登録情報 | データベース: PDB / ID: 2na2 |
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タイトル | DROSHA QUAD MUTANT DOUBLE-STRANDED RNA BINDING COMPETENT |
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要素 | Ribonuclease 3 |
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キーワード | NUCLEAR PROTEIN/RNA BINDING PROTEIN / Drosha / HYDROLASE / NUCLEAR PROTEIN-RNA BINDING PROTEIN complex |
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機能・相同性 | 機能・相同性情報
regulation of miRNA metabolic process / DEAD/H-box RNA helicase binding / primary miRNA binding / regulation of regulatory T cell differentiation / ribonuclease III / miRNA metabolic process / primary miRNA processing / ribonuclease III activity / microprocessor complex / pre-miRNA processing ...regulation of miRNA metabolic process / DEAD/H-box RNA helicase binding / primary miRNA binding / regulation of regulatory T cell differentiation / ribonuclease III / miRNA metabolic process / primary miRNA processing / ribonuclease III activity / microprocessor complex / pre-miRNA processing / MicroRNA (miRNA) biogenesis / SMAD binding / R-SMAD binding / lipopolysaccharide binding / rRNA processing / regulation of inflammatory response / defense response to Gram-negative bacterium / postsynaptic density / defense response to Gram-positive bacterium / glutamatergic synapse / positive regulation of gene expression / nucleolus / protein homodimerization activity / RNA binding / nucleoplasm / nucleus / metal ion binding / cytosol類似検索 - 分子機能 RNase III, double-stranded RNA binding domain, animal / Ribonuclease-III-like / Ribonuclease III / Ribonuclease III family signature. / Ribonuclease III domain / Ribonuclease III family domain profile. / Ribonuclease III family / Ribonuclease III domain / Double Stranded RNA Binding Domain - #20 / Double-stranded RNA binding motif ...RNase III, double-stranded RNA binding domain, animal / Ribonuclease-III-like / Ribonuclease III / Ribonuclease III family signature. / Ribonuclease III domain / Ribonuclease III family domain profile. / Ribonuclease III family / Ribonuclease III domain / Double Stranded RNA Binding Domain - #20 / Double-stranded RNA binding motif / Double-stranded RNA binding motif / Ribonuclease III, endonuclease domain superfamily / Double stranded RNA-binding domain (dsRBD) profile. / Double-stranded RNA-binding domain / Double Stranded RNA Binding Domain / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / DGSA-distance geometry simulated annealing |
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Model details | lowest energy, model1 |
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データ登録者 | Showalter, S.A. / Sahu, D. / Kranick, J.C. |
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引用 | ジャーナル: To be Published タイトル: Towards understanding Drosha dsRBDs role in Microprocessing 著者: Showalter, S.A. / Sahu, D. / Kranick, J.C. / Ghosh, D. |
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履歴 | 登録 | 2015年12月17日 | 登録サイト: BMRB / 処理サイト: RCSB |
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改定 1.0 | 2016年12月21日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2023年6月14日 | Group: Data collection / Database references / Other カテゴリ: database_2 / pdbx_database_status ...database_2 / pdbx_database_status / pdbx_nmr_software / pdbx_nmr_spectrometer / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_database_status.status_code_nmr_data / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
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改定 1.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 / Item: _database_2.pdbx_DOI |
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