Entry | Database: PDB / ID: 2wm5 |
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Title | X-ray structure of the substrate-free Mycobacterium tuberculosis cytochrome P450 CYP124 |
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Components | PUTATIVE CYTOCHROME P450 124 |
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Keywords | OXIDOREDUCTASE / METAL-BINDING / OMEGA-HYDROXYLATION / P450 / IRON / HEME / FATTY ACID / MONOOXYGENASE |
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Function / homology | Function and homology information
methyl-branched lipid omega-hydroxylase / methyl-branched fatty acid metabolic process / cholesterol 26-hydroxylase activity / cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming] / fatty acid omega-oxidation / cholest-4-en-3-one 26-monooxygenase activity / NADPH binding / iron ion binding / heme bindingSimilarity search - Function Cytochrome P450, B-class / Cytochrome p450 / Cytochrome P450 / Cytochrome P450 / Cytochrome P450 superfamily / Cytochrome P450 / Orthogonal Bundle / Mainly AlphaSimilarity search - Domain/homology |
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Biological species | ![](img/tx_bacteria.gif) MYCOBACTERIUM TUBERCULOSIS (bacteria) |
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Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 1.5 Å |
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Authors | Johnston, J.B. / Kells, P.M. / Podust, L.M. / Ortiz de Montellano, P.R. |
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Citation | Journal: Proc. Natl. Acad. Sci. U.S.A. / Year: 2009 Title: Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. Authors: Johnston, J.B. / Kells, P.M. / Podust, L.M. / Ortiz de Montellano, P.R. |
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History | Deposition | Jun 30, 2009 | Deposition site: PDBE / Processing site: PDBE |
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Revision 1.0 | Oct 6, 2009 | Provider: repository / Type: Initial release |
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Revision 1.1 | Dec 7, 2011 | Group: Database references / Non-polymer description / Version format compliance |
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Revision 1.2 | Feb 28, 2018 | Group: Database references / Source and taxonomy / Category: citation / citation_author / entity_src_gen Item: _citation.journal_abbrev / _citation.journal_id_ISSN ..._citation.journal_abbrev / _citation.journal_id_ISSN / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _citation_author.name / _entity_src_gen.pdbx_host_org_ncbi_taxonomy_id / _entity_src_gen.pdbx_host_org_scientific_name / _entity_src_gen.pdbx_host_org_strain |
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Revision 1.3 | May 1, 2024 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Other / Refinement description Category: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model / pdbx_struct_conn_angle / struct_conn / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf / _pdbx_struct_conn_angle.ptnr1_auth_comp_id / _pdbx_struct_conn_angle.ptnr1_auth_seq_id / _pdbx_struct_conn_angle.ptnr1_label_asym_id / _pdbx_struct_conn_angle.ptnr1_label_atom_id / _pdbx_struct_conn_angle.ptnr1_label_comp_id / _pdbx_struct_conn_angle.ptnr1_label_seq_id / _pdbx_struct_conn_angle.ptnr3_auth_comp_id / _pdbx_struct_conn_angle.ptnr3_auth_seq_id / _pdbx_struct_conn_angle.ptnr3_label_asym_id / _pdbx_struct_conn_angle.ptnr3_label_atom_id / _pdbx_struct_conn_angle.ptnr3_label_comp_id / _pdbx_struct_conn_angle.ptnr3_label_seq_id / _pdbx_struct_conn_angle.value / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_conn.ptnr2_label_seq_id / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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