- PDB-2il1: Crystal structure of a predicted human GTPase in complex with GDP -
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Basic information
Entry
Database: PDB / ID: 2il1
Title
Crystal structure of a predicted human GTPase in complex with GDP
Components
Rab12
Keywords
PROTEIN TRANSPORT / G-PROTEIN / RAB / GDP / GTPASE / PREDICTED / Structural Genomics / Structural Genomics Consortium / SGC
Function / homology
Function and homology information
retrograde transport, plasma membrane to Golgi / protein catabolic process => GO:0030163 / Rab protein signal transduction / phagosome maturation / Retrograde transport at the Trans-Golgi-Network / insulin-responsive compartment / RAB geranylgeranylation / vesicle docking involved in exocytosis / regulation of exocytosis / RAB GEFs exchange GTP for GDP on RABs ...retrograde transport, plasma membrane to Golgi / protein catabolic process => GO:0030163 / Rab protein signal transduction / phagosome maturation / Retrograde transport at the Trans-Golgi-Network / insulin-responsive compartment / RAB geranylgeranylation / vesicle docking involved in exocytosis / regulation of exocytosis / RAB GEFs exchange GTP for GDP on RABs / virion assembly / endosome to lysosome transport / Golgi organization / positive regulation of macroautophagy / autophagosome assembly / protein secretion / autophagosome / endomembrane system / phagocytic vesicle / trans-Golgi network membrane / protein localization to plasma membrane / intracellular protein transport / recycling endosome / autophagy / cellular response to type II interferon / cellular response to insulin stimulus / recycling endosome membrane / phagocytic vesicle membrane / GDP binding / synaptic vesicle / lysosome / endosome / lysosomal membrane / Golgi membrane / GTPase activity / GTP binding / Golgi apparatus / extracellular exosome / plasma membrane / cytosol Similarity search - Function
Rab12 / : / small GTPase Rab1 family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / Small GTPase / Ras family / Rab subfamily of small GTPases / Small GTP-binding protein domain ...Rab12 / : / small GTPase Rab1 family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / Small GTPase / Ras family / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase / Rossmann fold / 3-Layer(aba) Sandwich / Alpha Beta Similarity search - Domain/homology
BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 1 CHAIN(S) ...BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 1 CHAIN(S). THE BIOLOGICAL UNIT OF THE PROTEIN IS NOT KNOWN
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