protein-macromolecule adaptor activity / cellular response to heat / cytoplasmic vesicle / angiogenesis / protein dimerization activity / endosome / protein heterodimerization activity / focal adhesion / centrosome / calcium ion binding / endoplasmic reticulum membrane / apoptotic process / perinuclear region of cytoplasm / magnesium ion binding / endoplasmic reticulum / protein homodimerization activity / extracellular exosome / nucleoplasm / identical protein binding / membrane / nucleus / cytosol / cytoplasm 類似検索 - 分子機能 : / Vacuolar protein-sorting protein Bro1-like / ALIX V-shaped domain / ALIX V-shaped domain binding to HIV / BRO1 domain / BRO1 domain superfamily / BRO1-like domain / BRO1 domain profile. / BRO1-like domain / EF hand ... : / Vacuolar protein-sorting protein Bro1-like / ALIX V-shaped domain / ALIX V-shaped domain binding to HIV / BRO1 domain / BRO1 domain superfamily / BRO1-like domain / BRO1 domain profile. / BRO1-like domain / EF hand / EF-hand / Recoverin; domain 1 / EF-hand domain pair / EF-hand, calcium binding motif / EF-Hand 1, calcium-binding site / EF-hand calcium-binding domain. / EF-hand calcium-binding domain profile. / EF-hand domain / EF-hand domain pair / Orthogonal Bundle / Mainly Alpha 類似検索 - ドメイン・相同性 Programmed cell death protein 6 / Programmed cell death 6-interacting protein 類似検索 - 構成要素生物種 Homo sapiens (ヒト)手法 X線回折 / シンクロトロン / 分子置換 / 解像度 : 2.2 Å 詳細データ登録者 Suzuki, H. / Kawasaki, M. / Inuzuka, T. / Kakiuchi, T. / Shibata, H. / Wakatsuki, S. / Maki, M. 引用ジャーナル : Structure / 年 : 2008タイトル : Structural Basis for Ca(2+)-Dependent Formation of ALG-2/Alix Peptide Complex: Ca(2+)/EF3-Driven Arginine Switch Mechanism著者 : Suzuki, H. / Kawasaki, M. / Inuzuka, T. / Okumura, M. / Kakiuchi, T. / Shibata, H. / Wakatsuki, S. / Maki, M. 履歴 登録 2008年4月22日 登録サイト : PDBJ / 処理サイト : PDBJ改定 1.0 2008年9月9日 Provider : repository / タイプ : Initial release改定 1.1 2011年7月13日 Group : Version format compliance改定 1.2 2021年11月10日 Group : Database references / Derived calculations / カテゴリ : database_2 / struct_ref_seq_dif / struct_siteItem : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id 改定 1.3 2023年11月1日 Group : Data collection / Refinement descriptionカテゴリ : chem_comp_atom / chem_comp_bond / pdbx_initial_refinement_model
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