+Open data
-Basic information
Entry | Database: PDB / ID: 2mev | ||||||||||||
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Title | STRUCTURAL REFINEMENT AND ANALYSIS OF MENGO VIRUS | ||||||||||||
Components | (MENGO VIRUS COAT PROTEIN (SUBUNIT ...) x 4 | ||||||||||||
Keywords | VIRUS / CARDIO PICORNAVIRUS COAT PROTEIN / Icosahedral virus | ||||||||||||
Function / homology | Function and homology information positive stranded viral RNA replication / host cell nucleolus / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity / picornain 3C / T=pseudo3 icosahedral viral capsid / host cell cytoplasmic vesicle membrane / symbiont-mediated suppression of host gene expression / protein complex oligomerization / monoatomic ion channel activity / RNA helicase activity ...positive stranded viral RNA replication / host cell nucleolus / symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of RIG-I activity / picornain 3C / T=pseudo3 icosahedral viral capsid / host cell cytoplasmic vesicle membrane / symbiont-mediated suppression of host gene expression / protein complex oligomerization / monoatomic ion channel activity / RNA helicase activity / RNA helicase / symbiont entry into host cell / induction by virus of host autophagy / cysteine-type endopeptidase activity / RNA-directed RNA polymerase / virus-mediated perturbation of host defense response / RNA-dependent RNA polymerase activity / DNA-templated transcription / virion attachment to host cell / structural molecule activity / ATP hydrolysis activity / proteolysis / RNA binding / ATP binding / membrane / metal ion binding Similarity search - Function | ||||||||||||
Biological species | Mengo virus | ||||||||||||
Method | X-RAY DIFFRACTION / Resolution: 3 Å | ||||||||||||
Authors | Rossmann, M.G. | ||||||||||||
Citation | Journal: J.Mol.Biol. / Year: 1990 Title: Structural refinement and analysis of Mengo virus. Authors: Krishnaswamy, S. / Rossmann, M.G. #1: Journal: Science / Year: 1987 Title: The Atomic Structure of Mengo Virus at 3.0 Angstroms Resolution Authors: Luo, M. / Vriend, G. / Kamer, G. / Minor, I. / Arnold, E. / Rossmann, M.G. / Boege, U. / Scraba, D.G. / Duke, G.M. / Palmenberg, A.C. #2: Journal: Proc.Natl.Acad.Sci.USA / Year: 1987 Title: Implications of the Picornavirus Capsid Structure for Polyprotein Processing Authors: Arnold, E. / Luo, M. / Vriend, G. / Rossmann, M.G. / Palmenberg, A.C. / Parks, G.D. / Nicklin, M.J.H. / Wimmer, E. #3: Journal: Chem.Scr. / Year: 1986 Title: The Structure of a Human Common Cold Virus (Rhinovirus 14) and its Evolutionary Relations to Other Viruses Authors: Rossmann, M.G. / Arnold, E. / Erickson, J.W. / Frankenberger, E.A. / Griffith, J.P. / Hecht, H.-J. / Johnson, J.E. / Kamer, G. / Luo, M. / Vriend, G. / Mosser, A.G. / Palmenberg, A.C. / ...Authors: Rossmann, M.G. / Arnold, E. / Erickson, J.W. / Frankenberger, E.A. / Griffith, J.P. / Hecht, H.-J. / Johnson, J.E. / Kamer, G. / Luo, M. / Vriend, G. / Mosser, A.G. / Palmenberg, A.C. / Rueckert, R.R. / Sherry, B. #4: Journal: Nature / Year: 1985 Title: Structure of a Human Common Cold Virus and Functional Relationship to Other Picornaviruses Authors: Rossmann, M.G. / Arnold, E. / Erickson, J.W. / Frankenberger, E.A. / Griffith, J.P. / Hecht, H.-J. / Johnson, J.E. / Kamer, G. / Luo, M. / Mosser, A.G. / Rueckert, R.R. / Sherry, B. / Vriend, G. #5: Journal: J.Mol.Biol. / Year: 1984 Title: Picornaviruses of Two Different Genera Have Similar Structures Authors: Luo, M. / Arnold, E. / Erickson, J.W. / Rossmann, M.G. / Boege, U. / Scraba, D.G. | ||||||||||||
History |
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Remark 700 |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|
-Structure visualization
Structure viewer | Molecule: MolmilJmol/JSmol |
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-Downloads & links
-Download
PDBx/mmCIF format | 2mev.cif.gz | 181.9 KB | Display | PDBx/mmCIF format |
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PDB format | pdb2mev.ent.gz | 143.4 KB | Display | PDB format |
PDBx/mmJSON format | 2mev.json.gz | Tree view | PDBx/mmJSON format | |
Others | Other downloads |
-Validation report
Summary document | 2mev_validation.pdf.gz | 479.4 KB | Display | wwPDB validaton report |
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Full document | 2mev_full_validation.pdf.gz | 552.3 KB | Display | |
Data in XML | 2mev_validation.xml.gz | 41 KB | Display | |
Data in CIF | 2mev_validation.cif.gz | 55.7 KB | Display | |
Arichive directory | https://data.pdbj.org/pub/pdb/validation_reports/me/2mev ftp://data.pdbj.org/pub/pdb/validation_reports/me/2mev | HTTPS FTP |
-Related structure data
Similar structure data |
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-Links
-Assembly
Deposited unit |
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2 |
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4 |
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5 |
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6 |
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Unit cell |
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Atom site foot note | 1: RESIDUES PRO 1 105, PRO 2 85, PRO 2 152, PRO 3 59 ARE CIS PROLINES. 2: SEE REMARK 9. / 3: SEE REMARK 10. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Symmetry | Point symmetry: (Hermann–Mauguin notation: 532 / Schoenflies symbol: I (icosahedral)) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Noncrystallographic symmetry (NCS) | NCS oper:
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