登録情報 | データベース: PDB / ID: 2rll |
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タイトル | CCR5 Nt(7-15) |
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要素 | 9-mer from C-C chemokine receptor type 5 |
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キーワード | MEMBRANE PROTEIN / HIV-1 coreceptor CCR5 N-terminus bound to gp120:CD4 / G-protein coupled receptor / Glycoprotein / Host-virus interaction / Membrane / Polymorphism / Sulfation / Transducer / Transmembrane |
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機能・相同性 | 機能・相同性情報
chemokine (C-C motif) ligand 5 binding / negative regulation of macrophage apoptotic process / chemokine receptor activity / signaling / C-C chemokine receptor activity / phosphatidylinositol-4,5-bisphosphate phospholipase C activity / C-C chemokine binding / response to cholesterol / Chemokine receptors bind chemokines / release of sequestered calcium ion into cytosol by sarcoplasmic reticulum ...chemokine (C-C motif) ligand 5 binding / negative regulation of macrophage apoptotic process / chemokine receptor activity / signaling / C-C chemokine receptor activity / phosphatidylinositol-4,5-bisphosphate phospholipase C activity / C-C chemokine binding / response to cholesterol / Chemokine receptors bind chemokines / release of sequestered calcium ion into cytosol by sarcoplasmic reticulum / dendritic cell chemotaxis / Interleukin-10 signaling / Binding and entry of HIV virion / cellular defense response / coreceptor activity / cell chemotaxis / calcium-mediated signaling / chemotaxis / calcium ion transport / MAPK cascade / cell-cell signaling / actin binding / virus receptor activity / positive regulation of cytosolic calcium ion concentration / cellular response to lipopolysaccharide / G alpha (i) signalling events / cell surface receptor signaling pathway / endosome / immune response / G protein-coupled receptor signaling pathway / inflammatory response / external side of plasma membrane / apoptotic process / cell surface / identical protein binding / plasma membrane / cytoplasm類似検索 - 分子機能 CC chemokine receptor 5 / Chemokine receptor family / : / G-protein coupled receptors family 1 signature. / G protein-coupled receptor, rhodopsin-like / GPCR, rhodopsin-like, 7TM / G-protein coupled receptors family 1 profile. / 7 transmembrane receptor (rhodopsin family)類似検索 - ドメイン・相同性 |
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手法 | 溶液NMR / torsion angle dynamics |
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Model type details | minimized average |
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データ登録者 | Bewley, C.A. / Lam, S.N. |
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引用 | ジャーナル: Science / 年: 2007 タイトル: Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4 著者: Huang, C.-C. / Lam, S.N. / Acharya, P. / Tang, M. / Xiang, S.-H. / Hussan, S.S. / Stanfield, R.L. / Robinson, J. / Sodroski, J. / Wilson, I.A. / Wyatt, R. / Bewley, C.A. / Kwong, P.D. |
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履歴 | 登録 | 2007年7月21日 | 登録サイト: BMRB / 処理サイト: PDBJ |
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改定 1.0 | 2007年9月25日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2022年3月16日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_software ...database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_conn Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_conn.pdbx_leaving_atom_flag |
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改定 2.0 | 2023年11月15日 | Group: Atomic model / Data collection / カテゴリ: atom_site / chem_comp_atom / chem_comp_bond / Item: _atom_site.auth_atom_id / _atom_site.label_atom_id |
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改定 2.1 | 2024年10月30日 | Group: Structure summary カテゴリ: pdbx_entry_details / pdbx_modification_feature |
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