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- PDB-2okj: The X-ray crystal structure of the 67kDa isoform of Glutamic Acid... -
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Open data
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Basic information
Entry | Database: PDB / ID: 2okj | |||||||||
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Title | The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) | |||||||||
![]() | Glutamate decarboxylase 1 | |||||||||
![]() | LYASE / PLP-dependent decarboxylase | |||||||||
Function / homology | ![]() GABA synthesis / glutamate decarboxylation to succinate / MECP2 regulates transcription of genes involved in GABA signaling / glutamate decarboxylase / glutamate decarboxylase activity / gamma-aminobutyric acid biosynthetic process / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / GABA synthesis, release, reuptake and degradation / inhibitory synapse / glutamate catabolic process ...GABA synthesis / glutamate decarboxylation to succinate / MECP2 regulates transcription of genes involved in GABA signaling / glutamate decarboxylase / glutamate decarboxylase activity / gamma-aminobutyric acid biosynthetic process / clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane / GABA synthesis, release, reuptake and degradation / inhibitory synapse / glutamate catabolic process / vesicle membrane / presynaptic active zone / locomotory exploration behavior / social behavior / GABA-ergic synapse / axon terminus / pyridoxal phosphate binding / cell cortex / chemical synaptic transmission / identical protein binding / plasma membrane / cytoplasm Similarity search - Function | |||||||||
Biological species | ![]() | |||||||||
Method | ![]() ![]() ![]() | |||||||||
![]() | Buckle, A.M. / Fenalti, G. / Law, R.H.P. / Whisstock, J.C. | |||||||||
![]() | ![]() Title: GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Authors: Fenalti, G. / Law, R.H.P. / Buckle, A.M. / Langendorf, C. / Tuck, K. / Rosado, C.J. / Faux, N.G. / Mahmood, K. / Hampe, C.S. / Banga, J.P. / Wilce, M. / Schmidberger, J. / Rossjohn, J. / El- ...Authors: Fenalti, G. / Law, R.H.P. / Buckle, A.M. / Langendorf, C. / Tuck, K. / Rosado, C.J. / Faux, N.G. / Mahmood, K. / Hampe, C.S. / Banga, J.P. / Wilce, M. / Schmidberger, J. / Rossjohn, J. / El-Kabbani, O. / Pike, R.N. / Smith, A.I. / Mackay, I.R. / Rowley, M.J. / Whisstock, J.C. | |||||||||
History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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Download
PDBx/mmCIF format | ![]() | 219.4 KB | Display | ![]() |
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PDB format | ![]() | 171.1 KB | Display | ![]() |
PDBx/mmJSON format | ![]() | Tree view | ![]() | |
Others | ![]() |
-Validation report
Summary document | ![]() | 468.8 KB | Display | ![]() |
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Full document | ![]() | 481.2 KB | Display | |
Data in XML | ![]() | 40 KB | Display | |
Data in CIF | ![]() | 56.7 KB | Display | |
Arichive directory | ![]() ![]() | HTTPS FTP |
-Related structure data
Related structure data | ![]() 2okkC ![]() 1js3S C: citing same article ( S: Starting model for refinement |
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Similar structure data |
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Assembly
Deposited unit | ![]()
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Unit cell |
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Noncrystallographic symmetry (NCS) | NCS domain:
NCS domain segments: Component-ID: 1
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