登録情報 | データベース: PDB / ID: 2vge |
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タイトル | Crystal structure of the C-terminal region of human iASPP |
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要素 | RELA-ASSOCIATED INHIBITOR |
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キーワード | TRANSCRIPTION / IASPP / NUCLEUS / APOPTOSIS / REPRESSOR / CYTOPLASM / PHOSPHORYLATION / P53 BINDING PROTEIN / ANK REPEAT / SH3 DOMAIN / ANKYRIN REPEATS / ALTERNATIVE SPLICING / TRANSCRIPTION REGULATION |
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機能・相同性 | 機能・相同性情報
multicellular organismal-level homeostasis / cardiac right ventricle morphogenesis / embryonic camera-type eye development / hair cycle / ventricular cardiac muscle tissue development / Regulation of TP53 Activity through Association with Co-factors / intercellular bridge / cardiac muscle contraction / post-embryonic development / positive regulation of cell differentiation ...multicellular organismal-level homeostasis / cardiac right ventricle morphogenesis / embryonic camera-type eye development / hair cycle / ventricular cardiac muscle tissue development / Regulation of TP53 Activity through Association with Co-factors / intercellular bridge / cardiac muscle contraction / post-embryonic development / positive regulation of cell differentiation / negative regulation of inflammatory response / multicellular organism growth / transcription corepressor activity / cell junction / cadherin binding / regulation of transcription by RNA polymerase II / apoptotic process / negative regulation of transcription by RNA polymerase II / nucleoplasm / identical protein binding / nucleus / cytosol類似検索 - 分子機能 RelA-associated inhibitor / RelA-associated inhibitor, SH3 domain / Variant SH3 domain / Ankyrin repeat-containing domain / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily ...RelA-associated inhibitor / RelA-associated inhibitor, SH3 domain / Variant SH3 domain / Ankyrin repeat-containing domain / Ankyrin repeats (3 copies) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Src homology 3 domains / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Alpha Horseshoe / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | HOMO SAPIENS (ヒト) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.1 Å |
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データ登録者 | Robinson, R.A. / Lu, X. / Jones, E.Y. / Siebold, C. |
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引用 | ジャーナル: Structure / 年: 2008 タイトル: Biochemical and Structural Studies of Aspp Proteins Reveal Differential Binding to P53, P63 and P73 著者: Robinson, R.A. / Lu, X. / Jones, E.Y. / Siebold, C. |
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履歴 | 登録 | 2007年11月12日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2008年2月5日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年5月8日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2023年12月13日 | Group: Data collection / Database references ...Data collection / Database references / Other / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_database_status / pdbx_initial_refinement_model Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_sf |
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