Entry | Database: PDB / ID: 2xhs |
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Title | Crystal structure of the ligand binding domain of Fushi tarazu factor 1 of Drosophila melanogaster. |
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Components | - NUCLEAR HORMONE RECEPTOR FTZ-F1
- SEGMENTATION PROTEIN FUSHI TARAZU
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Keywords | TRANSCRIPTION |
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Function / homology | Function and homology information
pupation / instar larval or pupal development / juvenile hormone mediated signaling pathway / periodic partitioning by pair rule gene / SUMOylation of intracellular receptors / Nuclear Receptor transcription pathway / response to ecdysone / gonadal mesoderm development / pupariation / imaginal disc-derived leg morphogenesis ...pupation / instar larval or pupal development / juvenile hormone mediated signaling pathway / periodic partitioning by pair rule gene / SUMOylation of intracellular receptors / Nuclear Receptor transcription pathway / response to ecdysone / gonadal mesoderm development / pupariation / imaginal disc-derived leg morphogenesis / regulation of development, heterochronic / mushroom body development / metamorphosis / segmentation / cell death / tissue development / germ cell migration / dendrite morphogenesis / cell fate specification / anterior/posterior pattern specification / neuron remodeling / lipid homeostasis / transcription factor binding / hormone-mediated signaling pathway / response to hormone / central nervous system development / RNA polymerase II transcription regulator complex / nuclear receptor activity / DNA-binding transcription activator activity, RNA polymerase II-specific / transcription cis-regulatory region binding / DNA-binding transcription factor activity, RNA polymerase II-specific / protein heterodimerization activity / RNA polymerase II cis-regulatory region sequence-specific DNA binding / chromatin binding / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / DNA binding / zinc ion binding / nucleus / cytoplasmSimilarity search - Function Fushi tarazu, N-terminal / Fushi tarazu (FTZ), N-terminal region / Nuclear hormone receptor family 5 / Homeobox domain, metazoa / Homeobox, conserved site / 'Homeobox' domain signature. / Homeodomain / 'Homeobox' domain profile. / Homeodomain / Homeobox domain ...Fushi tarazu, N-terminal / Fushi tarazu (FTZ), N-terminal region / Nuclear hormone receptor family 5 / Homeobox domain, metazoa / Homeobox, conserved site / 'Homeobox' domain signature. / Homeodomain / 'Homeobox' domain profile. / Homeodomain / Homeobox domain / Retinoid X Receptor / Retinoid X Receptor / Homeobox-like domain superfamily / Nuclear hormone receptor / Nuclear hormones receptors DNA-binding region signature. / Zinc finger, nuclear hormone receptor-type / Zinc finger, C4 type (two domains) / Nuclear hormone receptors DNA-binding domain profile. / c4 zinc finger in nuclear hormone receptors / Nuclear hormone receptor, ligand-binding domain / Nuclear hormone receptor-like domain superfamily / Ligand-binding domain of nuclear hormone receptor / Nuclear receptor (NR) ligand-binding (LBD) domain profile. / Ligand binding domain of hormone receptors / Zinc finger, NHR/GATA-type / Orthogonal Bundle / Mainly AlphaSimilarity search - Domain/homology |
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Biological species | DROSOPHILA MELANOGASTER (fruit fly) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MAD / Resolution: 2.8 Å |
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Authors | Yoo, J.H. / Cho, H.S. |
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Citation | Journal: J.Biol.Chem. / Year: 2011 Title: Crystal Structure of Fushi Tarazu Factor 1 Ligand Binding Domain/Fushi Tarazu Peptide Complex Identifies New Class of Nuclear Receptors. Authors: Yoo, J. / Ko, S. / Kim, H. / Sampson, H. / Yun, J.H. / Choe, K.M. / Chang, I. / Arrowsmith, C.H. / Krause, H.M. / Cho, H.S. / Lee, W. |
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History | Deposition | Jun 21, 2010 | Deposition site: PDBE / Processing site: PDBE |
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Supersession | Jul 20, 2011 | ID: 2IZ2 |
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Revision 1.0 | Jul 20, 2011 | Provider: repository / Type: Initial release |
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Revision 1.1 | Sep 14, 2011 | Group: Database references |
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Revision 1.2 | Jun 20, 2018 | Group: Advisory / Data collection / Derived calculations Category: pdbx_unobs_or_zero_occ_atoms / pdbx_validate_close_contact / struct_conn |
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