登録情報 | データベース: PDB / ID: 2j76 |
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タイトル | Solution structure and RNA interactions of the RNA recognition motif from eukaryotic translation initiation factor 4B |
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要素 | EUKARYOTIC TRANSLATION INITIATION FACTOR 4B |
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キーワード | TRANSLATION / PROTEIN BIOSYNTHESIS / RNA RECOGNITION MOTIF / INITIATION FACTOR / RNA BINDING DOMAIN / RRM / RBD / RNP / RNA-BINDING / PHOSPHORYLATION |
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機能・相同性 | 機能・相同性情報
eukaryotic translation initiation factor 4F complex assembly / RNA strand-exchange activity / Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S / RNA strand annealing activity / eukaryotic translation initiation factor 4F complex / Z-decay: degradation of maternal mRNAs by zygotically expressed factors / formation of translation preinitiation complex / Deadenylation of mRNA / M-decay: degradation of maternal mRNAs by maternally stored factors / regulation of translational initiation ...eukaryotic translation initiation factor 4F complex assembly / RNA strand-exchange activity / Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S / RNA strand annealing activity / eukaryotic translation initiation factor 4F complex / Z-decay: degradation of maternal mRNAs by zygotically expressed factors / formation of translation preinitiation complex / Deadenylation of mRNA / M-decay: degradation of maternal mRNAs by maternally stored factors / regulation of translational initiation / Ribosomal scanning and start codon recognition / Translation initiation complex formation / mTORC1-mediated signalling / ribosomal small subunit binding / GTP hydrolysis and joining of the 60S ribosomal subunit / L13a-mediated translational silencing of Ceruloplasmin expression / translation initiation factor activity / RNA binding / cytosol類似検索 - 分子機能 Eukaryotic translation initiation factor 4B / RRM (RNA recognition motif) domain / RNA recognition motif / RNA recognition motif / Eukaryotic RNA Recognition Motif (RRM) profile. / RNA recognition motif domain / RNA-binding domain superfamily / Nucleotide-binding alpha-beta plait domain superfamily / Alpha-Beta Plaits / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | HOMO SAPIENS (ヒト) |
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手法 | 溶液NMR |
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Model type details | MINIMIZED AVERAGE |
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データ登録者 | Fleming, K. / Ghuman, J. / Yuan, X.M. / Simpson, P. / Szendroi, A. / Matthews, S. / Curry, S. |
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引用 | ジャーナル: Biochemistry / 年: 2003 タイトル: Solution Structure and RNA Interactions of the RNA Recognition Motif from Eukaryotic Translation Initiation Factor 4B. 著者: Fleming, K. / Ghuman, J. / Yuan, X.M. / Simpson, P. / Szendroi, A. / Matthews, S. / Curry, S. |
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履歴 | 登録 | 2006年10月6日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2008年10月28日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2017年4月19日 | Group: Other |
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改定 1.2 | 2024年5月15日 | Group: Data collection / Database references / カテゴリ: chem_comp_atom / chem_comp_bond / database_2 Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession |
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