- PDB-2n8r: Productive complex between MMP-12 and synthetic triple-helical co... -
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基本情報
登録情報
データベース: PDB / ID: 2n8r
タイトル
Productive complex between MMP-12 and synthetic triple-helical collagen, revealed through paramagnetic NMR
要素
Collagen triple helix repeat family protein
Macrophage metalloelastase
キーワード
HYDROLASE/STRUCTURAL PROTEIN / Collagenolysis / matrix petalloproteinase / HYDROLASE-STRUCTURAL PROTEIN complex
機能・相同性
機能・相同性情報
macrophage elastase / negative regulation of endothelial cell-matrix adhesion via fibronectin / bronchiole development / positive regulation of epithelial cell proliferation involved in wound healing / elastin catabolic process / regulation of defense response to virus by host / positive regulation of type I interferon-mediated signaling pathway / wound healing, spreading of epidermal cells / negative regulation of type I interferon-mediated signaling pathway / lung alveolus development ...macrophage elastase / negative regulation of endothelial cell-matrix adhesion via fibronectin / bronchiole development / positive regulation of epithelial cell proliferation involved in wound healing / elastin catabolic process / regulation of defense response to virus by host / positive regulation of type I interferon-mediated signaling pathway / wound healing, spreading of epidermal cells / negative regulation of type I interferon-mediated signaling pathway / lung alveolus development / response to amyloid-beta / Collagen degradation / collagen catabolic process / extracellular matrix disassembly / positive regulation of interferon-alpha production / core promoter sequence-specific DNA binding / collagen binding / Degradation of the extracellular matrix / extracellular matrix organization / extracellular matrix / cellular response to virus / metalloendopeptidase activity / protein import into nucleus / endopeptidase activity / sequence-specific DNA binding / serine-type endopeptidase activity / calcium ion binding / negative regulation of transcription by RNA polymerase II / positive regulation of transcription by RNA polymerase II / proteolysis / extracellular space / zinc ion binding / extracellular region / nucleus / cytoplasm 類似検索 - 分子機能
#1: ジャーナル: J.Biomol.Nmr / 年: 2006 タイトル: 1H, 13C, and 15N peak assignments and secondary structure of human macrophage metalloelastase (MMP-12) in its inhibitor-free state. 著者: Bhaskaran, R. / Van Doren, S.R.
A: Macrophage metalloelastase B: Collagen triple helix repeat family protein C: Collagen triple helix repeat family protein D: Collagen triple helix repeat family protein ヘテロ分子