- PDB-2rnx: The Structural Basis for Site-Specific Lysine-Acetylated Histone ... -
+
データを開く
IDまたはキーワード:
読み込み中...
-
基本情報
登録情報
データベース: PDB / ID: 2rnx
タイトル
The Structural Basis for Site-Specific Lysine-Acetylated Histone Recognition by the Bromodomains of the HUman Transcriptional Co-Activators PCAF and CBP
要素
Histone H3
Histone acetyltransferase PCAF
キーワード
TRANSFERASE/NUCLEAR PROTEIN / Bromodomain / Histone / Acetyltransferase / Acyltransferase / Cell cycle / Host-virus interaction / Nucleus / Polymorphism / Transcription / Transcription regulation / Acetylation / Chromosomal protein / DNA damage / DNA repair / DNA-binding / Methylation / Nucleosome core / Phosphoprotein / TRANSFERASE-NUCLEAR PROTEIN COMPLEX
機能・相同性
機能・相同性情報
sexual sporulation resulting in formation of a cellular spore / regulation of protein ADP-ribosylation / negative regulation of rRNA processing / histone H3K9 acetyltransferase activity / diamine N-acetyltransferase / global genome nucleotide-excision repair / RNA polymerase I upstream activating factor complex / positive regulation of transcription from RNA polymerase II promoter by glucose / diamine N-acetyltransferase activity / negative regulation of centriole replication ...sexual sporulation resulting in formation of a cellular spore / regulation of protein ADP-ribosylation / negative regulation of rRNA processing / histone H3K9 acetyltransferase activity / diamine N-acetyltransferase / global genome nucleotide-excision repair / RNA polymerase I upstream activating factor complex / positive regulation of transcription from RNA polymerase II promoter by glucose / diamine N-acetyltransferase activity / negative regulation of centriole replication / positive regulation of attachment of mitotic spindle microtubules to kinetochore / Physiological factors / Condensation of Prophase Chromosomes / SIRT1 negatively regulates rRNA expression / peptidyl-lysine acetylation / Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 / lysine N-acetyltransferase activity, acting on acetyl phosphate as donor / Assembly of the ORC complex at the origin of replication / YAP1- and WWTR1 (TAZ)-stimulated gene expression / positive regulation of fatty acid biosynthetic process / actomyosin / internal peptidyl-lysine acetylation / histone H3 acetyltransferase activity / cyclin-dependent protein serine/threonine kinase inhibitor activity / replication fork protection complex / N-terminal peptidyl-lysine acetylation / Oxidative Stress Induced Senescence / ATAC complex / I band / cellular response to parathyroid hormone stimulus / Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells / RUNX3 regulates NOTCH signaling / SAGA complex / limb development / Regulation of FOXO transcriptional activity by acetylation / NOTCH4 Intracellular Domain Regulates Transcription / A band / NOTCH3 Intracellular Domain Regulates Transcription / peptide-lysine-N-acetyltransferase activity / regulation of tubulin deacetylation / histone acetyltransferase binding / positive regulation of transcription by RNA polymerase I / protein acetylation / Notch-HLH transcription pathway / Formation of WDR5-containing histone-modifying complexes / Formation of paraxial mesoderm / regulation of cell division / RNA Polymerase I Promoter Escape / nucleolar large rRNA transcription by RNA polymerase I / RNA Polymerase I Transcription Initiation / Estrogen-dependent gene expression / rRNA transcription / regulation of RNA splicing / regulation of embryonic development / acetyltransferase activity / regulation of DNA repair / CENP-A containing nucleosome / histone acetyltransferase activity / histone acetyltransferase / positive regulation of gluconeogenesis / transcription initiation-coupled chromatin remodeling / positive regulation of glycolytic process / gluconeogenesis / transcription coregulator activity / RNA polymerase II transcription regulatory region sequence-specific DNA binding / RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function / B-WICH complex positively regulates rRNA expression / NOTCH1 Intracellular Domain Regulates Transcription / Metalloprotease DUBs / mitotic spindle / memory / kinetochore / Pre-NOTCH Transcription and Translation / Constitutive Signaling by NOTCH1 PEST Domain Mutants / Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants / positive regulation of neuron projection development / histone deacetylase binding / vasodilation / cellular response to insulin stimulus / structural constituent of chromatin / nucleosome / rhythmic process / chromatin organization / heart development / HATs acetylate histones / cellular response to oxidative stress / DNA-binding transcription factor binding / Estrogen-dependent gene expression / transcription coactivator activity / regulation of cell cycle / chromatin remodeling / cell cycle / protein heterodimerization activity / negative regulation of cell population proliferation / centrosome / chromatin binding / regulation of DNA-templated transcription / regulation of transcription by RNA polymerase II / protein kinase binding / positive regulation of DNA-templated transcription 類似検索 - 分子機能