- PDB-2rvb: Solution structure of the complex between XPC acidic domain and T... -
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Basic information
Entry
Database: PDB / ID: 2rvb
Title
Solution structure of the complex between XPC acidic domain and TFIIH p62 PH domain
Components
DNA repair protein complementing XP-C cells
General transcription factor IIH subunit 1
Keywords
DNA BINDING PROTEIN/TRANSCRIPTION / DNA REPAIR / HUMAN XPC / ACIDIC DOMAIN / GENERAL TRANSCRIPTION FACTOR / HUMAN TFIIH P62 / PH DOMAIN / DNA BINDING PROTEIN-TRANSCRIPTION complex
Function / homology
Function and homology information
heteroduplex DNA loop binding / pyrimidine dimer repair by nucleotide-excision repair / nucleotide-excision repair factor 2 complex / XPC complex / nucleotide-excision repair complex / DNA damage sensor activity / response to auditory stimulus / bubble DNA binding / UV-damage excision repair / transcription factor TFIIH core complex ...heteroduplex DNA loop binding / pyrimidine dimer repair by nucleotide-excision repair / nucleotide-excision repair factor 2 complex / XPC complex / nucleotide-excision repair complex / DNA damage sensor activity / response to auditory stimulus / bubble DNA binding / UV-damage excision repair / transcription factor TFIIH core complex / transcription factor TFIIH holo complex / response to UV-B / mitotic intra-S DNA damage checkpoint signaling / nuclear thyroid hormone receptor binding / RNA Polymerase I Transcription Termination / regulation of mitotic cell cycle phase transition / regulation of cyclin-dependent protein serine/threonine kinase activity / RNA Pol II CTD phosphorylation and interaction with CE during HIV infection / RNA Pol II CTD phosphorylation and interaction with CE / Formation of the Early Elongation Complex / Formation of the HIV-1 Early Elongation Complex / mRNA Capping / HIV Transcription Initiation / RNA Polymerase II HIV Promoter Escape / Transcription of the HIV genome / RNA Polymerase II Promoter Escape / RNA Polymerase II Transcription Pre-Initiation And Promoter Opening / RNA Polymerase II Transcription Initiation / RNA Polymerase II Transcription Initiation And Promoter Clearance / site of DNA damage / RNA Polymerase I Transcription Initiation / transcription by RNA polymerase I / Tat-mediated elongation of the HIV-1 transcript / Formation of HIV-1 elongation complex containing HIV-1 Tat / hormone-mediated signaling pathway / Formation of HIV elongation complex in the absence of HIV Tat / mismatch repair / SUMOylation of DNA damage response and repair proteins / RNA Polymerase II Transcription Elongation / Formation of RNA Pol II elongation complex / RNA Polymerase II Pre-transcription Events / RNA Polymerase I Promoter Escape / nucleotide-excision repair / transcription initiation at RNA polymerase II promoter / TP53 Regulates Transcription of DNA Repair Genes / NoRC negatively regulates rRNA expression / DNA Damage Recognition in GG-NER / Transcription-Coupled Nucleotide Excision Repair (TC-NER) / Formation of TC-NER Pre-Incision Complex / Dual Incision in GG-NER / Formation of Incision Complex in GG-NER / Dual incision in TC-NER / Gap-filling DNA repair synthesis and ligation in TC-NER / single-stranded DNA binding / transcription coactivator activity / RNA polymerase II-specific DNA-binding transcription factor binding / transcription by RNA polymerase II / damaged DNA binding / response to xenobiotic stimulus / intracellular membrane-bounded organelle / DNA repair / chromatin binding / positive regulation of DNA-templated transcription / chromatin / protein-containing complex binding / nucleolus / mitochondrion / nucleoplasm / nucleus / plasma membrane / cytoplasm / cytosol Similarity search - Function
Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 100 / Conformers submitted total number: 20 / Representative conformer: 1
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