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Yorodumi- PDB-2pnc: Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidas... -
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-Basic information
Entry | Database: PDB / ID: 2pnc | |||||||||
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Title | Crystal Structure of Bovine Plasma Copper-Containing Amine Oxidase in Complex with Clonidine | |||||||||
Components | Copper amine oxidase, liver isozyme | |||||||||
Keywords | OXIDOREDUCTASE / AMINE OXIDASE / QUINOENZYME / TPQ / clonidine | |||||||||
Function / homology | Function and homology information Phase I - Functionalization of compounds / primary-amine oxidase / aliphatic amine oxidase activity / primary methylamine oxidase activity / amine metabolic process / quinone binding / early endosome / copper ion binding / response to antibiotic / Golgi apparatus ...Phase I - Functionalization of compounds / primary-amine oxidase / aliphatic amine oxidase activity / primary methylamine oxidase activity / amine metabolic process / quinone binding / early endosome / copper ion binding / response to antibiotic / Golgi apparatus / endoplasmic reticulum / extracellular region / plasma membrane Similarity search - Function | |||||||||
Biological species | Bos taurus (cattle) | |||||||||
Method | X-RAY DIFFRACTION / SYNCHROTRON / MOLECULAR REPLACEMENT / Resolution: 2.4 Å | |||||||||
Authors | Cendron, L. / Holt, A. / Smith, D.J. / Zanotti, G. / Rigo, A. / Di Paolo, M.L. | |||||||||
Citation | Journal: Mol.Pharmacol. / Year: 2008 Title: Multiple binding sites for substrates and modulators of semicarbazide-sensitive amine oxidases: kinetic consequences Authors: Holt, A. / Smith, D.J. / Cendron, L. / Zanotti, G. / Rigo, A. / Di Paolo, M.L. #1: Journal: J.Mol.Biol. / Year: 2005 Title: Crystal structure of amine oxidase from bovine serum. Authors: Lunelli, M. / Di Paolo, M.L. / Biadene, M. / Calderone, V. / Battistutta, R. / Scarpa, M. / Rigo, A. / Zanotti, G. #2: Journal: Acta Crystallogr.,Sect.D / Year: 2003 Title: Crystallization and Preliminary X-Ray Data of Amine Oxidase from Bovine Serum Authors: Calderone, V. / Di Paolo, M.L. / Trabucco, M. / Biadene, M. / Battistutta, R. / Rigo, A. / Zanotti, G. #3: Journal: Structure / Year: 1995 Title: Crystal Structure of a Quinoenzyme: Copper Amine Oxidase of Escherichia Coli at 2 A Resolution Authors: Parsons, M.R. / Convery, M.A. / Wilmot, C.M. / Yadav, K.D. / Blakeley, V. / Corner, A.S. / Phillips, S.E. / McPherson, M.J. / Knowles, P.F. #4: Journal: Structure / Year: 1996 Title: Crystal Structure of a Eukaryotic (Pea Seedling) Copper-Containing Amine Oxidase at 2.2 A Resolution Authors: Kumar, V. / Dooley, D.M. / Freeman, H.C. / Guss, J.M. / Harvey, I. / Mcguirl, M.A. / Wilce, M.C. / Zubak, V.M. #5: Journal: Biochemistry / Year: 2003 Title: The Crystal Structure of Pichia Pastoris Lysyl Oxidase Authors: Duff, A.P. / Cohen, A.E. / Ellis, P.J. / Kuchar, J.A. / Langley, D.B. / Shepard, E.M. / Dooley, D.M. / Freeman, H.C. / Guss, J.M. | |||||||||
History |
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-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2pnc.cif.gz | 273.5 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2pnc.ent.gz | 216.1 KB | Display | PDB format |
PDBx/mmJSON format | 2pnc.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 2pnc_validation.pdf.gz | 1.1 MB | Display | wwPDB validaton report |
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Full document | 2pnc_full_validation.pdf.gz | 1.1 MB | Display | |
Data in XML | 2pnc_validation.xml.gz | 52.7 KB | Display | |
Data in CIF | 2pnc_validation.cif.gz | 71.4 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/pn/2pnc ftp://data.pdbj.org/pub/pdb/validation_reports/pn/2pnc | HTTPS FTP |
-Related structure data
Related structure data | 1tu5S S: Starting model for refinement |
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Similar structure data |
-Links
-Assembly
Deposited unit |
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Ens-ID: 1 / Refine code: 5
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