- PDB-2il1: Crystal structure of a predicted human GTPase in complex with GDP -
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基本情報
登録情報
データベース: PDB / ID: 2il1
タイトル
Crystal structure of a predicted human GTPase in complex with GDP
要素
Rab12
キーワード
PROTEIN TRANSPORT / G-PROTEIN (Gタンパク質) / RAB / GDP / GTPASE (GTPアーゼ) / PREDICTED (予想) / Structural Genomics (構造ゲノミクス) / Structural Genomics Consortium / SGC
機能・相同性
機能・相同性情報
retrograde transport, plasma membrane to Golgi / protein catabolic process => GO:0030163 / Rab protein signal transduction / phagosome maturation / Retrograde transport at the Trans-Golgi-Network / insulin-responsive compartment / RAB geranylgeranylation / vesicle docking involved in exocytosis / regulation of exocytosis / RAB GEFs exchange GTP for GDP on RABs ...retrograde transport, plasma membrane to Golgi / protein catabolic process => GO:0030163 / Rab protein signal transduction / phagosome maturation / Retrograde transport at the Trans-Golgi-Network / insulin-responsive compartment / RAB geranylgeranylation / vesicle docking involved in exocytosis / regulation of exocytosis / RAB GEFs exchange GTP for GDP on RABs / endosome to lysosome transport / virion assembly / Golgi organization / autophagosome assembly / positive regulation of macroautophagy / protein secretion / オートファゴソーム / 細胞内膜系 / phagocytic vesicle / trans-Golgi network membrane / protein localization to plasma membrane / intracellular protein transport / recycling endosome / オートファジー / cellular response to type II interferon / cellular response to insulin stimulus / recycling endosome membrane / phagocytic vesicle membrane / GDP binding / シナプス小胞 / リソソーム / エンドソーム / lysosomal membrane / ゴルジ体 / GTPase activity / GTP binding / ゴルジ体 / extracellular exosome / 細胞膜 / 細胞質基質 類似検索 - 分子機能
Rab12 / : / small GTPase Rab1 family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / 低分子量GTPアーゼ / 低分子量GTPアーゼ / Rab subfamily of small GTPases / Small GTP-binding protein domain ...Rab12 / : / small GTPase Rab1 family profile. / Ran (Ras-related nuclear proteins) /TC4 subfamily of small GTPases / Rho (Ras homology) subfamily of Ras-like small GTPases / Ras subfamily of RAS small GTPases / 低分子量GTPアーゼ / 低分子量GTPアーゼ / Rab subfamily of small GTPases / Small GTP-binding protein domain / P-loop containing nucleotide triphosphate hydrolases / P-loop containing nucleoside triphosphate hydrolase / ロスマンフォールド / 3-Layer(aba) Sandwich / Alpha Beta 類似検索 - ドメイン・相同性
GUANOSINE-5'-DIPHOSPHATE / Ras-related protein Rab-12 / Ras-related protein Rab-43 類似検索 - 構成要素
BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 1 CHAIN(S) ...BIOMOLECULE: 1 THIS ENTRY CONTAINS THE CRYSTALLOGRAPHIC ASYMMETRIC UNIT WHICH CONSISTS OF 1 CHAIN(S). THE BIOLOGICAL UNIT OF THE PROTEIN IS NOT KNOWN