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- PDB-2m1g: Parallel human telomeric quadruplex containing 2'F-ANA substitutions -
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Basic information
Entry | Database: PDB / ID: 2m1g | ||||||||||||||||||||
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Title | Parallel human telomeric quadruplex containing 2'F-ANA substitutions | ||||||||||||||||||||
![]() | 5'-D(*![]() DNA / parallel G-quadruplex / human telomeric sequence / fluoro-arabinose / molecular interactions | Function / homology | DNA / DNA (> 10) | ![]() Method | SOLUTION NMR / molecular dynamics, simulated annealing | Model details | closest to the average | ![]() Martin-Pintado, N. / Yahyaee-Anzahaee, M. / Deleavey, G.F. / Portella, G. / Orozco, M. / Damha, M.J. / Gonzalez, C. | ![]() ![]() Title: Dramatic effect of furanose c2' substitution on structure and stability: directing the folding of the human telomeric quadruplex with a single fluorine atom. Authors: Martin-Pintado, N. / Yahyaee-Anzahaee, M. / Deleavey, G.F. / Portella, G. / Orozco, M. / Damha, M.J. / Gonzalez, C. History |
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Structure visualization
Structure viewer | Molecule: ![]() ![]() |
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Downloads & links
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PDBx/mmCIF format | ![]() | 158.1 KB | Display | ![]() |
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PDB format | ![]() | 127.9 KB | Display | ![]() |
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-Validation report
Arichive directory | ![]() ![]() | HTTPS FTP |
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-Related structure data
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Links
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Assembly
Deposited unit | ![]()
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NMR ensembles |
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Components
#1: DNA chain | Mass: 3791.453 Da / Num. of mol.: 2 / Source method: obtained synthetically |
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-Experimental details
-Experiment
Experiment | Method: SOLUTION NMR | ||||||||||||||||||||
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NMR experiment |
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Sample preparation
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Sample |
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Sample conditions | Ionic strength: 15 / pH: 7 / Pressure: ambient / Temperature: 278 K |
-NMR measurement
NMR spectrometer |
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Processing
NMR software |
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Refinement | Method: molecular dynamics, simulated annealing / Software ordinal: 1 | |||||||||||||||||||||
NMR representative | Selection criteria: closest to the average | |||||||||||||||||||||
NMR ensemble | Conformer selection criteria: structures with the lowest energy Conformers calculated total number: 20 / Conformers submitted total number: 10 |