登録情報 | データベース: PDB / ID: 2dzn |
---|
タイトル | Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3 |
---|
要素 | - 26S protease regulatory subunit 6B homolog
- Probable 26S proteasome regulatory subunit p28
|
---|
キーワード | PROTEIN BINDING / ankyrin repeats / a-helical domain / Structural Genomics / NPPSFA / National Project on Protein Structural and Functional Analyses / RIKEN Structural Genomics/Proteomics Initiative / RSGI |
---|
機能・相同性 | 機能・相同性情報
proteasome regulatory particle binding / proteasome regulatory particle assembly / proteasome-activating activity / proteasome regulatory particle, base subcomplex / Cross-presentation of soluble exogenous antigens (endosomes) / TNFR2 non-canonical NF-kB pathway / Ubiquitin Mediated Degradation of Phosphorylated Cdc25A / Regulation of PTEN stability and activity / KEAP1-NFE2L2 pathway / CDK-mediated phosphorylation and removal of Cdc6 ...proteasome regulatory particle binding / proteasome regulatory particle assembly / proteasome-activating activity / proteasome regulatory particle, base subcomplex / Cross-presentation of soluble exogenous antigens (endosomes) / TNFR2 non-canonical NF-kB pathway / Ubiquitin Mediated Degradation of Phosphorylated Cdc25A / Regulation of PTEN stability and activity / KEAP1-NFE2L2 pathway / CDK-mediated phosphorylation and removal of Cdc6 / Neddylation / FBXL7 down-regulates AURKA during mitotic entry and in early mitosis / Orc1 removal from chromatin / MAPK6/MAPK4 signaling / Antigen processing: Ubiquitination & Proteasome degradation / Ub-specific processing proteases / positive regulation of RNA polymerase II transcription preinitiation complex assembly / proteasome complex / ubiquitin-dependent protein catabolic process / proteasome-mediated ubiquitin-dependent protein catabolic process / ATP hydrolysis activity / ATP binding / identical protein binding / nucleus / cytoplasm / cytosol類似検索 - 分子機能 Helicase, Ruva Protein; domain 3 - #60 / Proteasomal ATPase OB C-terminal domain / Proteasomal ATPase OB C-terminal domain / Ankyrin repeat-containing domain / ATPase, AAA-type, conserved site / AAA-protein family signature. / Helicase, Ruva Protein; domain 3 / Ankyrin repeat / Ankyrin repeats (3 copies) / ATPase family associated with various cellular activities (AAA) ...Helicase, Ruva Protein; domain 3 - #60 / Proteasomal ATPase OB C-terminal domain / Proteasomal ATPase OB C-terminal domain / Ankyrin repeat-containing domain / ATPase, AAA-type, conserved site / AAA-protein family signature. / Helicase, Ruva Protein; domain 3 / Ankyrin repeat / Ankyrin repeats (3 copies) / ATPase family associated with various cellular activities (AAA) / Ankyrin repeat profile. / Ankyrin repeat region circular profile. / ankyrin repeats / ATPase, AAA-type, core / Ankyrin repeat / Ankyrin repeat-containing domain superfamily / Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat / Alpha Horseshoe / ATPases associated with a variety of cellular activities / AAA+ ATPase domain / Nucleic acid-binding, OB-fold / P-loop containing nucleoside triphosphate hydrolase / Orthogonal Bundle / Mainly Alpha類似検索 - ドメイン・相同性 26S proteasome regulatory subunit 6B homolog / Probable 26S proteasome regulatory subunit p28類似検索 - 構成要素 |
---|
生物種 | ![](img/tx_yeast.gif) Saccharomyces cerevisiae (パン酵母) |
---|
手法 | X線回折 / シンクロトロン / 分子置換 / 解像度: 2.2 Å |
---|
データ登録者 | Yokoyama, S. / Padmanabhan, B. / RIKEN Structural Genomics/Proteomics Initiative (RSGI) |
---|
引用 | ジャーナル: Biochem.Biophys.Res.Commun. / 年: 2007 タイトル: Structural basis for the recognition between the regulatory particles Nas6 and Rpt3 of the yeast 26S proteasome 著者: Nakamura, Y. / Umehara, T. / Tanaka, A. / Horikoshi, M. / Padmanabhan, B. / Yokoyama, S. |
---|
履歴 | 登録 | 2006年9月29日 | 登録サイト: PDBJ / 処理サイト: PDBJ |
---|
改定 1.0 | 2007年7月17日 | Provider: repository / タイプ: Initial release |
---|
改定 1.1 | 2008年4月30日 | Group: Version format compliance |
---|
改定 1.2 | 2011年7月13日 | Group: Version format compliance |
---|
改定 1.3 | 2024年3月13日 | Group: Data collection / Database references カテゴリ: chem_comp_atom / chem_comp_bond ...chem_comp_atom / chem_comp_bond / database_2 / struct_ref_seq_dif Item: _database_2.pdbx_DOI / _database_2.pdbx_database_accession / _struct_ref_seq_dif.details |
---|
改定 1.4 | 2024年4月3日 | Group: Refinement description / カテゴリ: pdbx_initial_refinement_model |
---|
|
---|