登録情報 | データベース: PDB / ID: 2kmd |
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タイトル | Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to co-activator CBP |
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要素 | Protein C-ets-1 |
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キーワード | TRANSCRIPTION / PROTEIN BINDING / PNT DOMAIN / SAM DOMAIN / ETS-1 / MAPK PHOSPHORYLATION / PHOSPHOPROTEIN / PROTO-ONCOGENE / TRANSCRIPTION REGULATION / CONFORMATIONAL DYNAMICS |
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機能・相同性 | 機能・相同性情報
Oncogene Induced Senescence / regulation of extracellular matrix disassembly / histone acetyltransferase binding / immune system process / regulation of angiogenesis / positive regulation of endothelial cell migration / positive regulation of erythrocyte differentiation / negative regulation of inflammatory response / positive regulation of angiogenesis / sequence-specific double-stranded DNA binding ...Oncogene Induced Senescence / regulation of extracellular matrix disassembly / histone acetyltransferase binding / immune system process / regulation of angiogenesis / positive regulation of endothelial cell migration / positive regulation of erythrocyte differentiation / negative regulation of inflammatory response / positive regulation of angiogenesis / sequence-specific double-stranded DNA binding / DNA-binding transcription factor binding / transcription regulator complex / sequence-specific DNA binding / nucleic acid binding / DNA-binding transcription factor activity, RNA polymerase II-specific / positive regulation of cell migration / DNA-binding transcription factor activity / positive regulation of cell population proliferation / regulation of transcription by RNA polymerase II / positive regulation of DNA-templated transcription / positive regulation of transcription by RNA polymerase II / DNA binding / nucleus / cytoplasm類似検索 - 分子機能 Protein C-ets-1, pointed domain / Transforming protein C-ets / Ets1, N-terminal flanking region of Ets domain / Ets1 N-terminal flanking region of Ets domain / SAM / Pointed domain / Pointed domain / Sterile alpha motif (SAM)/Pointed domain / Pointed (PNT) domain profile. / Transcription Factor, Ets-1 / Ets-domain signature 1. ...Protein C-ets-1, pointed domain / Transforming protein C-ets / Ets1, N-terminal flanking region of Ets domain / Ets1 N-terminal flanking region of Ets domain / SAM / Pointed domain / Pointed domain / Sterile alpha motif (SAM)/Pointed domain / Pointed (PNT) domain profile. / Transcription Factor, Ets-1 / Ets-domain signature 1. / ETS family / Ets-domain signature 2. / Ets domain / Ets-domain / Ets-domain profile. / erythroblast transformation specific domain / Sterile alpha motif/pointed domain superfamily / DNA polymerase; domain 1 / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Mus musculus (ハツカネズミ) |
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手法 | 溶液NMR / simulated annealing |
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データ登録者 | Nelson, M.L. / Kang, H. / Lee, G.M. / Blaszczak, A.G. / Lau, D.K.W. / McIntosh, L.P. / Graves, B.J. |
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引用 | ジャーナル: Proc.Natl.Acad.Sci.USA / 年: 2010 タイトル: Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP. 著者: Nelson, M.L. / Kang, H.S. / Lee, G.M. / Blaszczak, A.G. / Lau, D.K. / McIntosh, L.P. / Graves, B.J. |
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履歴 | 登録 | 2009年7月27日 | 登録サイト: BMRB / 処理サイト: RCSB |
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改定 1.0 | 2010年5月5日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年7月13日 | Group: Version format compliance |
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改定 1.2 | 2012年3月21日 | Group: Database references |
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