登録情報 | データベース: PDB / ID: 2hh3 |
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タイトル | Solution structure of the third KH domain of KSRP |
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要素 | KH-type splicing regulatory protein |
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キーワード | RNA BINDING PROTEIN / KH-RNA binding domain |
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機能・相同性 | 機能・相同性情報
positive regulation of mRNA catabolic process / negative regulation of low-density lipoprotein particle clearance / ATF4 activates genes in response to endoplasmic reticulum stress / miRNA metabolic process / 3'-UTR-mediated mRNA destabilization / negative regulation of nitric oxide biosynthetic process / mRNA 3'-UTR AU-rich region binding / RNA splicing, via transesterification reactions / KSRP (KHSRP) binds and destabilizes mRNA / regulation of alternative mRNA splicing, via spliceosome ...positive regulation of mRNA catabolic process / negative regulation of low-density lipoprotein particle clearance / ATF4 activates genes in response to endoplasmic reticulum stress / miRNA metabolic process / 3'-UTR-mediated mRNA destabilization / negative regulation of nitric oxide biosynthetic process / mRNA 3'-UTR AU-rich region binding / RNA splicing, via transesterification reactions / KSRP (KHSRP) binds and destabilizes mRNA / regulation of alternative mRNA splicing, via spliceosome / cellular response to cytokine stimulus / mRNA transport / protein folding chaperone / regulation of mRNA stability / RNA splicing / mRNA processing / regulation of gene expression / mRNA binding / regulation of DNA-templated transcription / DNA binding / RNA binding / nucleoplasm / membrane / nucleus / cytoplasm / cytosol類似検索 - 分子機能 : / : / : / : / Far upstream element-binding protein, C-terminal / Domain of unknown function (DUF1897) / K Homology domain, type 1 / KH domain / K Homology domain, type 1 / Ribosomal Protein S8; Chain: A, domain 1 ...: / : / : / : / Far upstream element-binding protein, C-terminal / Domain of unknown function (DUF1897) / K Homology domain, type 1 / KH domain / K Homology domain, type 1 / Ribosomal Protein S8; Chain: A, domain 1 / Type-1 KH domain profile. / K Homology domain, type 1 superfamily / K Homology domain / K homology RNA-binding domain / 2-Layer Sandwich / Alpha Beta類似検索 - ドメイン・相同性 Far upstream element-binding protein 2 / Far upstream element-binding protein 2類似検索 - 構成要素 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Garcia-Mayoral, M.F. |
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引用 | ジャーナル: Structure / 年: 2007 タイトル: The Structure of the C-Terminal KH Domains of KSRP Reveals a Noncanonical Motif Important for mRNA Degradation. 著者: Garcia-Mayoral, M.F. / Hollingworth, D. / Masino, L. / Diaz-Moreno, I. / Kelly, G. / Gherzi, R. / Chou, C.F. / Chen, C.Y. / Ramos, A. |
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履歴 | 登録 | 2006年6月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2007年5月8日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月9日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_software ...database_2 / pdbx_nmr_software / pdbx_nmr_spectrometer / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _pdbx_nmr_spectrometer.model / _struct_ref_seq_dif.details |
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改定 1.4 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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