登録情報 | データベース: PDB / ID: 2elb |
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タイトル | Crystal Structure of the BAR-PH domain of human APPL1 |
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要素 | Adapter protein containing PH domain, PTB domain and leucine zipper motif 1 |
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キーワード | PROTEIN BINDING / APPL / BAR domain / PH domain |
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機能・相同性 | 機能・相同性情報
negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis / positive regulation of macropinocytosis / adiponectin-activated signaling pathway / macropinosome / regulation of fibroblast migration / regulation of glucose import / protein kinase B binding / maintenance of synapse structure / signaling / positive regulation of melanin biosynthetic process ...negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis / positive regulation of macropinocytosis / adiponectin-activated signaling pathway / macropinosome / regulation of fibroblast migration / regulation of glucose import / protein kinase B binding / maintenance of synapse structure / signaling / positive regulation of melanin biosynthetic process / regulation of toll-like receptor 4 signaling pathway / early phagosome / positive regulation of cytokine production involved in inflammatory response / Caspase activation via Dependence Receptors in the absence of ligand / vesicle membrane / cellular response to hepatocyte growth factor stimulus / intracellular vesicle / regulation of innate immune response / beta-tubulin binding / phosphatidylserine binding / regulation of G1/S transition of mitotic cell cycle / regulation of protein localization to plasma membrane / ruffle / phosphatidylinositol binding / transforming growth factor beta receptor signaling pathway / positive regulation of glucose import / protein import into nucleus / insulin receptor signaling pathway / presynapse / early endosome membrane / cytoplasmic vesicle / postsynapse / early endosome / endosome membrane / endosome / glutamatergic synapse / protein-containing complex binding / signal transduction / protein homodimerization activity / extracellular exosome / identical protein binding / membrane / nucleus / plasma membrane / cytosol / cytoplasm類似検索 - 分子機能 APPL1, BAR domain / : / : / : / BAR domain of APPL family / Arfaptin homology (AH) domain/BAR domain / BAR domain / Phosphotyrosine interaction domain (PTB/PID) / Phosphotyrosine interaction domain (PID) profile. / Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain ...APPL1, BAR domain / : / : / : / BAR domain of APPL family / Arfaptin homology (AH) domain/BAR domain / BAR domain / Phosphotyrosine interaction domain (PTB/PID) / Phosphotyrosine interaction domain (PID) profile. / Phosphotyrosine-binding domain, phosphotyrosine-interaction (PI) domain / PTB/PI domain / AH/BAR domain superfamily / Substrate Binding Domain Of Dnak; Chain:A; Domain 2 / Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB) / PH-domain like / PH domain / PH domain profile. / Pleckstrin homology domain. / Pleckstrin homology domain / PH-like domain superfamily / Roll / Up-down Bundle / Mainly Beta / Mainly Alpha類似検索 - ドメイン・相同性 |
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生物種 | Homo sapiens (ヒト) |
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手法 | X線回折 / シンクロトロン / 単波長異常分散 / 解像度: 2.6 Å |
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データ登録者 | Li, J. / Mao, X. / Dong, L.Q. / Liu, F. / Tong, L. |
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引用 | ジャーナル: Structure / 年: 2007 タイトル: Crystal Structures of the BAR-PH and PTB Domains of Human APPL1 著者: Li, J. / Mao, X. / Dong, L.Q. / Liu, F. / Tong, L. |
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履歴 | 登録 | 2007年3月27日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
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改定 1.0 | 2007年5月29日 | Provider: repository / タイプ: Initial release |
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改定 1.1 | 2008年4月30日 | Group: Version format compliance |
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改定 1.2 | 2011年7月13日 | Group: Derived calculations / Version format compliance |
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