negative regulation of Arp2/3 complex-mediated actin nucleation / fructose-bisphosphate aldolase / fructose-bisphosphate aldolase activity / M band / I band / fructose 1,6-bisphosphate metabolic process / glycolytic process / protein homotetramerization / positive regulation of cell migration / cytosol Similarity search - Function
Fructose-bisphosphate aldolase class-I active site / Fructose-bisphosphate aldolase class-I active site. / Fructose-bisphosphate aldolase, class-I / Fructose-bisphosphate aldolase class-I / Aldolase class I / Aldolase-type TIM barrel / TIM Barrel / Alpha-Beta Barrel / Alpha Beta Similarity search - Domain/homology
A: Fructose-bisphosphate aldolase A B: Fructose-bisphosphate aldolase A C: Fructose-bisphosphate aldolase A D: Fructose-bisphosphate aldolase A hetero molecules
Mass: 18.015 Da / Num. of mol.: 2230 / Source method: isolated from a natural source / Formula: H2O
Nonpolymer details
REMARK 600 HETEROGEN REMARK 600 13P LIGAND IS COVALENTLY BOUND TO LYS-229 AS A SCHIFF BASE ...REMARK 600 HETEROGEN REMARK 600 13P LIGAND IS COVALENTLY BOUND TO LYS-229 AS A SCHIFF BASE INTERMEDIATE (PROTONATED IMINE).
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Experimental details
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Experiment
Experiment
Method: X-RAY DIFFRACTION / Number of used crystals: 1
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Sample preparation
Crystal
Density Matthews: 2.32 Å3/Da / Density % sol: 47.05 %
Crystal grow
Temperature: 296 K / Method: vapor diffusion, hanging drop / pH: 7.5 Details: sodium HEPES, PEG 4000, pH 7.5, VAPOR DIFFUSION, HANGING DROP, temperature 296K
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