登録情報 | データベース: PDB / ID: 2j5h |
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タイトル | NMR analysis of mouse CRIPTO CFC domain |
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要素 | TERATOCARCINOMA-DERIVED GROWTH FACTOR |
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キーワード | HORMONE/GROWTH FACTOR / GROWTH FACTOR / EGF-CFC FAMILY / CRIPTO / TUMOUR PROGRESSION / CYSTEINE-RICH DOMAINS / HORMONE-GROWTH FACTOR COMPLEX |
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機能・相同性 | 機能・相同性情報
type I activin receptor binding / nodal binding / : / morphogenesis of a branching structure / nodal signaling pathway / anatomical structure development / : / anterior/posterior axis specification, embryo / activin receptor binding / Wnt-protein binding ...type I activin receptor binding / nodal binding / : / morphogenesis of a branching structure / nodal signaling pathway / anatomical structure development / : / anterior/posterior axis specification, embryo / activin receptor binding / Wnt-protein binding / cardiac muscle cell differentiation / cellular response to interleukin-6 / cellular response to fibroblast growth factor stimulus / cell migration involved in sprouting angiogenesis / determination of left/right symmetry / anterior/posterior axis specification / anterior/posterior pattern specification / positive regulation of cell-matrix adhesion / cellular response to hepatocyte growth factor stimulus / extrinsic component of plasma membrane / blood vessel development / regulation of signal transduction / vasculogenesis / coreceptor activity / gastrulation / regulation of cell migration / cellular response to epidermal growth factor stimulus / positive regulation of endothelial cell migration / negative regulation of transforming growth factor beta receptor signaling pathway / growth factor activity / cellular response to type II interferon / positive regulation of peptidyl-tyrosine phosphorylation / positive regulation of fibroblast proliferation / cellular response to tumor necrosis factor / heart development / peptidyl-serine phosphorylation / in utero embryonic development / cell differentiation / positive regulation of cell migration / membrane raft / apical plasma membrane / signaling receptor binding / positive regulation of cell population proliferation / negative regulation of apoptotic process / perinuclear region of cytoplasm / Golgi apparatus / cell surface / positive regulation of transcription by RNA polymerase II / extracellular space / extracellular region / nucleus / plasma membrane / cytoplasm類似検索 - 分子機能 Teratocarcinoma-derived growth factor Cripto / Cryptic/Cripto, CFC domain / Cripto_Frl-1_Cryptic (CFC) / EGF-like domain profile. / EGF-like domain signature 1. / EGF-like domain類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) MUS MUSCULUS (ハツカネズミ) |
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手法 | 溶液NMR |
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データ登録者 | Calvanese, L. / Saporito, A. / Marasco, D. / D'Auria, G. / Minchiotti, G. / Pedone, C. / Paolillo, L. / Falcigno, L. / Ruvo, M. |
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引用 | ジャーナル: J. Med. Chem. / 年: 2006 タイトル: Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala. 著者: Calvanese, L. / Saporito, A. / Marasco, D. / D'Auria, G. / Minchiotti, G. / Pedone, C. / Paolillo, L. / Falcigno, L. / Ruvo, M. |
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履歴 | 登録 | 2006年9月18日 | 登録サイト: PDBE / 処理サイト: PDBE |
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改定 1.0 | 2006年10月2日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2011年5月8日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2018年5月9日 | Group: Data collection / Database references / カテゴリ: citation / pdbx_nmr_spectrometer Item: _citation.journal_abbrev / _citation.page_last ..._citation.journal_abbrev / _citation.page_last / _citation.pdbx_database_id_DOI / _citation.title / _pdbx_nmr_spectrometer.model |
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