登録情報 | データベース: PDB / ID: 2o8g |
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タイトル | Rat pp1c gamma complexed with mouse inhibitor-2 |
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要素 | - Protein phosphatase inhibitor 2
- Serine/threonine-protein phosphatase PP1-gamma catalytic subunit
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キーワード | HYDROLASE/INHIBITOR / protein phosphatase / inhibitor-2 / HYDROLASE-INHIBITOR COMPLEX |
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機能・相同性 | 機能・相同性情報
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / Resolution of Sister Chromatid Cohesion / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / RHO GTPases Activate Formins / RAF activation / Separation of Sister Chromatids / PTW/PP1 phosphatase complex / regulation of nucleocytoplasmic transport / protein phosphatase 1 binding ...Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal / Resolution of Sister Chromatid Cohesion / Mitotic Prometaphase / EML4 and NUDC in mitotic spindle formation / RHO GTPases Activate Formins / RAF activation / Separation of Sister Chromatids / PTW/PP1 phosphatase complex / regulation of nucleocytoplasmic transport / protein phosphatase 1 binding / lamin binding / microtubule organizing center / protein phosphatase inhibitor activity / myosin phosphatase activity / protein serine/threonine phosphatase activity / glycogen metabolic process / molecular function inhibitor activity / protein-serine/threonine phosphatase / entrainment of circadian clock by photoperiod / phosphatase activity / cleavage furrow / blastocyst development / regulation of signal transduction / positive regulation of glial cell proliferation / protein dephosphorylation / circadian regulation of gene expression / neuron differentiation / regulation of circadian rhythm / kinetochore / presynapse / midbody / growth cone / spermatogenesis / postsynapse / protein phosphatase binding / mitochondrial outer membrane / cell cycle / dendritic spine / chromosome, telomeric region / nuclear speck / protein domain specific binding / cell division / glutamatergic synapse / protein-containing complex binding / nucleolus / protein kinase binding / protein-containing complex / mitochondrion / nucleus / metal ion binding / cytoplasm / cytosol類似検索 - 分子機能 Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #1050 / Protein phosphatase inhibitor 2 (IPP-2) / Protein phosphatase inhibitor 2 (IPP-2) / Serine-threonine protein phosphatase, N-terminal / Serine-threonine protein phosphatase N-terminal domain / Serine/threonine specific protein phosphatases signature. / Protein phosphatase 2A homologues, catalytic domain. / Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase / Metallo-dependent phosphatases / Purple Acid Phosphatase; chain A, domain 2 ...Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #1050 / Protein phosphatase inhibitor 2 (IPP-2) / Protein phosphatase inhibitor 2 (IPP-2) / Serine-threonine protein phosphatase, N-terminal / Serine-threonine protein phosphatase N-terminal domain / Serine/threonine specific protein phosphatases signature. / Protein phosphatase 2A homologues, catalytic domain. / Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase / Metallo-dependent phosphatases / Purple Acid Phosphatase; chain A, domain 2 / Calcineurin-like phosphoesterase domain, ApaH type / Calcineurin-like phosphoesterase / Metallo-dependent phosphatase-like / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Helix non-globular / Special / 4-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 : / Serine/threonine-protein phosphatase PP1-gamma catalytic subunit / Protein phosphatase inhibitor 2類似検索 - 構成要素 |
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生物種 | ![](img/tx_mammal.gif) Rattus norvegicus (ドブネズミ)
![](img/tx_mammal.gif) Mus musculus (ハツカネズミ) |
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手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.5 Å |
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データ登録者 | Hurley, T.D. |
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引用 | ジャーナル: J.Biol.Chem. / 年: 2007 タイトル: Structural basis for regulation of protein phosphatase 1 by inhibitor-2. 著者: Hurley, T.D. / Yang, J. / Zhang, L. / Goodwin, K.D. / Zou, Q. / Cortese, M. / Dunker, A.K. / Depaoli-Roach, A.A. |
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履歴 | 登録 | 2006年12月12日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2007年7月17日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2007年10月3日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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改定 1.3 | 2017年10月18日 | Group: Refinement description / カテゴリ: software Item: _software.classification / _software.contact_author ..._software.classification / _software.contact_author / _software.contact_author_email / _software.date / _software.language / _software.location / _software.name / _software.type / _software.version |
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改定 1.4 | 2023年8月30日 | Group: Data collection / Database references ...Data collection / Database references / Derived calculations / Refinement description カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / pdbx_initial_refinement_model / struct_conn / struct_ref_seq_dif / struct_site Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_conn.pdbx_dist_value / _struct_conn.ptnr1_auth_asym_id / _struct_conn.ptnr1_auth_comp_id / _struct_conn.ptnr1_auth_seq_id / _struct_conn.ptnr1_label_asym_id / _struct_conn.ptnr1_label_atom_id / _struct_conn.ptnr1_label_comp_id / _struct_conn.ptnr1_label_seq_id / _struct_conn.ptnr2_auth_asym_id / _struct_conn.ptnr2_auth_comp_id / _struct_conn.ptnr2_auth_seq_id / _struct_conn.ptnr2_label_asym_id / _struct_conn.ptnr2_label_atom_id / _struct_conn.ptnr2_label_comp_id / _struct_ref_seq_dif.details / _struct_site.pdbx_auth_asym_id / _struct_site.pdbx_auth_comp_id / _struct_site.pdbx_auth_seq_id |
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