登録情報 | データベース: PDB / ID: 2hh0 |
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タイトル | Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope. |
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要素 | - Heavy Chain, P-Clone Fab, Chimera
- Light Chain, P-Clone Fab, Chimera
- Prion protein
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キーワード | IMMUNE SYSTEM / prion / prp / fab |
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機能・相同性 | 機能・相同性情報
: / type 5 metabotropic glutamate receptor binding / cuprous ion binding / side of membrane / inclusion body / cellular response to copper ion / molecular condensate scaffold activity / protein destabilization / protein homooligomerization / cellular response to amyloid-beta ...: / type 5 metabotropic glutamate receptor binding / cuprous ion binding / side of membrane / inclusion body / cellular response to copper ion / molecular condensate scaffold activity / protein destabilization / protein homooligomerization / cellular response to amyloid-beta / positive regulation of peptidyl-tyrosine phosphorylation / positive regulation of neuron apoptotic process / amyloid-beta binding / G-quadruplex RNA binding / microtubule binding / nuclear membrane / membrane raft / copper ion binding / dendrite / protein-containing complex binding / Golgi apparatus / cell surface / identical protein binding / plasma membrane / cytosol類似検索 - 分子機能 Prion protein signature 1. / Prion protein signature 2. / Major prion protein N-terminal domain / Major prion protein bPrPp - N terminal / Prion protein / Major prion protein / Prion/Doppel protein, beta-ribbon domain / Prion/Doppel beta-ribbon domain superfamily / Prion/Doppel alpha-helical domain / Immunoglobulins ...Prion protein signature 1. / Prion protein signature 2. / Major prion protein N-terminal domain / Major prion protein bPrPp - N terminal / Prion protein / Major prion protein / Prion/Doppel protein, beta-ribbon domain / Prion/Doppel beta-ribbon domain superfamily / Prion/Doppel alpha-helical domain / Immunoglobulins / Immunoglobulin-like / Sandwich / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | ![](img/tx_mammal.gif) Mus musculus (ハツカネズミ)
Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / フーリエ合成 / 解像度: 2.85 Å |
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データ登録者 | Kanyo, Z.K. |
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引用 | #1: ジャーナル: Nat.Biotechnol. / 年: 2002タイトル: Measuring Prions Causing Bovine Spongiform Encephalopathy or Chronic Wasting Disease by Immunoassays and Transgenic Mice. 著者: Safar, J.G. / Scott, M. / Monaghan, J. / Deering, C. / Didorenko, S. / Vergara, J. / Ball, H. / Legname, G. / Leclerc, E. / Solforosi, L. / Serban, H. / Groth, D. / Burton, D.R. / Prusiner, S. ...著者: Safar, J.G. / Scott, M. / Monaghan, J. / Deering, C. / Didorenko, S. / Vergara, J. / Ball, H. / Legname, G. / Leclerc, E. / Solforosi, L. / Serban, H. / Groth, D. / Burton, D.R. / Prusiner, S.B. / Williamson, R.A. |
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履歴 | 登録 | 2006年6月27日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2006年12月26日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2017年10月11日 | Group: Data collection / Refinement description / カテゴリ: reflns_shell / software Item: _reflns_shell.percent_possible_all / _software.classification |
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