登録情報 | データベース: PDB / ID: 2eyw |
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タイトル | N-terminal SH3 domain of CT10-Regulated Kinase |
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要素 | v-crk sarcoma virus CT10 oncogene homolog isoform a |
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キーワード | SIGNALING PROTEIN / SH3 |
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機能・相同性 | 機能・相同性情報
response to hepatocyte growth factor / regulation of intracellular signal transduction / cellular response to endothelin / helper T cell diapedesis / cerebellar neuron development / response to cholecystokinin / postsynaptic specialization assembly / protein phosphorylated amino acid binding / regulation of T cell migration / reelin-mediated signaling pathway ...response to hepatocyte growth factor / regulation of intracellular signal transduction / cellular response to endothelin / helper T cell diapedesis / cerebellar neuron development / response to cholecystokinin / postsynaptic specialization assembly / protein phosphorylated amino acid binding / regulation of T cell migration / reelin-mediated signaling pathway / regulation of dendrite development / positive regulation of skeletal muscle acetylcholine-gated channel clustering / negative regulation of natural killer cell mediated cytotoxicity / response to yeast / negative regulation of wound healing / regulation of protein binding / negative regulation of cell motility / ARMS-mediated activation / protein localization to membrane / MET receptor recycling / MET activates RAP1 and RAC1 / cellular response to insulin-like growth factor stimulus / establishment of cell polarity / regulation of GTPase activity / p130Cas linkage to MAPK signaling for integrins / positive regulation of smooth muscle cell migration / dendrite development / positive regulation of Rac protein signal transduction / regulation of cell adhesion mediated by integrin / cellular response to nitric oxide / regulation of signal transduction / ephrin receptor signaling pathway / PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases / signaling adaptor activity / positive regulation of substrate adhesion-dependent cell spreading / cellular response to transforming growth factor beta stimulus / cytoskeletal protein binding / ephrin receptor binding / phosphotyrosine residue binding / Downstream signal transduction / SH2 domain binding / protein tyrosine kinase binding / cell chemotaxis / cellular response to nerve growth factor stimulus / Regulation of signaling by CBL / hippocampus development / regulation of actin cytoskeleton organization / positive regulation of JNK cascade / FCGR3A-mediated phagocytosis / insulin-like growth factor receptor binding / neuron migration / response to hydrogen peroxide / neuromuscular junction / lipid metabolic process / receptor tyrosine kinase binding / cerebral cortex development / Regulation of actin dynamics for phagocytic cup formation / kinase binding / VEGFA-VEGFR2 Pathway / SH3 domain binding / : / signaling receptor complex adaptor activity / cell migration / actin cytoskeleton / regulation of cell shape / actin cytoskeleton organization / scaffold protein binding / positive regulation of cell growth / cell population proliferation / ubiquitin protein ligase binding / regulation of transcription by RNA polymerase II / signal transduction / protein-containing complex / extracellular exosome / membrane / nucleus / plasma membrane / cytoplasm / cytosol類似検索 - 分子機能 CRK, N-terminal SH3 domain / CRK, C-terminal SH3 domain / Variant SH3 domain / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH3 type barrels. / SH2 domain ...CRK, N-terminal SH3 domain / CRK, C-terminal SH3 domain / Variant SH3 domain / SH3 Domains / SH3 domain / SH2 domain / Src homology 2 (SH2) domain profile. / Src homology 2 domains / SH3 type barrels. / SH2 domain / Src homology 3 domains / SH2 domain superfamily / SH3-like domain superfamily / Src homology 3 (SH3) domain profile. / SH3 domain / Roll / Mainly Beta類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | 溶液NMR / torsion angle dynamics |
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データ登録者 | Kobashigawa, Y. / Tanaka, S. / Inagaki, F. |
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引用 | ジャーナル: Nat.Struct.Mol.Biol. / 年: 2007 タイトル: Structural basis for the transforming activity of human cancer-related signaling adaptor protein CRK. 著者: Kobashigawa, Y. / Sakai, M. / Naito, M. / Yokochi, M. / Kumeta, H. / Makino, Y. / Ogura, K. / Tanaka, S. / Inagaki, F. |
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履歴 | 登録 | 2005年11月10日 | 登録サイト: RCSB / 処理サイト: PDBJ |
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改定 1.0 | 2006年11月10日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年5月1日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Version format compliance |
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改定 1.3 | 2022年3月9日 | Group: Data collection / Database references / Derived calculations カテゴリ: database_2 / pdbx_nmr_software ...database_2 / pdbx_nmr_software / pdbx_struct_assembly / pdbx_struct_oper_list / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession ..._database_2.pdbx_DOI / _database_2.pdbx_database_accession / _pdbx_nmr_software.name / _struct_ref_seq_dif.details |
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改定 1.4 | 2024年5月29日 | Group: Data collection / カテゴリ: chem_comp_atom / chem_comp_bond |
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