Entry Database : PDB / ID : 2x7h Structure visualization Downloads & linksTitle Crystal structure of the human MGC45594 gene product in complex with fenoprofen ComponentsZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2 Details Keywords OXIDOREDUCTASEFunction / homology Function and homology informationFunction Domain/homology Component
13,14-dehydro-15-oxoprostaglandin 13-reductase / 15-oxoprostaglandin 13-oxidase [NAD(P)+] activity / : / negative regulation of fat cell differentiation / peroxisome / mitochondrion / zinc ion binding Similarity search - Function Quinone oxidoreductase/zeta-crystallin, conserved site / Quinone oxidoreductase / zeta-crystallin signature. / Quinone Oxidoreductase; Chain A, domain 1 / Medium-chain alcohol dehydrogenases, catalytic domain / Alcohol dehydrogenase-like, C-terminal / Zinc-binding dehydrogenase / Alcohol dehydrogenase, N-terminal / Alcohol dehydrogenase GroES-like domain / Polyketide synthase, enoylreductase domain / Enoylreductase ... Quinone oxidoreductase/zeta-crystallin, conserved site / Quinone oxidoreductase / zeta-crystallin signature. / Quinone Oxidoreductase; Chain A, domain 1 / Medium-chain alcohol dehydrogenases, catalytic domain / Alcohol dehydrogenase-like, C-terminal / Zinc-binding dehydrogenase / Alcohol dehydrogenase, N-terminal / Alcohol dehydrogenase GroES-like domain / Polyketide synthase, enoylreductase domain / Enoylreductase / GroES-like superfamily / NAD(P)-binding Rossmann-like Domain / NAD(P)-binding domain superfamily / Alpha-Beta Complex / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homologyBiological species HOMO SAPIENS (human)Method X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution : 1.6 Å DetailsAuthors Shafqat, N. / Yue, W.W. / Ugochukwu, E. / Niesen, F. / Vollmar, M. / Chaikuad, A. / Pike, A.C.W. / von Delft, F. / Smee, C. / Arrowsmith, C. ...Shafqat, N. / Yue, W.W. / Ugochukwu, E. / Niesen, F. / Vollmar, M. / Chaikuad, A. / Pike, A.C.W. / von Delft, F. / Smee, C. / Arrowsmith, C. / Weigelt, J. / Edwards, A. / Bountra, C. / Oppermann, U. CitationJournal : To be Published Title : Crystal Structure of the Human Mgc45594 Gene Product in Complex with FenoprofenAuthors : Shafqat, N. / Yue, W.W. / Ugochukwu, E. / Niesen, F. / Vollmar, M. / Chaikuad, A. / Pike, A.C.W. / von Delft, F. / Smee, C. / Arrowsmith, C. / Weigelt, J. / Edwards, A. / Bountra, C. / Oppermann, U. History Deposition Feb 26, 2010 Deposition site : PDBE / Processing site : PDBERevision 1.0 Dec 8, 2010 Provider : repository / Type : Initial releaseRevision 1.1 Dec 5, 2012 Group : Database references / Derived calculations ... Database references / Derived calculations / Other / Structure summary / Version format compliance Revision 1.2 Jan 24, 2018 Group : Database references / Category : citation_author / Item : _citation_author.nameRevision 1.3 Dec 20, 2023 Group : Data collection / Database references ... Data collection / Database references / Derived calculations / Other / Refinement description Category : chem_comp_atom / chem_comp_bond ... chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / struct_site Item : _database_2.pdbx_DOI / _database_2.pdbx_database_accession ... _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id
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