negative regulation of membrane potential / negative regulation of mitochondrial membrane permeability involved in apoptotic process / granzyme-mediated programmed cell death signaling pathway / cellular response to cobalt ion / mitochondrial outer membrane permeabilization / response to oxygen-glucose deprivation / positive regulation of mitochondrial calcium ion concentration / autophagic cell death / negative regulation of mitochondrial fusion / positive regulation of autophagy of mitochondrion ...negative regulation of membrane potential / negative regulation of mitochondrial membrane permeability involved in apoptotic process / granzyme-mediated programmed cell death signaling pathway / cellular response to cobalt ion / mitochondrial outer membrane permeabilization / response to oxygen-glucose deprivation / positive regulation of mitochondrial calcium ion concentration / autophagic cell death / negative regulation of mitochondrial fusion / positive regulation of autophagy of mitochondrion / mitochondrial fragmentation involved in apoptotic process / autophagy of mitochondrion / mitochondrial protein catabolic process / positive regulation of programmed cell death / positive regulation of protein-containing complex disassembly / negative regulation of programmed cell death / intrinsic apoptotic signaling pathway in response to hypoxia / regulation of mitochondrial membrane permeability / regulation of aerobic respiration / positive regulation of mitochondrial fission / positive regulation of cardiac muscle cell apoptotic process / oligodendrocyte differentiation / positive regulation of release of cytochrome c from mitochondria / negative regulation of mitochondrial membrane potential / positive regulation of macroautophagy / negative regulation of reactive oxygen species metabolic process / response to axon injury / response to hyperoxia / positive regulation of autophagy / brown fat cell differentiation / cardiac muscle cell apoptotic process / reactive oxygen species metabolic process / response to bacterium / cellular response to mechanical stimulus / mitochondrial membrane / cerebral cortex development / cellular response to hydrogen peroxide / nuclear envelope / GTPase binding / cellular response to hypoxia / neuron apoptotic process / defense response to virus / mitochondrial outer membrane / postsynaptic density / response to hypoxia / positive regulation of apoptotic process / dendrite / negative regulation of apoptotic process / endoplasmic reticulum / protein homodimerization activity / mitochondrion / nucleoplasm / identical protein binding / nucleus / cytoplasm Similarity search - Function
Single alpha-helices involved in coiled-coils or other helix-helix interfaces - #1020 / BNIP3 / BNIP3 / Single alpha-helices involved in coiled-coils or other helix-helix interfaces / Helix non-globular / Special Similarity search - Domain/homology
Method: TAD / Software ordinal: 1 Details: NMR-DERIVED STRUCTURES OF BNIP3 TM DIMERIC WERE RELAXATED BY MOLECULAR DYNAMICS IN EXPLICIT LIPID DMPC BILAYER USING NMR CONSTRAINTS THERE ARE SLOW CONFORMATIONAL EXCHANGE IN HYDROGEN BOND ...Details: NMR-DERIVED STRUCTURES OF BNIP3 TM DIMERIC WERE RELAXATED BY MOLECULAR DYNAMICS IN EXPLICIT LIPID DMPC BILAYER USING NMR CONSTRAINTS THERE ARE SLOW CONFORMATIONAL EXCHANGE IN HYDROGEN BOND NET OF (SER172, HIS173)2 CLUSTER ON THE DIMERIZATION INTERFACE.
NMR ensemble
Conformer selection criteria: THE BEST TARGET FUNCTION / Conformers calculated total number: 200 / Conformers submitted total number: 16
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