登録情報 | データベース: PDB / ID: 2ga2 |
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タイトル | h-MetAP2 complexed with A193400 |
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要素 | Methionine aminopeptidase 2 |
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キーワード | HYDROLASE / complex |
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機能・相同性 | 機能・相同性情報
N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / methionyl aminopeptidase / metalloexopeptidase activity / metalloaminopeptidase activity / aminopeptidase activity / protein processing / Inactivation, recovery and regulation of the phototransduction cascade / RNA binding ...N-terminal protein amino acid modification / peptidyl-methionine modification / initiator methionyl aminopeptidase activity / methionyl aminopeptidase / metalloexopeptidase activity / metalloaminopeptidase activity / aminopeptidase activity / protein processing / Inactivation, recovery and regulation of the phototransduction cascade / RNA binding / metal ion binding / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 Peptidase M24A, methionine aminopeptidase, subfamily 2 / Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site / Methionine aminopeptidase subfamily 2 signature. / Peptidase M24, methionine aminopeptidase / Creatine Amidinohydrolase / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 / Creatinase/aminopeptidase-like / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain ...Peptidase M24A, methionine aminopeptidase, subfamily 2 / Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site / Methionine aminopeptidase subfamily 2 signature. / Peptidase M24, methionine aminopeptidase / Creatine Amidinohydrolase / Creatinase/methionine aminopeptidase superfamily / Peptidase M24 / Metallopeptidase family M24 / Creatinase/aminopeptidase-like / Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain / Arc Repressor Mutant, subunit A / Winged helix DNA-binding domain superfamily / Winged helix-like DNA-binding domain superfamily / Alpha-Beta Complex / Orthogonal Bundle / Mainly Alpha / Alpha Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / 分子置換 / 解像度: 1.95 Å |
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データ登録者 | Park, C. |
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引用 | ジャーナル: Bioorg.Med.Chem.Lett. / 年: 2006 タイトル: Development of sulfonamide compounds as potent methionine aminopeptidase type II inhibitors with antiproliferative properties. 著者: Kawai, M. / BaMaung, N.Y. / Fidanze, S.D. / Erickson, S.A. / Tedrow, J.S. / Sanders, W.J. / Vasudevan, A. / Park, C. / Hutchins, C. / Comess, K.M. / Kalvin, D. / Wang, J. / Zhang, Q. / Lou, P. ...著者: Kawai, M. / BaMaung, N.Y. / Fidanze, S.D. / Erickson, S.A. / Tedrow, J.S. / Sanders, W.J. / Vasudevan, A. / Park, C. / Hutchins, C. / Comess, K.M. / Kalvin, D. / Wang, J. / Zhang, Q. / Lou, P. / Tucker-Garcia, L. / Bouska, J. / Bell, R.L. / Lesniewski, R. / Henkin, J. / Sheppard, G.S. |
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履歴 | 登録 | 2006年3月7日 | 登録サイト: RCSB / 処理サイト: RCSB |
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改定 1.0 | 2007年3月13日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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